Multimodal imaging of the dynamic brain tumor microenvironment during glioblastoma progression and in response to treatment

por Zomer, Anoek, Croci, Davide, Kowal, Joanna, van Gurp, Leon, Joyce, Johanna A.
Publicado 2022

An ENU-Mutagenesis Screen in the Mouse: Identification of Novel Developmental Gene Functions

por Wansleeben, Carolien, van Gurp, Léon, Feitsma, Harma, Kroon, Carla, Rieter, Ester, Verberne, Marlies, Guryev, Victor, Cuppen, Edwin, Meijlink, Frits
Publicado 2011

Generation of human islet cell type-specific identity genesets

por van Gurp, Léon, Fodoulian, Leon, Oropeza, Daniel, Furuyama, Kenichiro, Bru-Tari, Eva, Vu, Anh Nguyet, Kaddis, John S., Rodríguez, Iván, Thorel, Fabrizio, Herrera, Pedro L.
Publicado 2022

Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production

por Perez-Frances, Marta, van Gurp, Léon, Abate, Maria Valentina, Cigliola, Valentina, Furuyama, Kenichiro, Bru-Tari, Eva, Oropeza, Daniel, Carreaux, Taïna, Fujitani, Yoshio, Thorel, Fabrizio, Herrera, Pedro L.
Publicado 2021

Author Correction: Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production

por Perez-Frances, Marta, van Gurp, Léon, Abate, Maria Valentina, Cigliola, Valentina, Furuyama, Kenichiro, Bru-Tari, Eva, Oropeza, Daniel, Carreaux, Taïna, Fujitani, Yoshio, Thorel, Fabrizio, Herrera, Pedro L.
Publicado 2021

A Single-Cell Transcriptome Atlas of the Human Pancreas

por Muraro, Mauro J., Dharmadhikari, Gitanjali, Grün, Dominic, Groen, Nathalie, Dielen, Tim, Jansen, Erik, van Gurp, Leon, Engelse, Marten A., Carlotti, Francoise, de Koning, Eelco J.P., van Oudenaarden, Alexander
Publicado 2016

Sequential intravital imaging reveals in vivo dynamics of pancreatic tissue transplanted under the kidney capsule in mice

por van Gurp, Léon, Loomans, Cindy J. M., van Krieken, Pim P., Dharmadhikari, Gitanjali, Jansen, Erik, Ringnalda, Femke C. A. S., Beerling, Evelyne, van Rheenen, Jacco, de Koning, Eelco J. P.
Publicado 2016

β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis

por van Veelen, Wendy, Le, Ngoc H, Helvensteijn, Werner, Blonden, Lau, Theeuwes, Myrte, Bakker, Elvira R M, Franken, Patrick F, van Gurp, Léon, Meijlink, Frits, van der Valk, Martin A, Kuipers, Ernst J, Fodde, Riccardo, Smits, Ron
Publicado 2011

Diabetes Relief in Mice by Glucose-Sensing Insulin-Secreting Human α-Cells

por Furuyama, Kenichiro, Chera, Simona, van Gurp, Léon, Oropeza, Daniel, Ghila, Luiza, Damond, Nicolas, Vethe, Heidrun, Paulo, Joao A., Joosten, Antoinette M., Berney, Thierry, Bosco, Domenico, Dorrell, Craig, Grompe, Markus, Ræder, Helge, Roep, Bart O., Thorel, Fabrizio, Herrera, Pedro L.
Publicado 2019

Pancreatic Islet-Autonomous Insulin and Smoothened-Mediated Signaling Modulate Identity Changes of Glucagon(+) α-Cells

por Cigliola, Valentina, Ghila, Luiza, Thorel, Fabrizio, van Gurp, Léon, Baronnier, Delphine, Oropeza, Daniel, Gupta, Simone, Miyatsuka, Takeshi, Kaneto, Hideaki, Magnuson, Mark A., Osipovich, Anna B., Sander, Maike, Wright, Christopher V. E., Thomas, Melissa K., Furuyama, Kenichiro, Chera, Simona, Herrera, Pedro L.
Publicado 2018

Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential

por Loomans, Cindy J.M., Williams Giuliani, Nerys, Balak, Jeetindra, Ringnalda, Femke, van Gurp, Léon, Huch, Meritxell, Boj, Sylvia F., Sato, Toshiro, Kester, Lennart, de Sousa Lopes, Susana M. Chuva, Roost, Matthias S., Bonner-Weir, Susan, Engelse, Marten A., Rabelink, Ton J., Heimberg, Harry, Vries, Robert G.J., van Oudenaarden, Alexander, Carlotti, Françoise, Clevers, Hans, de Koning, Eelco J.P.
Publicado 2018