Inhibition of NF-κB in Tumor Cells Exacerbates Immune Cell Activation Following Photodynamic Therapy

por Broekgaarden, Mans, Kos, Milan, Jurg, Freek A., van Beek, Adriaan A., van Gulik, Thomas M., Heger, Michal
Publicado 2015

Aged mice display altered numbers and phenotype of basophils, and bone marrow-derived basophil activation, with a limited role for aging-associated microbiota

por van Beek, Adriaan A., Fransen, Floris, Meijer, Ben, de Vos, Paul, Knol, Edward F., Savelkoul, Huub F. J.
Publicado 2018

Age-associated Impairment of the Mucus Barrier Function is Associated with Profound Changes in Microbiota and Immunity

por Sovran, Bruno, Hugenholtz, Floor, Elderman, Marlies, Van Beek, Adriaan A., Graversen, Katrine, Huijskes, Myrte, Boekschoten, Mark V., Savelkoul, Huub F. J., De Vos, Paul, Dekker, Jan, Wells, Jerry M.
Publicado 2019

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1(−/Δ7) mice

por van der Lugt, Benthe, van Beek, Adriaan A., Aalvink, Steven, Meijer, Ben, Sovran, Bruno, Vermeij, Wilbert P., Brandt, Renata M. C., de Vos, Willem M., Savelkoul, Huub F. J., Steegenga, Wilma T., Belzer, Clara
Publicado 2019

Aged Gut Microbiota Contributes to Systemical Inflammaging after Transfer to Germ-Free Mice

por Fransen, Floris, van Beek, Adriaan A., Borghuis, Theo, Aidy, Sahar El, Hugenholtz, Floor, van der Gaast – de Jongh, Christa, Savelkoul, Huub F. J., De Jonge, Marien I., Boekschoten, Mark V., Smidt, Hauke, Faas, Marijke M., de Vos, Paul
Publicado 2017

The Impact of Gut Microbiota on Gender-Specific Differences in Immunity

por Fransen, Floris, van Beek, Adriaan A., Borghuis, Theo, Meijer, Ben, Hugenholtz, Floor, van der Gaast-de Jongh, Christa, Savelkoul, Huub F., de Jonge, Marien I., Faas, Marijke M., Boekschoten, Mark V., Smidt, Hauke, El Aidy, Sahar, de Vos, Paul
Publicado 2017

Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer

por Zhou, Guoying, Noordam, Lisanne, Sprengers, Dave, Doukas, Michail, Boor, Patrick P. C., van Beek, Adriaan A., Erkens, Remco, Mancham, Shanta, Grünhagen, Dirk, Menon, Anand G., Lange, Johan F., Burger, Pim J. W. A., Brandt, Alexandra, Galjart, Boris, Verhoef, Cornelis, Kwekkeboom, Jaap, Bruno, Marco J.
Publicado 2018

GITR ligation enhances functionality of tumor‐infiltrating T cells in hepatocellular carcinoma

por van Beek, Adriaan A., Zhou, Guoying, Doukas, Michail, Boor, Patrick P.C., Noordam, Lisanne, Mancham, Shanta, Campos Carrascosa, Lucia, van der Heide‐Mulder, Marieke, Polak, Wojciech G., Ijzermans, Jan N.M., Pan, Qiuwei, Heirman, Carlo, Mahne, Ashley, Bucktrout, Samantha L., Bruno, Marco J., Sprengers, Dave, Kwekkeboom, Jaap
Publicado 2019

GITR Ligation Improves Anti-PD1-Mediated Restoration of Human MMR-Proficient Colorectal Carcinoma Tumor-Derived T Cells

por Rakké, Yannick S., Campos Carrascosa, Lucia, van Beek, Adriaan A., de Ruiter, Valeska, van Gemerden, Rachelle S., Doukas, Michail, Doornebosch, Pascal G., Vermaas, Maarten, ter Borg, Susan, van der Harst, Erwin, Coene, Peter Paul L.O., Kliffen, Mike, Grünhagen, Dirk J., Verhoef, Cornelis, IJzermans, Jan N.M., Kwekkeboom, Jaap, Sprengers, Dave
Publicado 2022

Supplementation with Lactobacillus plantarum WCFS1 Prevents Decline of Mucus Barrier in Colon of Accelerated Aging Ercc1(−/Δ7) Mice

por van Beek, Adriaan A., Sovran, Bruno, Hugenholtz, Floor, Meijer, Ben, Hoogerland, Joanne A., Mihailova, Violeta, van der Ploeg, Corine, Belzer, Clara, Boekschoten, Mark V., Hoeijmakers, Jan H. J., Vermeij, Wilbert P., de Vos, Paul, Wells, Jerry M., Leenen, Pieter J. M., Nicoletti, Claudio, Hendriks, Rudi W., Savelkoul, Huub F. J.
Publicado 2016

FcγRIIB engagement drives agonistic activity of Fc-engineered αOX40 antibody to stimulate human tumor-infiltrating T cells

por Campos Carrascosa, Lucia, van Beek, Adriaan A, de Ruiter, Valeska, Doukas, Michail, Wei, Jie, Fisher, Timothy S, Ching, Keith, Yang, Wenjing, van Loon, Karlijn, Boor, Patrick P C, Rakké, Yannick S, Noordam, Lisanne, Doornebosch, Pascal, Grünhagen, Dirk, Verhoef, Kees, Polak, Wojciech G, IJzermans, Jan N M, Ni, Irene, Yeung, Yik Andy, Salek-Ardakani, Shahram, Sprengers, Dave, Kwekkeboom, Jaap
Publicado 2020