Development of a Human iPSC Cardiomyocyte-Based Scoring System for Cardiac Hazard Identification in Early Drug Safety De-risking

por Kopljar, Ivan, Lu, Hua Rong, Van Ammel, Karel, Otava, Martin, Tekle, Fetene, Teisman, Ard, Gallacher, David J.
Publicado 2018

High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca(2+) Fluorescence Measurements in Hum...

por Lu, Hua-Rong, Seo, Manabu, Kreir, Mohamed, Tanaka, Tetsuya, Yamoto, Rie, Altrocchi, Cristina, van Ammel, Karel, Tekle, Fetene, Pham, Ly, Yao, Xiang, Teisman, Ard, Gallacher, David J.
Publicado 2023

Application of a systems pharmacology model for translational prediction of hERG‐mediated QTc prolongation

por Gotta, Verena, Yu, Zhiyi, Cools, Frank, van Ammel, Karel, Gallacher, David J., Visser, Sandra A. G., Sannajust, Frederick, Morissette, Pierre, Danhof, Meindert, van der Graaf, Piet H.
Publicado 2016