A Mode-of-Action Approach for the Identification of Genotoxic Carcinogens

por Hernández, Lya G., van Benthem, Jan, Johnson, George E.
Publicado 2013

Hazardous Compounds in Tobacco Smoke

por Talhout, Reinskje, Schulz, Thomas, Florek, Ewa, van Benthem, Jan, Wester, Piet, Opperhuizen, Antoon
Publicado 2011

In utero Exposure to Genotoxicants Leading to Genetic Mosaicism: An Overlooked Window of Susceptibility in Genetic Toxicology Testing?

por Godschalk, Roger W. L., Yauk, Carole L., van Benthem, Jan, Douglas, George R., Marchetti, Francesco
Publicado 2019

ECVAM retrospective validation of in vitro micronucleus test (MNT)

por Corvi, Raffaella, Albertini, Silvio, Hartung, Thomas, Hoffmann, Sebastian, Maurici, Daniela, Pfuhler, Stefan, van Benthem, Jan, Vanparys, Philippe
Publicado 2008

Comparison of clastogen-induced gene expression profiles in wild-type and DNA repair-deficient Rad54/Rad54B cells

por Mahabir, Anuska G, Schaap, Mirjam M, Pennings, Jeroen LA, van Benthem, Jan, Hendriksen, Coenraad FM, van Steeg, Harry
Publicado 2010

Establishing a quantitative framework for regulatory interpretation of genetic toxicity dose–response data: Margin of exposure case study of 48 compounds with both in vivo mutageni...

por Chepelev, Nikolai, Long, Alexandra S., Beal, Marc, Barton‐Maclaren, Tara, Johnson, George, Dearfield, Kerry L., Roberts, Daniel J., van Benthem, Jan, White, Paul
Publicado 2023

Benzo(a)pyrene induces similar gene expression changes in testis of DNA repair proficient and deficient mice

por Verhofstad, Nicole, Pennings, Jeroen LA, van Oostrom, Conny ThM, van Benthem, Jan, van Schooten, Frederik J, van Steeg, Harry, Godschalk, Roger WL
Publicado 2010

Impact of sampling time on the detection of mutations in rapidly proliferating tissues using transgenic rodent gene mutation models: A review

por Douglas, George R., Beevers, Carol, Gollapudi, Bhaskar, Keig‐Shevlin, Zena, Kirkland, David, O'Brien, Jason M., van Benthem, Jan, Yauk, Carole L., Young, Robert R., Marchetti, Francesco
Publicado 2022

Utility of a next generation framework for assessment of genomic damage: A case study using the industrial chemical benzene

por Luijten, Mirjam, Ball, Nicholas S., Dearfield, Kerry L., Gollapudi, B. Bhaskar, Johnson, George E., Madia, Federica, Peel, Lauren, Pfuhler, Stefan, Settivari, Raja S., ter Burg, Wouter, White, Paul A., van Benthem, Jan
Publicado 2019

Clarification of some aspects related to genotoxicity assessment

por Hardy, Anthony, Benford, Diane, Halldorsson, Thorhallur, Jeger, Michael, Knutsen, Helle Katrine, More, Simon, Naegeli, Hanspeter, Noteborn, Hubert, Ockleford, Colin, Ricci, Antonia, Rychen, Guido, Silano, Vittorio, Solecki, Roland, Turck, Dominique, Younes, Maged, Aquilina, Gabriele, Crebelli, Riccardo, Gürtler, Rainer, Hirsch‐Ernst, Karen Ildico, Mosesso, Pasquale, Nielsen, Elsa, van Benthem, Jan, Carfì, Maria, Georgiadis, Nikolaos, Maurici, Daniela, Parra Morte, Juan, Schlatter, Josef
Publicado 2017

Scientific Opinion on Flavouring Group Evaluation 74, Revision 4 (FGE.74Rev4): Consideration of aliphatic sulphides and thiols evaluated by JECFA (53rd and 61st meeting) structural...

