Small-Molecule Inhibitors of Chikungunya Virus: Mechanisms of Action and Antiviral Drug Resistance

por Kovacikova, Kristina, van Hemert, Martijn J.
Publicado 2020

SHAPE-guided RNA structure homology search and motif discovery

por Morandi, Edoardo, van Hemert, Martijn J., Incarnato, Danny
Publicado 2022

Polyprotein Processing as a Determinant for In Vitro Activity of Semliki Forest Virus Replicase

por Pietilä, Maija K., Albulescu, Irina C., van Hemert, Martijn J., Ahola, Tero
Publicado 2017

Host Factors in Coronavirus Replication

por de Wilde, Adriaan H., Snijder, Eric J., Kikkert, Marjolein, van Hemert, Martijn J.
Publicado 2017

Honokiol Inhibits SARS-CoV-2 Replication in Cell Culture at a Post-Entry Step

por Salgado-Benvindo, Clarisse, Leijs, Anouk A., Thaler, Melissa, Tas, Ali, Arbiser, Jack L., Snijder, Eric J., van Hemert, Martijn J.
Publicado 2023

SARS-Coronavirus Replication/Transcription Complexes Are Membrane-Protected and Need a Host Factor for Activity In Vitro

por van Hemert, Martijn J., van den Worm, Sjoerd H. E., Knoops, Kèvin, Mommaas, A. Mieke, Gorbalenya, Alexander E., Snijder, Eric J.
Publicado 2008

R-Propranolol Has Broad-Spectrum Anti-Coronavirus Activity and Suppresses Factors Involved in Pathogenic Angiogenesis

por Thaler, Melissa, Salgado-Benvindo, Clarisse, Leijs, Anouk, Tas, Ali, Ninaber, Dennis K., Arbiser, Jack L., Snijder, Eric J., van Hemert, Martijn J.
Publicado 2023

Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation

por Dirmeier, Simon, Dächert, Christopher, van Hemert, Martijn, Tas, Ali, Ogando, Natacha S., van Kuppeveld, Frank, Bartenschlager, Ralf, Kaderali, Lars, Binder, Marco, Beerenwinkel, Niko
Publicado 2020

Zn(2+) Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture

por te Velthuis, Aartjan J. W., van den Worm, Sjoerd H. E., Sims, Amy C., Baric, Ralph S., Snijder, Eric J., van Hemert, Martijn J.
Publicado 2010

Characterization of Synthetic Chikungunya Viruses Based on the Consensus Sequence of Recent E1-226V Isolates

por Scholte, Florine E. M., Tas, Ali, Martina, Byron E. E., Cordioli, Paolo, Narayanan, Krishna, Makino, Shinji, Snijder, Eric J., van Hemert, Martijn J.
Publicado 2013

The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling

por Treffers, Emmely E., Tas, Ali, Scholte, Florine E. M., de Ru, Arnoud H., Snijder, Eric J., van Veelen, Peter A., van Hemert, Martijn J.
Publicado 2023

Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies

por Zitzmann, Carolin, Dächert, Christopher, Schmid, Bianca, van der Schaar, Hilde, van Hemert, Martijn, Perelson, Alan S., van Kuppeveld, Frank J. M., Bartenschlager, Ralf, Binder, Marco, Kaderali, Lars
Publicado 2023

Quasispecies composition and evolution of a typical Zika virus clinical isolate from Suriname

por van Boheemen, Sander, Tas, Ali, Anvar, S. Yahya, van Grootveld, Rebecca, Albulescu, Irina C., Bauer, Martijn P., Feltkamp, Mariet C., Bredenbeek, Peter J., van Hemert, Martijn J.
Publicado 2017

Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle

por Salgado-Benvindo, Clarisse, Thaler, Melissa, Tas, Ali, Ogando, Natacha S., Bredenbeek, Peter J., Ninaber, Dennis K., Wang, Ying, Hiemstra, Pieter S., Snijder, Eric J., van Hemert, Martijn J.
Publicado 2020

Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies

por Zitzmann, Carolin, Dächert, Christopher, Schmid, Bianca, van der Schaar, Hilde, van Hemert, Martijn, Perelson, Alan S., van Kuppeveld, Frank J.M., Bartenschlager, Ralf, Binder, Marco, Kaderali, Lars
Publicado 2022

Suramin Inhibits Chikungunya Virus Replication by Interacting with Virions and Blocking the Early Steps of Infection

por Albulescu, Irina C., White-Scholten, Leonie, Tas, Ali, Hoornweg, Tabitha E., Ferla, Salvatore, Kovacikova, Kristina, Smit, Jolanda M., Brancale, Andrea, Snijder, Eric J., van Hemert, Martijn J.
Publicado 2020

Tomatidine reduces Chikungunya virus progeny release by controlling viral protein expression

por Troost-Kind, Berit, van Hemert, Martijn J., van de Pol, Denise, van der Ende-Metselaar, Heidi, Merits, Andres, Borggrewe, Malte, Rodenhuis-Zybert, Izabela A., Smit, Jolanda M.
Publicado 2021

Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements

por Manfredonia, Ilaria, Nithin, Chandran, Ponce-Salvatierra, Almudena, Ghosh, Pritha, Wirecki, Tomasz K, Marinus, Tycho, Ogando, Natacha S, Snijder, Eric J, van Hemert, Martijn J, Bujnicki, Janusz M, Incarnato, Danny
Publicado 2020

SARS-CoV-2-specific CD4(+) and CD8(+) T cell responses can originate from cross-reactive CMV-specific T cells

por Pothast, Cilia R, Dijkland, Romy C, Thaler, Melissa, Hagedoorn, Renate S, Kester, Michel GD, Wouters, Anne K, Hiemstra, Pieter S, van Hemert, Martijn J, Gras, Stephanie, Falkenburg, JH Frederik, Heemskerk, Mirjam HM
Publicado 2022

The Cyclophilin-Dependent Calcineurin Inhibitor Voclosporin Inhibits SARS-CoV-2 Replication in Cell Culture

por Ogando, Natacha S., Metscher, Erik, Moes, Dirk Jan A. R., Arends, Eline J., Tas, Ali, Cross, Jennifer, Snijder, Eric J., Teng, Y. K. Onno, de Vries, Aiko P. J., van Hemert, Martijn J.
Publicado 2022