Enhanced recruitment of genetically modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient

por Siddiqui, Imran, Erreni, Marco, van Brakel, Mandy, Debets, Reno, Allavena, Paola
Publicado 2016

Lack of B and T cell reactivity towards IDH1(R132H) in blood and tumor tissue from LGG patients

por Weenink, Bas, van Brakel, Mandy, Wijers, Rebecca, Sillevis Smitt, Peter A. E., French, Pim J., Debets, Reno
Publicado 2019

T Cells Expressing a TCR-Like Antibody Selected Against the Heteroclitic Variant of a Shared MAGE-A Epitope Do Not Recognise the Cognate Epitope

por Saeed, Mesha, Schooten, Erik, van Brakel, Mandy, K. Cole, David, ten Hagen, Timo L. M., Debets, Reno
Publicado 2020

Targeting melanoma with immunoliposomes coupled to anti-MAGE A1 TCR-like single-chain antibody

por Saeed, Mesha, van Brakel, Mandy, Zalba, Sara, Schooten, Erik, Rens, Joost AP, Koning, Gerben A, Debets, Reno, ten Hagen, Timo LM
Publicado 2016

TCR Gene Transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 Epitopes as Melanoma-Specific Immune Targets

por Straetemans, Trudy, van Brakel, Mandy, van Steenbergen, Sabine, Broertjes, Marieke, Drexhage, Joost, Hegmans, Joost, Lambrecht, Bart N., Lamers, Cor, Bruggen, Pierre van Der, Coulie, Pierre G., Debets, Reno
Publicado 2012

Germline Variation in PDCD1 Is Associated with Overall Survival in Patients with Metastatic Melanoma Treated with Anti-PD-1 Monotherapy

por de With, Mirjam, Hurkmans, Daan P., Oomen-de Hoop, Esther, Lalouti, Ayoub, Bins, Sander, El Bouazzaoui, Samira, van Brakel, Mandy, Debets, Reno, Aerts, Joachim G. J. V., van Schaik, Ron H. N., Mathijssen, Ron H. J., van der Veldt, Astrid A. M.
Publicado 2021

A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial cancer

por Rijnders, Maud, Robbrecht, Debbie G. J., Oostvogels, Astrid A. M., van Brakel, Mandy, Boormans, Joost L., Aarts, Maureen J. B., Balcioglu, Hayri E., Hamberg, Paul, Voortman, Jens, Westgeest, Hans M., Lolkema, Martijn P., de Wit, Ronald, van der Veldt, Astrid A. M., Debets, Reno
Publicado 2022

CD45RA(+)CCR7(−) CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab

por Kunert, Andre, Basak, Edwin A., Hurkmans, Daan P., Balcioglu, Hayri E., Klaver, Yarne, van Brakel, Mandy, Oostvogels, Astrid A. M., Lamers, Cor H. J., Bins, Sander, Koolen, Stijn L. W., van der Veldt, Astrid A. M., Sleijfer, Stefan, Mathijssen, Ron H. J., Aerts, Joachim G. J. V., Debets, Reno
Publicado 2019

Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer

por Hurkmans, Daan P, Verdegaal, Els M E, Hogan, Sabrina A, de Wijn, Rik, Hovestad, Lies, van den Heuvel, Dianne M A, Ruijtenbeek, Rob, Welters, Marij J P, van Brakel, Mandy, Basak, Edwin A, Pinedo, Herbert M, Lamers, Cor H J, van de Werken, Harmen J G, Groten, John P, Debets, Reno, Levesque, Mitchell P, Dummer, Reinhard, Kapiteijn, Ellen, Mathijssen, Ron H J, Aerts, Joachim G J V, van der Burg, Sjoerd H
Publicado 2020