The role of basement membranes in cardiac biology and disease

por Boland, Erin, Quondamatteo, Fabio, Van Agtmael, Tom
Publicado 2021

Four decades in the making: Collagen III and mechanisms of vascular Ehlers Danlos Syndrome

por Omar, Ramla, Malfait, Fransiska, Van Agtmael, Tom
Publicado 2021

Editorial: Molecular Mechanisms of Heritable Connective Tissue Disorders

por Malfait, Fransiska, Forlino, Antonella, Sengle, Gerhard, Van Agtmael, Tom
Publicado 2022

Basement membrane collagens and disease mechanisms

por Gatseva, Anna, Sin, Yuan Yan, Brezzo, Gaia, Van Agtmael, Tom
Publicado 2019

Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke

por Murray, Lydia S., Lu, Yinhui, Taggart, Aislynn, Van Regemorter, Nicole, Vilain, Catheline, Abramowicz, Marc, Kadler, Karl E., Van Agtmael, Tom
Publicado 2014

The Chemical Chaperone, PBA, Reduces ER Stress and Autophagy and Increases Collagen IV α5 Expression in Cultured Fibroblasts From Men With X-Linked Alport Syndrome and Missense Mut...

por Wang, Dongmao, Mohammad, Mardhiah, Wang, Yanyan, Tan, Rachel, Murray, Lydia S., Ricardo, Sharon, Dagher, Hayat, van Agtmael, Tom, Savige, Judy
Publicado 2017

Tendon Is Covered by a Basement Membrane Epithelium That Is Required for Cell Retention and the Prevention of Adhesion Formation

por Taylor, Susan H., Al-Youha, Sarah, Van Agtmael, Tom, Lu, Yinhui, Wong, Jason, McGrouther, Duncan A., Kadler, Karl E.
Publicado 2011

4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease

por Jones, Frances E, Murray, Lydia S, McNeilly, Sarah, Dean, Afshan, Aman, Alisha, Lu, Yinhui, Nikolova, Nija, Malomgré, Ruben, Horsburgh, Karen, Holmes, William M, Kadler, Karl E, Van Agtmael, Tom
Publicado 2019

ER stress and basement membrane defects combine to cause glomerular and tubular renal disease resulting from Col4a1 mutations in mice

por Jones, Frances E., Bailey, Matthew A., Murray, Lydia S., Lu, Yinhui, McNeilly, Sarah, Schlötzer-Schrehardt, Ursula, Lennon, Rachel, Sado, Yoshikazu, Brownstein, David G., Mullins, John J., Kadler, Karl E., Van Agtmael, Tom
Publicado 2016

Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease

por Pokhilko, Alexandra, Brezzo, Gaia, Handunnetthi, Lahiru, Heilig, Raphael, Lennon, Rachel, Smith, Colin, Allan, Stuart M, Granata, Alessandra, Sinha, Sanjay, Wang, Tao, Markus, Hugh S, Naba, Alexandra, Fischer, Roman, Van Agtmael, Tom, Horsburgh, Karen, Cader, M Zameel
Publicado 2021

Vascular Collagen Type-IV in Hypertension and Cerebral Small Vessel Disease

por Kumar, Apoorva A., Yeo, Natalie, Whittaker, Max, Attra, Priya, Barrick, Thomas R., Bridges, Leslie R., Dickson, Dennis W., Esiri, Margaret M., Farris, Chad W., Graham, Delyth, Lin, Wen Lang, Meijles, Daniel N., Pereira, Anthony C., Perry, Gregory, Rosene, Douglas L., Shtaya, Anan B., Van Agtmael, Tom, Zamboni, Giovanna, Hainsworth, Atticus H.
Publicado 2022

Rare Missense Functional Variants at COL4A1 and COL4A2 in Sporadic Intracerebral Hemorrhage

por Chung, Jaeyoon, Hamilton, Graham, Kim, Minsup, Marini, Sandro, Montgomery, Bailey, Henry, Jonathan, Cho, Art E., Brown, Devin L., Worrall, Bradford B., Meschia, James F., Silliman, Scott L., Selim, Magdy, Tirschwell, David L., Kidwell, Chelsea S., Kissela, Brett, Greenberg, Steven M., Viswanathan, Anand, Goldstein, Joshua N., Langefeld, Carl D., Rannikmae, Kristiina, Sudlow, Catherine L.M., Samarasekera, Neshika, Rodrigues, Mark, Al-Shahi Salman, Rustam, Prendergast, James G.D., Harris, Sarah E., Deary, Ian, Woo, Daniel, Rosand, Jonathan, Van Agtmael, Tom, Anderson, Christopher D.
Publicado 2021