Efficient diastereoselective synthesis of a new class of azanucleosides: 2′-homoazanucleosides

por Bouton, Jakob, Van Hecke, Kristof, Van Calenbergh, Serge
Publicado 2017

Synthesis of pyrrolidine-based hamamelitannin analogues as quorum sensing inhibitors in Staphylococcus aureus

por Bouton, Jakob, Van Hecke, Kristof, Rasooly, Reuven, Van Calenbergh, Serge
Publicado 2018

Exploring the purine core of 3′-C-ethynyladenosine (EAdo) in search of novel nucleoside therapeutics

por Hulpia, Fabian, Balzarini, Jan, Schols, Dominique, Andrei, Graciela, Snoeck, Robert, Van Calenbergh, Serge
Publicado 2016

Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR

por Brackman, Gilles, Defoirdt, Tom, Miyamoto, Carol, Bossier, Peter, Van Calenbergh, Serge, Nelis, Hans, Coenye, Tom
Publicado 2008

Crystal Structures of Bovine CD1d Reveal Altered αGalCer Presentation and a Restricted A’ Pocket Unable to Bind Long-Chain Glycolipids

por Wang, Jing, Guillaume, Joren, Pauwels, Nora, Van Calenbergh, Serge, Van Rhijn, Ildiko, Zajonc, Dirk M.
Publicado 2012

Synthesis and structure-activity relationships of cerebroside analogues as substrates of cerebroside sulphotransferase and discovery of a competitive inhibitor

por Li, Wenjin, Guillaume, Joren, Baqi, Younis, Wachsmann, Isabell, Gieselmann, Volkmar, Van Calenbergh, Serge, Müller, Christa E.
Publicado 2020

6-Methyl-7-deazapurine nucleoside analogues as broad-spectrum antikinetoplastid agents

por Lin, Cai, Hulpia, Fabian, Karalic, Izet, De Schepper, Laurens, Maes, Louis, Caljon, Guy, Van Calenbergh, Serge
Publicado 2021

Synthesis of a 3′-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides

por Hulpia, Fabian, Noppen, Sam, Schols, Dominique, Andrei, Graciela, Snoeck, Robert, Liekens, Sandra, Vervaeke, Peter, Van Calenbergh, Serge
Publicado 2018

Structure-Activity Relationship of Cinnamaldehyde Analogs as Inhibitors of AI-2 Based Quorum Sensing and Their Effect on Virulence of Vibrio spp

por Brackman, Gilles, Celen, Shari, Hillaert, Ulrik, Van Calenbergh, Serge, Cos, Paul, Maes, Louis, Nelis, Hans J., Coenye, Tom
Publicado 2011

Design, Synthesis and Characterization of a New Series of Fluorescent Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulators

por Fernández-Dueñas, Víctor, Qian, Mingcheng, Argerich, Josep, Amaral, Carolina, Risseeuw, Martijn D.P., Van Calenbergh, Serge, Ciruela, Francisco
Publicado 2020

The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release

por Brackman, Gilles, Breyne, Koen, De Rycke, Riet, Vermote, Arno, Van Nieuwerburgh, Filip, Meyer, Evelyne, Van Calenbergh, Serge, Coenye, Tom
Publicado 2016

Synthesis of Extended Uridine Phosphonates Derived from an Allosteric P2Y(2) Receptor Ligand

por Song, Lijun, Risseeuw, Martijn D. P., Karalic, Izet, Barrett, Matthew O., Brown, Kyle A., Harden, T. Kendall, Van Calenbergh, Serge
Publicado 2014

Synthetic Fosmidomycin Analogues with Altered Chelating Moieties Do Not Inhibit 1-Deoxy-d-xylulose 5-phosphate Reductoisomerase or Plasmodium falciparum Growth In Vitro

por Chofor, René, Risseeuw, Martijn D.P., Pouyez, Jenny, Johny, Chinchu, Wouters, Johan, Dowd, Cynthia S., Couch, Robin D., Van Calenbergh, Serge
Publicado 2014

1-(Piperidin-3-yl)thymine amides as inhibitors of M. tuberculosis thymidylate kinase

por Jian, Yanlin, Risseeuw, Martijn D. P., Froeyen, Mathy, Song, Lijun, Cappoen, Davie, Cos, Paul, Munier-Lehmann, Hélène, van Calenbergh, Serge
Publicado 2019

Efficient Divergent Synthesis of New Immunostimulant 4″-Modified α-Galactosylceramide Analogues

por Janssens, Jonas, Decruy, Tine, Venken, Koen, Seki, Toshiyuki, Krols, Simon, Van der Eycken, Johan, Tsuji, Moriya, Elewaut, Dirk, Van Calenbergh, Serge
Publicado 2017

1-(1-Arylethylpiperidin-4-yl)thymine Analogs as Antimycobacterial TMPK Inhibitors

por Jian, Yanlin, Hulpia, Fabian, D. P. Risseeuw, Martijn, Forbes, He Eun, Caljon, Guy, Munier-Lehmann, Hélène, I. M. Boshoff, Helena, Van Calenbergh, Serge
Publicado 2020

An In Silico Approach for Modelling T-Helper Polarizing iNKT Cell Agonists

por De Spiegeleer, Anton, Wynendaele, Evelien, Vandekerckhove, Matthias, Stalmans, Sofie, Boucart, Maxime, Van Den Noortgate, Nele, Venken, Koen, Van Calenbergh, Serge, Aspeslagh, Sandrine, Elewaut, Dirk
Publicado 2014

Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics

por Crabbé, Aurélie, Ostyn, Lisa, Staelens, Sorien, Rigauts, Charlotte, Risseeuw, Martijn, Dhaenens, Maarten, Daled, Simon, Van Acker, Heleen, Deforce, Dieter, Van Calenbergh, Serge, Coenye, Tom
Publicado 2019

Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness

por Hulpia, Fabian, Mabille, Dorien, Campagnaro, Gustavo D., Schumann, Gabriela, Maes, Louis, Roditi, Isabel, Hofer, Anders, de Koning, Harry P., Caljon, Guy, Van Calenbergh, Serge
Publicado 2019

4E Interacting Protein as a Potential Novel Drug Target for Nucleoside Analogues in Trypanosoma brucei

por Mabille, Dorien, Cardoso Santos, Camila, Hendrickx, Rik, Claes, Mathieu, Takac, Peter, Clayton, Christine, Hendrickx, Sarah, Hulpia, Fabian, Maes, Louis, Van Calenbergh, Serge, Caljon, Guy
Publicado 2021