Targeted Deletion of Btg1 and Btg2 Results in Homeotic Transformation of the Axial Skeleton

por Tijchon, Esther, van Ingen Schenau, Dorette, van Opzeeland, Fred, Tirone, Felice, Hoogerbrugge, Peter M., Van Leeuwen, Frank N., Scheijen, Blanca
Publicado 2015

Reversal of IKZF1-induced glucocorticoid resistance by dual targeting of AKT and ERK signaling pathways

por Butler, Miriam, Vervoort, Britt M.T., van Ingen Schenau, Dorette S., Jongeneel, Lieneke, van der Zwet, Jordy C.G., Marke, René, Meijerink, Jules P.P., Scheijen, Blanca, van der Meer, Laurens T., van Leeuwen, Frank N.
Publicado 2022

Tumor suppressor BTG1 promotes PRMT1-mediated ATF4 function in response to cellular stress

por Yuniati, Laurensia, van der Meer, Laurens T., Tijchon, Esther, van Ingen Schenau, Dorette, van Emst, Liesbeth, Levers, Marloes, Palit, Sander A.L., Rodenbach, Caroline, Poelmans, Geert, Hoogerbrugge, Peter M., Shan, Jixiu, Kilberg, Michael S., Scheijen, Blanca, van Leeuwen, Frank N.
Publicado 2015

Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade

por Woess, Katharina, Macho-Maschler, Sabine, van Ingen Schenau, Dorette S., Butler, Miriam, Lassnig, Caroline, Valcanover, Daniel, Poelzl, Andrea, Meissl, Katrin, Maurer, Barbara, Brandstoetter, Tania, Vogl, Claus, Koren, Anna, Kubicek, Stefan, Orlova, Anna, Moriggl, Richard, Strobl, Birgit, Sexl, Veronika, van Leeuwen, Frank N., Kuiper, Roland P., Mueller, Mathias
Publicado 2022

Human CD34(+)-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8(+) T cell and NK cell responses in vitro and in vivo

por van Eck van der Sluijs, Jesper, van Ens, Diede, Brummelman, Jolanda, Heister, Daan, Sareen, Aastha, Truijen, Lisa, van Ingen Schenau, Dorette S., Heemskerk, Mirjam H. M., Griffioen, Marieke, Kester, Michel G. D., Schaap, Nicolaas P. M., Jansen, Joop H., van der Waart, Anniek B., Dolstra, Harry, Hobo, Willemijn
Publicado 2023

BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway

por Butler, Miriam, van Ingen Schenau, Dorette S., Yu, Jiangyan, Jenni, Silvia, Dobay, Maria P., Hagelaar, Rico, Vervoort, Britt M. T., Tee, Trisha M., Hoff, Fieke W., Meijerink, Jules P., Kornblau, Steven M., Bornhauser, Beat, Bourquin, Jean-Pierre, Kuiper, Roland P., van der Meer, Laurens T., van Leeuwen, Frank N.
Publicado 2021

Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients

por Scheijen, Blanca, Boer, Judith M., Marke, René, Tijchon, Esther, van Ingen Schenau, Dorette, Waanders, Esmé, van Emst, Liesbeth, van der Meer, Laurens T., Pieters, Rob, Escherich, Gabriele, Horstmann, Martin A., Sonneveld, Edwin, Venn, Nicola, Sutton, Rosemary, Dalla-Pozza, Luciano, Kuiper, Roland P., Hoogerbrugge, Peter M., den Boer, Monique L., van Leeuwen, Frank N.
Publicado 2017