First‐in‐human trial to assess safety, tolerability, pharmacokinetics, and pharmacodynamics of zagociguat (CY6463), a CNS‐penetrant soluble guanylyl cyclase stimulator

por van Kraaij, Sebastiaan J. W., Gal, Pim, Borghans, Laura G. J. M., Klaassen, Erica S., Dijkstra, Francis, Winrow, Christopher, Glasser, Chad, Groeneveld, Geert Jan
Publicado 2023

Safety of low-volume PEG-asc bowel cleansing preparation for colonoscopy: identifying patients at risk for hypokalemia in a prospective cohort study

por Reumkens, Ankie, Bakker, Christine Minke, van Kraaij, Sebastiaan J.W., Winkens, Bjorn, Raijmakers, Maarten T., van Nunen, Annick B., van Deursen, Cees Th.B.M., Masclee, Ad A.M.
Publicado 2021

Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease

por van Kraaij, Sebastiaan J. W., Pereira, Diana R., Smal, Bastiaan, Summo, Luciana, Konkel, Anne, Lossie, Janine, Busjahn, Andreas, Grammatopoulos, Tom N., Klaassen, Erica, Fischer, Robert, Schunck, Wolf‐Hagen, Gal, Pim, Moerland, Matthijs
Publicado 2023

Immunosuppression by hydroxychloroquine: mechanistic proof in in vitro experiments but limited systemic activity in a randomized placebo-controlled clinical pharmacology study

por in ‘t Veld, Aliede E., Grievink, Hendrika W., van der Plas, Johan L., Eveleens Maarse, Boukje C., van Kraaij, Sebastiaan J. W., Woutman, Tess D., Schoonakker, Mascha, Klarenbeek, Naomi B., de Kam, Marieke L., Kamerling, Ingrid M. C., Jansen, Manon A. A., Moerland, Matthijs
Publicado 2023