Structural Characterization of Binding Mode of Smoking Cessation Drugs to Nicotinic Acetylcholine Receptors through Study of Ligand Complexes with Acetylcholine-binding Protein

por Rucktooa, Prakash, Haseler, Claire A., van Elk, René, Smit, August B., Gallagher, Timothy, Sixma, Titia K.
Publicado 2012

A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and d-Tubocurarine by Different Cys-Loop Receptors

por Brams, Marijke, Pandya, Anshul, Kuzmin, Dmitry, van Elk, René, Krijnen, Liz, Yakel, Jerrel L., Tsetlin, Victor, Smit, August B., Ulens, Chris
Publicado 2011

Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms

por Otvos, Reka A., Krishnamoorthy Iyer, Janaki, van Elk, René, Ulens, Chris, Niessen, Wilfried M. A., Somsen, Govert W., Kini, R. Manjunatha, Smit, August B., Kool, Jeroen
Publicado 2015

Assembly of a π–π stack of ligands in the binding site of an acetylcholine-binding protein

por Stornaiuolo, Mariano, De Kloe, Gerdien E., Rucktooa, Prakash, Fish, Alexander, van Elk, René, Edink, Ewald S., Bertrand, Daniel, Smit, August B., de Esch, Iwan J. P., Sixma, Titia K.
Publicado 2013

AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity

por Dutertre, Sébastien, Ulens, Chris, Büttner, Regina, Fish, Alexander, van Elk, René, Kendel, Yvonne, Hopping, Gene, Alewood, Paul F, Schroeder, Christina, Nicke, Annette, Smit, August B, Sixma, Titia K, Lewis, Richard J
Publicado 2007

Structural basis of ligand recognition in 5-HT(3) receptors

por Kesters, Divya, Thompson, Andrew J, Brams, Marijke, van Elk, René, Spurny, Radovan, Geitmann, Matthis, Villalgordo, Jose M, Guskov, Albert, Helena Danielson, U, Lummis, Sarah C R, Smit, August B, Ulens, Chris
Publicado 2013

Miniaturized Bioaffinity Assessment Coupled to Mass Spectrometry for Guided Purification of Bioactives from Toad and Cone Snail

por Heus, Ferry, Otvos, Reka A., Aspers, Ruud L. E. G., van Elk, Rene, Halff, Jenny I., Ehlers, Andreas W., Dutertre, Sébastien, Lewis, Richard J., Wijmenga, Sybren, Smit, August B., Niessen, Wilfried M. A., Kool, Jeroen
Publicado 2014