por Silano, Vittorio, Bolognesi, Claudia, Castle, Laurence, Chipman, Kevin, Cravedi, Jean‐Pierre, Engel, Karl‐Heinz, Fowler, Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kärenlampi, Sirpa, Milana, Maria Rosaria, Pfaff, Karla, Riviere, Gilles, Srinivasan, Jannavi, Tavares Poças, Maria de Fátima, Tlustos, Christina, Wölfle, Detlef, Zorn, Holger, Benigni, Romualdo, Brimer, Leon, Mulder, Gerard, Oskarsson, Agneta, Svendsen, Camilla, van Benthem, Jan, Anastassiadou, Maria, Saarma, Siiri, Mennes, Wim
Publicado 2018

Scientific Opinion of Flavouring Group Evaluation 411 (FGE.411): 2‐(4‐methylphenoxy)‐N‐(1H‐pyrazol‐3‐yl)‐N‐(thiophen‐2‐ylmethyl)acetamide from chemical group 30 (miscellaneous subs...

por Younes, Maged, Aquilina, Gabriele, Castle, Laurence, Engel, Karl‐Heinz, Fowler, Paul, Frutos Fernandez, Maria Jose, Fürst, Peter, Gundert‐Remy, Ursula, Gürtler, Rainer, Husøy, Trine, Moldeus, Peter, Oskarsson, Agneta, Rainieri, Sandra, Shah, Romina, Waalkens‐Berendsen, Ine, Wölfle, Detlef, Benigni, Romualdo, Binderup, Mona‐Lise, Bolognesi, Claudia, Brimer, Leon, Chipman, Kevin, Marcon, Francesca, Marzin, Daniel, Mosesso, Pasquale, Mulder, Gerard, Svendsen, Camilla, van Benthem, Jan, Anastassiadou, Maria, Carfí, Maria, Mennes, Wim
Publicado 2018

Scientific opinion on flavouring group evaluation 77, revision 3 (FGE.77Rev3): consideration of pyridine, pyrrole and quinoline derivatives evaluated by JECFA (63rd meeting) struct...

por Silano, Vittorio, Bolognesi, Claudia, Castle, Laurence, Chipman, Kevin, Cravedi, Jean‐Pierre, Engel, Karl‐Heinz, Fowler, Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kärenlampi, Sirpa, Milana, Maria Rosaria, Pfaff, Karla, Riviere, Gilles, Srinivasan, Jannavi, Tavares Poças, Maria de Fátima, Tlustos, Christina, Wölfle, Detlef, Zorn, Holger, Benigni, Romualdo, Binderup, Mona‐Lise, Brimer, Leon, Marcon, Francesca, Marzin, Daniel, Mosesso, Pasquale, Mulder, Gerard, Oskarsson, Agneta, Svendsen, Camilla, van Benthem, Jan, Anastassiadou, Maria, Carfì, Maria, Mennes, Wim
Publicado 2018

Scientific Opinion of Flavouring Group Evaluation 406 (FGE.406): (S)‐1‐(3‐(((4‐amino‐2,2‐dioxido‐1H‐benzo[c][1,2,6]thiadiazin‐5‐yl)oxy)methyl)piperidin‐1‐yl)‐3‐methylbutan‐1‐one...

por Silano, Vittorio, Bolognesi, Claudia, Castle, Laurence, Chipman, Kevin, Cravedi, Jean‐Pierre, Engel, Karl‐Heinz, Fowler, Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kärenlampi, Sirpa, Milana, Maria Rosaria, Pfaff, Karla, Riviere, Gilles, Srinivasan, Jannavi, Tavares Poças, Maria de Fátima, Tlustos, Christina, Wölfle, Detlef, Zorn, Holger, Beckman Sundh, Ulla, Benigni, Romualdo, Binderup, Mona‐Lise, Brimer, Leon, Marcon, Francesca, Marzin, Daniel, Mosesso, Pasquale, Mulder, Gerard, Oskarsson, Agneta, Svendsen, Camilla, Van Benthem, Jan, Anastassiadou, Maria, Carfì, Maria, Mennes, Wim
Publicado 2018