Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia

por Aulin, Linda B. S., Kleijburg, Anne, Moerland, Matthijs, van Hasselt, J. G. Coen
Publicado 2022

Predictions of Bedaquiline and Pretomanid Target Attainment in Lung Lesions of Tuberculosis Patients using Translational Minimal Physiologically Based Pharmacokinetic Modeling

por Mehta, Krina, Guo, Tingjie, van der Graaf, Piet H., van Hasselt, J. G. Coen
Publicado 2023

Unraveling the Effects of Acute Inflammation on Pharmacokinetics: A Model-Based Analysis Focusing on Renal Glomerular Filtration Rate and Cytochrome P450 3A4-Mediated Metabolism

por Liu, Feiyan, Aulin, Linda B. S., Manson, Martijn L., Krekels, Elke H. J., van Hasselt, J. G. Coen
Publicado 2023

Clinical Pharmacokinetics and Pharmacodynamics of Immune Checkpoint Inhibitors

por Centanni, Maddalena, Moes, Dirk Jan A. R., Trocóniz, Iñaki F., Ciccolini, Joseph, van Hasselt, J. G. Coen
Publicado 2019

The status of pharmacometrics in pregnancy: highlights from the 3(rd) American conference on pharmacometrics

por van Hasselt, J G Coen, Andrew, Marilee A, Hebert, Mary F, Tarning, Joel, Vicini, Paolo, Mattison, Donald R
Publicado 2012

Design principles of collateral sensitivity-based dosing strategies

por Aulin, Linda B. S., Liakopoulos, Apostolos, van der Graaf, Piet H., Rozen, Daniel E., van Hasselt, J. G. Coen
Publicado 2021

Identification of antibiotic collateral sensitivity and resistance interactions in population surveillance data

por Zwep, Laura B, Haakman, Yob, Duisters, Kevin L W, Meulman, Jacqueline J, Liakopoulos, Apostolos, van Hasselt, J G Coen
Publicado 2021

Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy

por van Hasselt, J. G. Coen, Allegaert, Karel, van Calsteren, Kristel, Beijnen, Jos H., Schellens, Jan H. M., Huitema, Alwin D. R.
Publicado 2014

Corrigendum to “Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy”

por van Hasselt, J. G. Coen, Allegaert, Karel, van Calsteren, Kristel, Beijnen, Jos H., Schellens, Jan H. M., Huitema, Alwin D. R.
Publicado 2015

Identification of high‐dimensional omics‐derived predictors for tumor growth dynamics using machine learning and pharmacometric modeling

por Zwep, Laura B., Duisters, Kevin L. W., Jansen, Martijn, Guo, Tingjie, Meulman, Jacqueline J., Upadhyay, Parth J., van Hasselt, J. G. Coen
Publicado 2021

Biomarker‐Guided Individualization of Antibiotic Therapy

por Aulin, Linda B.S., de Lange, Dylan W., Saleh, Mohammed A.A., van der Graaf, Piet H., Völler, Swantje, van Hasselt, J.G. Coen
Publicado 2021

Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans

por Aulin, Linda B. S., Valitalo, Pyry A., Rizk, Matthew L., Visser, Sandra A. G., Rao, Gauri, van der Graaf, Piet H., van Hasselt, J. G. Coen
Publicado 2018

Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations

por Aulin, Linda B. S., Tandar, Sebastian T., van Zijp, Torben, van Ballegooie, Etienne, van der Graaf, Piet H., Saleh, Mohammed A. A., Välitalo, Pyry, van Hasselt, J. G. Coen
Publicado 2022

Crowdsourced Asparagus Urinary Odor Population Kinetics

por Ramamoorthy, Anuradha, Sadler, Brian M., van Hasselt, J.G. Coen, Elassaiss‐Schaap, Jeroen, Kasichayanula, Sreeneeranj, Edwards, Alena Y., van der Graaf, Piet H., Zhang, Lei, Wagner, John A.
Publicado 2017

A novel cardiovascular systems model to quantify drugs effects on the inter‐relationship between contractility and other hemodynamic variables

por Fu, Yu, Taghvafard, Hadi, Said, Medhat M., Rossman, Eric I., Collins, Teresa A., Billiald‐Desquand, Stéphanie, Leishman, Derek, van der Graaf, Piet H., van Hasselt, J. G. Coen, Snelder, Nelleke
Publicado 2022

Pharmacodynamic modeling of cardiac biomarkers in breast cancer patients treated with anthracycline and trastuzumab regimens

por de Vries Schultink, Aurelia H. M., Boekhout, Annelies H., Gietema, Jourik A., Burylo, Artur M., Dorlo, Thomas P. C., van Hasselt, J. G. Coen, Schellens, Jan H. M., Huitema, Alwin D. R.
Publicado 2018

Metabolomic profiling of microbial disease etiology in community-acquired pneumonia

por den Hartog, Ilona, Zwep, Laura B., Vestjens, Stefan M. T., Harms, Amy C., Voorn, G. Paul, de Lange, Dylan W., Bos, Willem J. W., Hankemeier, Thomas, van de Garde, Ewoudt M. W., van Hasselt, J. G. Coen
Publicado 2021

Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity

por van Hasselt, J. G. Coen, Rahman, Rayees, Hansen, Jens, Stern, Alan, Shim, Jaehee V., Xiong, Yuguang, Pickard, Amanda, Jayaraman, Gomathi, Hu, Bin, Mahajan, Milind, Gallo, James M., Goldfarb, Joseph, Sobie, Eric A., Birtwistle, Marc R., Schlessinger, Avner, Azeloglu, Evren U., Iyengar, Ravi
Publicado 2020

Associations Between Symptoms, Donor Characteristics and IgG Antibody Response in 2082 COVID-19 Convalescent Plasma Donors

por Vinkenoog, Marieke, Steenhuis, Maurice, Brinke, Anja ten, van Hasselt, J. G. Coen, Janssen, Mart P., van Leeuwen, Matthijs, Swaneveld, Francis H., Vrielink, Hans, van de Watering, Leo, Quee, Franke, van den Hurk, Katja, Rispens, Theo, Hogema, Boris, van der Schoot, C. Ellen
Publicado 2022

Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity

por Calizo, Rhodora C., Bhattacharya, Smiti, van Hasselt, J. G. Coen, Wei, Chengguo, Wong, Jenny S., Wiener, Robert J., Ge, Xuhua, Wong, Nicholas J., Lee, Jia-Jye, Cuttitta, Christina M., Jayaraman, Gomathi, Au, Vivienne H., Janssen, William, Liu, Tong, Li, Hong, Salem, Fadi, Jaimes, Edgar A., Murphy, Barbara, Campbell, Kirk N., Azeloglu, Evren U.
Publicado 2019