Adaptable gene-specific dye bias correction for two-channel DNA microarrays

por Margaritis, Thanasis, Lijnzaad, Philip, van Leenen, Dik, Bouwmeester, Diane, Kemmeren, Patrick, van Hooff, Sander R, Holstege, Frank CP
Publicado 2009

Tight cooperation between Mot1p and NC2β in regulating genome-wide transcription, repression of transcription following heat shock induction and genetic interaction with SAGA

por Spedale, Gianpiero, Meddens, Claartje A., Koster, Maria J. E., Ko, Cheuk W., van Hooff, Sander R., Holstege, Frank C. P., Timmers, H. Th. Marc, Pijnappel, W. W. M. Pim
Publicado 2012

AKT3 Expression in Mesenchymal Colorectal Cancer Cells Drives Growth and Is Associated with Epithelial-Mesenchymal Transition

por Buikhuisen, Joyce Y., Gomez Barila, Patricia M., Torang, Arezo, Dekker, Daniëlle, de Jong, Joan H., Cameron, Kate, Vitale, Sara, Stassi, Giorgio, van Hooff, Sander R., Castro, Mauro A. A., Vermeulen, Louis, Medema, Jan Paul
Publicado 2021

Capturing colorectal cancer inter‐tumor heterogeneity in patient‐derived xenograft (PDX) models

por Prasetyanti, Pramudita R., van Hooff, Sander R., van Herwaarden, Tessa, de Vries, Nathalie, Kalloe, Kieshen, Rodermond, Hans, van Leersum, Ronald, de Jong, Joan H., Franitza, Marek, Nürnberg, Peter, Todaro, Matilde, Stassi, Giorgio, Medema, Jan Paul
Publicado 2018

An endometrial gene expression signature accurately predicts recurrent implantation failure after IVF

por Koot, Yvonne E. M., van Hooff, Sander R., Boomsma, Carolien M., van Leenen, Dik, Groot Koerkamp, Marian J. A., Goddijn, Mariëtte, Eijkemans, Marinus J. C., Fauser, Bart C. J. M., Holstege, Frank C. P., Macklon, Nick S.
Publicado 2016

Two opposing gene expression patterns within ATRX aberrant neuroblastoma

por van Gerven, Michael R., Schild, Linda, van Arkel, Jennemiek, Koopmans, Bianca, Broeils, Luuk A., Meijs, Loes A. M., van Oosterhout, Romy, van Noesel, Max M., Koster, Jan, van Hooff, Sander R., Molenaar, Jan J., van den Boogaard, Marlinde L.
Publicado 2023

A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions

por Sameith, Katrin, Amini, Saman, Groot Koerkamp, Marian J. A., van Leenen, Dik, Brok, Mariel, Brabers, Nathalie, Lijnzaad, Philip, van Hooff, Sander R., Benschop, Joris J., Lenstra, Tineke L., Apweiler, Eva, van Wageningen, Sake, Snel, Berend, Holstege, Frank C. P., Kemmeren, Patrick
Publicado 2015

αβ-T Cells Engineered to Express γδ-T Cell Receptors Can Kill Neuroblastoma Organoids Independent of MHC-I Expression

por Strijker, Josephine G. M., Pscheid, Ronja, Drent, Esther, van der Hoek, Jessica J. F., Koopmans, Bianca, Ober, Kimberley, van Hooff, Sander R., Kholosy, Waleed M., Cornel, Annelisa M., Coomans, Chris, Bisso, Andrea, van Loenen, Marleen M., Molenaar, Jan J., Wienke, Judith
Publicado 2021

Exploring Gene Expression Signatures for Predicting Disease Free Survival after Resection of Colorectal Cancer Liver Metastases

por Snoeren, Nikol, van Hooff, Sander R., Adam, Rene, van Hillegersberg, Richard, Voest, Emile E., Guettier, Catherine, van Diest, Paul J., Nijkamp, Maarten W., Brok, Mariel O., van Leenen, Dik, Groot Koerkamp, Marian J. A., Holstege, Frank C. P., Borel Rinkes, Inne H. M.
Publicado 2012

TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype

por Fessler, Evelyn, Drost, Jarno, van Hooff, Sander R, Linnekamp, Janneke F, Wang, Xin, Jansen, Marnix, De Sousa E Melo, Felipe, Prasetyanti, Pramudita R, IJspeert, Joep EG, Franitza, Marek, Nürnberg, Peter, van Noesel, Carel JM, Dekker, Evelien, Vermeulen, Louis, Clevers, Hans, Medema, Jan Paul
Publicado 2016

BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer

por Ramesh, Prashanthi, Lannagan, Tamsin R. M., Jackstadt, Rene, Atencia Taboada, Lidia, Lansu, Nico, Wirapati, Pratyaksha, van Hooff, Sander R., Dekker, Danielle, Pritchard, Jessica, Kirov, Aleksandar B., van Neerven, Sanne M., Tejpar, Sabine, Kops, Geert J. P. L., Sansom, Owen J., Medema, Jan Paul
Publicado 2021

Chromosome 11q loss and MYCN amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma

por Keller, Kaylee M., Eleveld, Thomas F., Schild, Linda, van den Handel, Kim, van den Boogaard, Marlinde, Amo-Addae, Vicky, Eising, Selma, Ober, Kimberley, Koopmans, Bianca, Looijenga, Leendert, Tytgat, Godelieve A.M., Ylstra, Bauke, Molenaar, Jan J., Dolman, M. Emmy M., van Hooff, Sander R.
Publicado 2022

The potential of PARP as a therapeutic target across pediatric solid malignancies

por Keller, Kaylee M., Koetsier, Joost, Schild, Linda, Amo-Addae, Vicky, Eising, Selma, van den Handel, Kim, Ober, Kimberley, Koopmans, Bianca, Essing, Anke, van den Boogaard, Marlinde L., Langenberg, Karin P. S., Jäger, Natalie, Kool, Marcel, Pfister, Stefan, Dolman, M. Emmy M., Molenaar, Jan J., van Hooff, Sander R.
Publicado 2023

Effective methods for bulk RNA-seq deconvolution using scnRNA-seq transcriptomes

por Cobos, Francisco Avila, Panah, Mohammad Javad Najaf, Epps, Jessica, Long, Xiaochen, Man, Tsz-Kwong, Chiu, Hua-Sheng, Chomsky, Elad, Kiner, Evgeny, Krueger, Michael J., di Bernardo, Diego, Voloch, Luis, Molenaar, Jan, van Hooff, Sander R., Westermann, Frank, Jansky, Selina, Redell, Michele L., Mestdagh, Pieter, Sumazin, Pavel
Publicado 2023

Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

por Jackstadt, Rene, van Hooff, Sander R., Leach, Joshua D., Cortes-Lavaud, Xabier, Lohuis, Jeroen O., Ridgway, Rachel A., Wouters, Valérie M., Roper, Jatin, Kendall, Timothy J., Roxburgh, Campbell S., Horgan, Paul G., Nixon, Colin, Nourse, Craig, Gunzer, Matthias, Clark, William, Hedley, Ann, Yilmaz, Omer H., Rashid, Mamunur, Bailey, Peter, Biankin, Andrew V., Campbell, Andrew D., Adams, David J., Barry, Simon T., Steele, Colin W., Medema, Jan Paul, Sansom, Owen J.
Publicado 2019

Unsupervised class discovery in pancreatic ductal adenocarcinoma reveals cell-intrinsic mesenchymal features and high concordance between existing classification systems

por Dijk, Frederike, Veenstra, Veronique L., Soer, Eline C., Dings, Mark P. G., Zhao, Lan, Halfwerk, Johannes B., Hooijer, Gerrit K., Damhofer, Helene, Marzano, Marco, Steins, Anne, Waasdorp, Cynthia, Busch, Olivier R., Besselink, Marc G., Tol, Johanna A., Welling, Lieke, van Rijssen, Lennart B., Klompmaker, Sjors, Wilmink, Hanneke W., van Laarhoven, Hanneke W., Medema, Jan Paul, Vermeulen, Louis, van Hooff , Sander R., Koster, Jan, Verheij, Joanne, van de Vijver, Marc J., Wang, Xin, Bijlsma, Maarten F.
Publicado 2020

Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis

por Leach, Joshua D. G., Vlahov, Nikola, Tsantoulis, Petros, Ridgway, Rachel A., Flanagan, Dustin J., Gilroy, Kathryn, Sphyris, Nathalie, Vázquez, Ester G., Vincent, David F., Faller, William J., Hodder, Michael C., Raven, Alexander, Fey, Sigrid, Najumudeen, Arafath K., Strathdee, Douglas, Nixon, Colin, Hughes, Mark, Clark, William, Shaw, Robin, van Hooff, Sander R., Huels, David J., Medema, Jan Paul, Barry, Simon T., Frame, Margaret C., Unciti-Broceta, Asier, Leedham, Simon J., Inman, Gareth J., Jackstadt, Rene, Thompson, Barry J., Campbell, Andrew D., Tejpar, Sabine, Sansom, Owen J.
Publicado 2021

Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell

por Kildisiute, Gerda, Kholosy, Waleed M., Young, Matthew D., Roberts, Kenny, Elmentaite, Rasa, van Hooff, Sander R., Pacyna, Clarissa N., Khabirova, Eleonora, Piapi, Alice, Thevanesan, Christine, Bugallo-Blanco, Eva, Burke, Christina, Mamanova, Lira, Keller, Kaylee M., Langenberg-Ververgaert, Karin P.S., Lijnzaad, Philip, Margaritis, Thanasis, Holstege, Frank C.P., Tas, Michelle L., Wijnen, Marc H.W.A., van Noesel, Max M., del Valle, Ignacio, Barone, Giuseppe, van der Linden, Reinier, Duncan, Catriona, Anderson, John, Achermann, John C., Haniffa, Muzlifah, Teichmann, Sarah A., Rampling, Dyanne, Sebire, Neil J., He, Xiaoling, de Krijger, Ronald R., Barker, Roger A., Meyer, Kerstin B., Bayraktar, Omer, Straathof, Karin, Molenaar, Jan J., Behjati, Sam
Publicado 2021

Implementation of paediatric precision oncology into clinical practice: The Individualized Therapies for Children with cancer program ‘iTHER’

por Langenberg, Karin P.S., Meister, Michael T., Bakhuizen, Jette J., Boer, Judith M., van Eijkelenburg, Natasha K.A., Hulleman, Esther, Ilan, Uri, Looze, Eleonora J., Dierselhuis, Miranda P., van der Lugt, Jasper, Breunis, Willemijn, Schild, Linda G., Ober, Kimberley, van Hooff, Sander R., Scheijde-Vermeulen, Marijn A., Hiemcke-Jiwa, Laura S., Flucke, Uta E., Kranendonk, Mariette E.G., Wesseling, Pieter, Sonneveld, Edwin, Punt, Simone, Boltjes, Arjan, van Dijk, Freerk, Verwiel, Eugene T.P., Volckmann, Richard, Hehir-Kwa, Jayne Y., Kester, Lennart A., Koudijs, Marco M.J., Waanders, Esme, Holstege, Frank C.P., Vormoor, H. Josef, Hoving, Eelco W., van Noesel, Max M., Pieters, Rob, Kool, Marcel, Stumpf, Miriam, Blattner-Johnson, Mirjam, Balasubramanian, Gnana P., Van Tilburg, Cornelis M., Jones, Barbara C., Jones, David T.W., Witt, Olaf, Pfister, Stefan M., Jongmans, Marjolijn C.J., Kuiper, Roland P., de Krijger, Ronald R., Wijnen, Marc H.W., den Boer, Monique L., Zwaan, C. Michel, Kemmeren, Patrick, Koster, Jan, Tops, Bastiaan B.J., Goemans, Bianca F., Molenaar, Jan J.
Publicado 2022