Evaluation of a Cardiovascular Systems Model for Design and Analysis of Hemodynamic Safety Studies

por Fu, Yu, Snelder, Nelleke, Guo, Tingjie, van der Graaf, Piet H., van Hasselt, Johan. G. C.
Publicado 2023

Systematic Evaluation of the Descriptive and Predictive Performance of Paediatric Morphine Population Models

por Krekels, Elke H. J., van Hasselt, Johan G. C., Tibboel, Dick, Danhof, Meindert, Knibbe, Catherijne A. J.
Publicado 2010

A Review of Mathematical Models for Tumor Dynamics and Treatment Resistance Evolution of Solid Tumors

por Yin, Anyue, Moes, Dirk Jan A.R., van Hasselt, Johan G.C., Swen, Jesse J., Guchelaar, Henk‐Jan
Publicado 2019

Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance

por Yin, Anyue, van Hasselt, Johan G. C., Guchelaar, Henk-Jan, Friberg, Lena E., Moes, Dirk Jan A. R.
Publicado 2022

Publisher Correction: Anti-cancer treatment schedule optimization based on tumor dynamics modelling incorporating evolving resistance

por Yin, Anyue, van Hasselt, Johan G. C., Guchelaar, Henk-Jan, Friberg, Lena E., Moes, Dirk Jan A. R.
Publicado 2022

Mechanistic Systems Modeling to Improve Understanding and Prediction of Cardiotoxicity Caused by Targeted Cancer Therapeutics

por Shim, Jaehee V., Chun, Bryan, van Hasselt, Johan G. C., Birtwistle, Marc R., Saucerman, Jeffrey J., Sobie, Eric A.
Publicado 2017

Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations

por Liu, Feiyan, Aulin, Linda B. S., Guo, Tingjie, Krekels, Elke H. J., Moerland, Matthijs, van der Graaf, Piet H., van Hasselt, Johan G. C.
Publicado 2022

A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis

por Liu, Feiyan, Aulin, Linda B. S., Kossen, Sebastiaan S. A., Cathalina, Julius, Bremmer, Marlotte, Foks, Amanda C., van der Graaf, Piet H., Moerland, Matthijs, van Hasselt, Johan G. C.
Publicado 2022

Pooled Population Pharmacokinetic Analysis for Exploring Ciprofloxacin Pharmacokinetic Variability in Intensive Care Patients

por Guo, Tingjie, Abdulla, Alan, Koch, Birgit C. P., van Hasselt, Johan G. C., Endeman, Henrik, Schouten, Jeroen A., Elbers, Paul W. G., Brüggemann, Roger J. M., van Hest, Reinier M.
Publicado 2022

Zebrafish larvae as experimental model to expedite the search for new biomarkers and treatments for neonatal sepsis

por Keij, Fleur M., Koch, Bjørn E. V., Lozano Vigario, Fernando, Simons, Sinno H. P., van Hasselt, Johan G. C., Taal, H. Rob, Knibbe, C. A. J., Spaink, Herman P., Reiss, Irwin K. M., Krekels, Elke H. J.
Publicado 2021

Why we should sample sparsely and aim for a higher target: Lessons from model‐based therapeutic drug monitoring of vancomycin in intensive care patients

por Guo, Tingjie, van Hest, Reinier M., Fleuren, Lucas M., Roggeveen, Luca F., Bosman, Rob J., van der Voort, Peter H.J., Girbes, Armand R.J., Mathot, Ron A.A., van Hasselt, Johan G.C., Elbers, Paul W.G.
Publicado 2020

Correction to: Optimizing Predictive Performance of Bayesian Forecasting for Vancomycin Concentration in Intensive Care Patients

por Guo, Tingjie, van Hest, Reinier M., Zwep, Laura B., Roggeveen, Luca F., Fleuren, Lucas M., Bosman, Rob J., van der Voort, Peter H. J., Girbes, Armand R. J., Mathot, Ron A. A., Elbers, Paul W. G., van Hasselt, Johan G. C.
Publicado 2020

Optimizing Predictive Performance of Bayesian Forecasting for Vancomycin Concentration in Intensive Care Patients

por Guo, Tingjie, van Hest, Reinier M., Zwep, Laura B., Roggeveen, Luca F., Fleuren, Lucas M., Bosman, Rob J., van der Voort, Peter H. J., Girbes, Armand R. J., Mathot, Ron A. A., Elbers, Paul W. G., van Hasselt, Johan G. C.
Publicado 2020

A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations

por Yamamoto, Yumi, Välitalo, Pyry A., van den Berg, Dirk-Jan, Hartman, Robin, van den Brink, Willem, Wong, Yin Cheong, Huntjens, Dymphy R., Proost, Johannes H., Vermeulen, An, Krauwinkel, Walter, Bakshi, Suruchi, Aranzana-Climent, Vincent, Marchand, Sandrine, Dahyot-Fizelier, Claire, Couet, William, Danhof, Meindert, van Hasselt, Johan G. C., de Lange, Elizabeth C. M.
Publicado 2016

A Comparison of mRNA Sequencing with Random Primed and 3′-Directed Libraries

por Xiong, Yuguang, Soumillon, Magali, Wu, Jie, Hansen, Jens, Hu, Bin, van Hasselt, Johan G. C., Jayaraman, Gomathi, Lim, Ryan, Bouhaddou, Mehdi, Ornelas, Loren, Bochicchio, Jim, Lenaeus, Lindsay, Stocksdale, Jennifer, Shim, Jaehee, Gomez, Emilda, Sareen, Dhruv, Svendsen, Clive, Thompson, Leslie M., Mahajan, Milind, Iyengar, Ravi, Sobie, Eric A., Azeloglu, Evren U., Birtwistle, Marc R.
Publicado 2017

Effects of antibiotic resistance, drug target attainment, bacterial pathogenicity and virulence, and antibiotic access and affordability on outcomes in neonatal sepsis: an internat...

por Thomson, Kathryn M, Dyer, Calie, Liu, Feiyan, Sands, Kirsty, Portal, Edward, Carvalho, Maria J, Barrell, Matthew, Boostrom, Ian, Dunachie, Susanna, Farzana, Refath, Ferreira, Ana, Frayne, Francis, Hassan, Brekhna, Jones, Ellis, Jones, Lim, Mathias, Jordan, Milton, Rebecca, Rees, Jessica, Chan, Grace J, Bekele, Delayehu, Mahlet, Abayneh, Basu, Sulagna, Nandy, Ranjan K, Saha, Bijan, Iregbu, Kenneth, Modibbo, Fatima, Uwaezuoke, Stella, Zahra, Rabaab, Shirazi, Haider, Syed, Najeeb U, Mazarati, Jean-Baptiste, Rucogoza, Aniceth, Gaju, Lucie, Mehtar, Shaheen, Bulabula, Andre N H, Whitelaw, Andrew, van Hasselt, Johan G C, Walsh, Timothy R
Publicado 2021