Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia

por Aulin, Linda B. S., Kleijburg, Anne, Moerland, Matthijs, van Hasselt, J. G. Coen
Publicado 2022

Predictions of Bedaquiline and Pretomanid Target Attainment in Lung Lesions of Tuberculosis Patients using Translational Minimal Physiologically Based Pharmacokinetic Modeling

por Mehta, Krina, Guo, Tingjie, van der Graaf, Piet H., van Hasselt, J. G. Coen
Publicado 2023

Unraveling the Effects of Acute Inflammation on Pharmacokinetics: A Model-Based Analysis Focusing on Renal Glomerular Filtration Rate and Cytochrome P450 3A4-Mediated Metabolism

por Liu, Feiyan, Aulin, Linda B. S., Manson, Martijn L., Krekels, Elke H. J., van Hasselt, J. G. Coen
Publicado 2023

Clinical Pharmacokinetics and Pharmacodynamics of Immune Checkpoint Inhibitors

por Centanni, Maddalena, Moes, Dirk Jan A. R., Trocóniz, Iñaki F., Ciccolini, Joseph, van Hasselt, J. G. Coen
Publicado 2019

Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution

por Liakopoulos, Apostolos, Aulin, Linda B. S., Buffoni, Matteo, Fragkiskou, Efthymia, Coen van Hasselt, J. G., Rozen, Daniel E.
Publicado 2022

The status of pharmacometrics in pregnancy: highlights from the 3(rd) American conference on pharmacometrics

por van Hasselt, J G Coen, Andrew, Marilee A, Hebert, Mary F, Tarning, Joel, Vicini, Paolo, Mattison, Donald R
Publicado 2012

Design principles of collateral sensitivity-based dosing strategies

por Aulin, Linda B. S., Liakopoulos, Apostolos, van der Graaf, Piet H., Rozen, Daniel E., van Hasselt, J. G. Coen
Publicado 2021

Identification of antibiotic collateral sensitivity and resistance interactions in population surveillance data

por Zwep, Laura B, Haakman, Yob, Duisters, Kevin L W, Meulman, Jacqueline J, Liakopoulos, Apostolos, van Hasselt, J G Coen
Publicado 2021

Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy

por van Hasselt, J. G. Coen, Allegaert, Karel, van Calsteren, Kristel, Beijnen, Jos H., Schellens, Jan H. M., Huitema, Alwin D. R.
Publicado 2014

Corrigendum to “Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy”

por van Hasselt, J. G. Coen, Allegaert, Karel, van Calsteren, Kristel, Beijnen, Jos H., Schellens, Jan H. M., Huitema, Alwin D. R.
Publicado 2015

Identification of high‐dimensional omics‐derived predictors for tumor growth dynamics using machine learning and pharmacometric modeling

por Zwep, Laura B., Duisters, Kevin L. W., Jansen, Martijn, Guo, Tingjie, Meulman, Jacqueline J., Upadhyay, Parth J., van Hasselt, J. G. Coen
Publicado 2021

Biomarker‐Guided Individualization of Antibiotic Therapy

por Aulin, Linda B.S., de Lange, Dylan W., Saleh, Mohammed A.A., van der Graaf, Piet H., Völler, Swantje, van Hasselt, J.G. Coen
Publicado 2021

Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans

por Aulin, Linda B. S., Valitalo, Pyry A., Rizk, Matthew L., Visser, Sandra A. G., Rao, Gauri, van der Graaf, Piet H., van Hasselt, J. G. Coen
Publicado 2018

Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs

por Janssen, J. M., Damoiseaux, D., van Hasselt, J. G. C., Amant, F. C. H., van Calsteren, K., Beijnen, J. H., Huitema, A. D. R., Dorlo, T. P. C.
Publicado 2023

The refined Hurley classification: the inter‐rater and intrarater reliability and face validity

por Prens, L.M., Rondags, A., Volkering, R.J., Janse, I.C., Politiek, K., Zuidema, Y.S., Turcan, I., van Hasselt, J., van der Zee, H.H., Horváth, B.
Publicado 2019

Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations

por Aulin, Linda B. S., Tandar, Sebastian T., van Zijp, Torben, van Ballegooie, Etienne, van der Graaf, Piet H., Saleh, Mohammed A. A., Välitalo, Pyry, van Hasselt, J. G. Coen
Publicado 2022

Crowdsourced Asparagus Urinary Odor Population Kinetics

por Ramamoorthy, Anuradha, Sadler, Brian M., van Hasselt, J.G. Coen, Elassaiss‐Schaap, Jeroen, Kasichayanula, Sreeneeranj, Edwards, Alena Y., van der Graaf, Piet H., Zhang, Lei, Wagner, John A.
Publicado 2017

Distinct evolution of colistin resistance associated with experimental resistance evolution models in Klebsiella pneumoniae

por Aulin, L B S, Koumans, C I M, Haakman, Y, van Os, W, Kraakman, M E M, Gooskens, J, Smits, W K, Liakopoulos, A, van Hasselt, J G C
Publicado 2020

A novel cardiovascular systems model to quantify drugs effects on the inter‐relationship between contractility and other hemodynamic variables

por Fu, Yu, Taghvafard, Hadi, Said, Medhat M., Rossman, Eric I., Collins, Teresa A., Billiald‐Desquand, Stéphanie, Leishman, Derek, van der Graaf, Piet H., van Hasselt, J. G. Coen, Snelder, Nelleke
Publicado 2022

Pharmacodynamic modeling of cardiac biomarkers in breast cancer patients treated with anthracycline and trastuzumab regimens

por de Vries Schultink, Aurelia H. M., Boekhout, Annelies H., Gietema, Jourik A., Burylo, Artur M., Dorlo, Thomas P. C., van Hasselt, J. G. Coen, Schellens, Jan H. M., Huitema, Alwin D. R.
Publicado 2018