The multicellular interplay of microglia in health and disease: lessons from leukodystrophy

por Berdowski, Woutje M., Sanderson, Leslie E., van Ham, Tjakko J.
Publicado 2021

Neurodegenerative diseases: Lessons from genome-wide screens in small model organisms

por van Ham, Tjakko J, Breitling, Rainer, Swertz, Morris A, Nollen, Ellen A A
Publicado 2009

Macrophages Do Not Express the Phagocytic Receptor BAI1/ADGRB1

por Hsiao, Cheng-Chih, van der Poel, Marlijn, van Ham, Tjakko J., Hamann, Jörg
Publicado 2019

Large-scale Scanning Transmission Electron Microscopy (Nanotomy) of Healthy and Injured Zebrafish Brain

por Kuipers, Jeroen, Kalicharan, Ruby D., Wolters, Anouk H. G., van Ham, Tjakko J., Giepmans, Ben N.G.
Publicado 2016

Reverse genetic screen reveals that Il34 facilitates yolk sac macrophage distribution and seeding of the brain

por Kuil, Laura E., Oosterhof, Nynke, Geurts, Samuël N., van der Linde, Herma C., Meijering, Erik, van Ham, Tjakko J.
Publicado 2019

C. elegans Model Identifies Genetic Modifiers of α-Synuclein Inclusion Formation During Aging

por van Ham, Tjakko J., Thijssen, Karen L., Breitling, Rainer, Hofstra, Robert M. W., Plasterk, Ronald H. A., Nollen, Ellen A. A.
Publicado 2008

Gene expression profiling reveals a conserved microglia signature in larval zebrafish

por Mazzolini, Julie, Le Clerc, Sigrid, Morisse, Gregoire, Coulonges, Cédric, Kuil, Laura E., van Ham, Tjakko J., Zagury, Jean‐François, Sieger, Dirk
Publicado 2019

M-CSFR/CSF1R signaling regulates myeloid fates in zebrafish via distinct action of its receptors and ligands

por Hason, Martina, Mikulasova, Tereza, Machonova, Olga, Pombinho, Antonio, van Ham, Tjakko J., Irion, Uwe, Nüsslein-Volhard, Christiane, Bartunek, Petr, Svoboda, Ondrej
Publicado 2022

FLIPPER, a combinatorial probe for correlated live imaging and electron microscopy, allows identification and quantitative analysis of various cells and organelles

por Kuipers, Jeroen, van Ham, Tjakko J., Kalicharan, Ruby D., Veenstra-Algra, Anneke, Sjollema, Klaas A., Dijk, Freark, Schnell, Ulrike, Giepmans, Ben N. G.
Publicado 2015

Identification of a conserved and acute neurodegeneration‐specific microglial transcriptome in the zebrafish

por Oosterhof, Nynke, Holtman, Inge R., Kuil, Laura E., van der Linde, Herma C., Boddeke, Erik W.G.M., Eggen, Bart J.L., van Ham, Tjakko J.
Publicado 2016

Comprehensive multi-omics integration identifies differentially active enhancers during human brain development with clinical relevance

por Yousefi, Soheil, Deng, Ruizhi, Lanko, Kristina, Salsench, Eva Medico, Nikoncuk, Anita, van der Linde, Herma C., Perenthaler, Elena, van Ham, Tjakko J., Mulugeta, Eskeatnaf, Barakat, Tahsin Stefan
Publicado 2021

Intravital correlated microscopy reveals differential macrophage and microglial dynamics during resolution of neuroinflammation

por van Ham, Tjakko J., Brady, Colleen A., Kalicharan, Ruby D., Oosterhof, Nynke, Kuipers, Jeroen, Veenstra-Algra, Anneke, Sjollema, Klaas A., Peterson, Randall T., Kampinga, Harm H., Giepmans, Ben N. G.
Publicado 2014

Reduction of oxidative stress suppresses poly-GR-mediated toxicity in zebrafish embryos

por Riemslagh, Fréderike W., Verhagen, Rob F. M., van der Toorn, Esmay C., Smits, Daphne J., Quint, Wim H., van der Linde, Herma C., van Ham, Tjakko J., Willemsen, Rob
Publicado 2021

Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration

por Tsarouchas, Themistoklis M., Wehner, Daniel, Cavone, Leonardo, Munir, Tahimina, Keatinge, Marcus, Lambertus, Marvin, Underhill, Anna, Barrett, Thomas, Kassapis, Elias, Ogryzko, Nikolay, Feng, Yi, van Ham, Tjakko J., Becker, Thomas, Becker, Catherina G.
Publicado 2018

Hexb enzyme deficiency leads to lysosomal abnormalities in radial glia and microglia in zebrafish brain development

por Kuil, Laura E., López Martí, Anna, Carreras Mascaro, Ana, van den Bosch, Jeroen C., van den Berg, Paul, van der Linde, Herma C., Schoonderwoerd, Kees, Ruijter, George J. G., van Ham, Tjakko J.
Publicado 2019

Unexplained mismatch repair deficiency: Case closed

por Eikenboom, Ellis L., Moen, Sarah, van Leeuwen, Lotte, Geurts-Giele, Willemina R.R., Tops, Carli M.J., van Ham, Tjakko J., Dinjens, Winand N.M., Dubbink, Hendrikus J., Spaander, Manon C.W., Wagner, Anja
Publicado 2022

Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis

por Cunha, Maria Inês, Su, Minhui, Cantuti-Castelvetri, Ludovico, Müller, Stephan A., Schifferer, Martina, Djannatian, Minou, Alexopoulos, Ioannis, van der Meer, Franziska, Winkler, Anne, van Ham, Tjakko J., Schmid, Bettina, Lichtenthaler, Stefan F., Stadelmann, Christine, Simons, Mikael
Publicado 2020

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment

por Smits, Daphne J., Dekker, Jordy, Schot, Rachel, Tabarki, Brahim, Alhashem, Amal, Demmers, Jeroen A. A., Dekkers, Dick H. W., Romito, Antonio, van der Spek, Peter J., van Ham, Tjakko J., Bertoli-Avella, Aida M., Mancini, Grazia M. S.
Publicado 2022

Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes

por Kuil, Laura E, Oosterhof, Nynke, Ferrero, Giuliano, Mikulášová, Tereza, Hason, Martina, Dekker, Jordy, Rovira, Mireia, van der Linde, Herma C, van Strien, Paulina MH, de Pater, Emma, Schaaf, Gerben, Bindels, Erik MJ, Wittamer, Valerie, van Ham, Tjakko J
Publicado 2020

Three patients with defects in interferon gamma receptor signaling: A challenging diagnosis

por Zhou, Zijun, Hollink, Iris H. I. M., Bouman, Arjan, Lourens, Mirthe S., Brooimans, Rik A., van Ham, Tjakko J., Fraaij, Pieter L. A., van Rossum, Annemarie M. C., Zijtregtop, Eline A. M., Dik, Willem A., Dalm, Virgil A. S. H., van Hagen, P. Martin, Ijspeert, Hanna, Vermont, Clementien L.
Publicado 2022