The Unique Phenotype of Lipid-Laden Macrophages

por van Eijk, Marco, Aerts, Johannes M. F. G.
Publicado 2021

Lyso-glycosphingolipids: presence and consequences

por van Eijk, Marco, Ferraz, Maria J., Boot, Rolf G., Aerts, Johannes M.F.G.
Publicado 2020

Glycoprotein Non-Metastatic Protein B: An Emerging Biomarker for Lysosomal Dysfunction in Macrophages

por van der Lienden, Martijn J.C., Gaspar, Paulo, Boot, Rolf, Aerts, Johannes M.F.G., van Eijk, Marco
Publicado 2018

Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival

por Gabriel, Tanit L., Mirzaian, Mina, Hooibrink, Berend, Ottenhoff, Roelof, van Roomen, Cindy, Aerts, Johannes M. F. G., van Eijk, Marco
Publicado 2017

HEPES‐buffering of bicarbonate‐containing culture medium perturbs lysosomal glucocerebrosidase activity

por van der Lienden, Martijn J. C., Aten, Jan, Boot, Rolf G., van Eijk, Marco, Aerts, Johannes M. F. G., Kuo, Chi‐Lin
Publicado 2022

Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis

por Gaspar, Paulo, Kallemeijn, Wouter W., Strijland, Anneke, Scheij, Saskia, Van Eijk, Marco, Aten, Jan, Overkleeft, Herman S., Balreira, Andrea, Zunke, Friederike, Schwake, Michael, Sá Miranda, Clara, Aerts, Johannes M. F. G.
Publicado 2014

Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease

por Marques, André R. A., Gabriel, Tanit L., Aten, Jan, van Roomen, Cindy P. A. A., Ottenhoff, Roelof, Claessen, Nike, Alfonso, Pilar, Irún, Pilar, Giraldo, Pilar, Aerts, Johannes M. F. G., van Eijk, Marco
Publicado 2016

Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism

por Lombardo, Elisa, van Roomen, Cindy P. A. A., van Puijvelde, Gijs H., Ottenhoff, Roelof, van Eijk, Marco, Aten, Jan, Kuiper, Johan, Overkleeft, Herman S., Groen, Albert K., Verhoeven, Arthur J., Aerts, Johannes M. F. G., Bietrix, Florence
Publicado 2012

GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice

por van der Lienden, Martijn J. C., Aten, Jan, Marques, André R. A., Waas, Ingeborg S. E., Larsen, Per W. B., Claessen, Nike, van der Wel, Nicole N., Ottenhoff, Roelof, van Eijk, Marco, Aerts, Johannes M. F. G.
Publicado 2021

Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation

por van Eijk, Marco, Aten, Jan, Bijl, Nora, Ottenhoff, Roelof, van Roomen, Cindy P. A. A., Dubbelhuis, Peter F., Seeman, Ingar, Ghauharali-van der Vlugt, Karen, Overkleeft, Hermen S., Arbeeny, Cynthia, Groen, Albert K., Aerts, Johannes M. F. G.
Publicado 2009

HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution

por Tol, Marc J., van der Lienden, Martijn J.C., Gabriel, Tanit L., Hagen, Jacob J., Scheij, Saskia, Veenendaal, Tineke, Klumperman, Judith, Donker-Koopman, Wilma E., Verhoeven, Arthur J., Overkleeft, Hermen, Aerts, Johannes M., Argmann, Carmen A., van Eijk, Marco
Publicado 2018

A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity

por Tol, Marc J., Ottenhoff, Roelof, van Eijk, Marco, Zelcer, Noam, Aten, Jan, Houten, Sander M., Geerts, Dirk, van Roomen, Cindy, Bierlaagh, Marlou C., Scheij, Saskia, Hoeksema, Marten A., Aerts, Johannes M., Bogan, Jonathan S., Dorn, Gerald W., Argmann, Carmen A., Verhoeven, Arthur J.
Publicado 2016

Elevation of glycoprotein nonmetastatic melanoma protein B in type 1 Gaucher disease patients and mouse models

por Kramer, Gertjan, Wegdam, Wouter, Donker‐Koopman, Wilma, Ottenhoff, Roelof, Gaspar, Paulo, Verhoek, Marri, Nelson, Jessica, Gabriel, Tanit, Kallemeijn, Wouter, Boot, Rolf G., Laman, Jon D., Vissers, Johannes P.C., Cox, Timothy, Pavlova, Elena, Moran, Mary Teresa, Aerts, Johannes M., van Eijk, Marco
Publicado 2016

Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes

por Herrera Moro Chao, Daniela, Kallemeijn, Wouter W., Marques, Andre R. A., Orre, Marie, Ottenhoff, Roelof, van Roomen, Cindy, Foppen, Ewout, Renner, Maria C., Moeton, Martina, van Eijk, Marco, Boot, Rolf G., Kamphuis, Willem, Hol, Elly M., Aten, Jan, Overkleeft, Hermen S., Kalsbeek, Andries, Aerts, Johannes M. F. G.
Publicado 2015

Inflammation Aggravates Disease Severity in Marfan Syndrome Patients

por Radonic, Teodora, de Witte, Piet, Groenink, Maarten, de Waard, Vivian, Lutter, Rene, van Eijk, Marco, Jansen, Marnix, Timmermans, Janneke, Kempers, Marlies, Scholte, Arthur J., Hilhorst-Hofstee, Yvonne, van den Berg, Maarten P., van Tintelen, J. Peter, Pals, Gerard, Baars, Marieke J. H., Mulder, Barbara J. M., Zwinderman, Aeilko H.
Publicado 2012

Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular β-glucosidases

por Marques, André R. A., Mirzaian, Mina, Akiyama, Hisako, Wisse, Patrick, Ferraz, Maria J., Gaspar, Paulo, Ghauharali-van der Vlugt, Karen, Meijer, Rianne, Giraldo, Pilar, Alfonso, Pilar, Irún, Pilar, Dahl, Maria, Karlsson, Stefan, Pavlova, Elena V., Cox, Timothy M., Scheij, Saskia, Verhoek, Marri, Ottenhoff, Roelof, van Roomen, Cindy P. A. A., Pannu, Navraj S., van Eijk, Marco, Dekker, Nick, Boot, Rolf G., Overkleeft, Herman S., Blommaart, Edward, Hirabayashi, Yoshio, Aerts, Johannes M.
Publicado 2016