Meta-analysis of dispensable essential genes and their interactions with bypass suppressors

por Pons, Carles, van Leeuwen, Jolanda
Publicado 2023

Yeast Aim21/Tda2 both regulates free actin by reducing barbed end assembly and forms a complex with Cap1/Cap2 to balance actin assembly between patches and cables

por Shin, Myungjoo, van Leeuwen, Jolanda, Boone, Charles, Bretscher, Anthony
Publicado 2018

Global analysis of suppressor mutations that rescue human genetic defects

por Ünlü, Betül, Pons, Carles, Ho, Uyen Linh, Batté, Amandine, Aloy, Patrick, van Leeuwen, Jolanda
Publicado 2023

The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae

por Huseinovic, Angelina, van Leeuwen, Jolanda S., van Welsem, Tibor, Stulemeijer, Iris, van Leeuwen, Fred, Vermeulen, Nico P. E., Kooter, Jan M., Vos, J. Chris
Publicado 2017

Chl1 helicase controls replication fork progression by regulating dNTP pools

por Batté, Amandine, van der Horst, Sophie C, Tittel-Elmer, Mireille, Sun, Su Ming, Sharma, Sushma, van Leeuwen, Jolanda, Chabes, Andrei, van Attikum, Haico
Publicado 2022

Predicting base editing outcomes using position-specific sequence determinants

por Pallaseni, Ananth, Peets, Elin Madli, Koeppel, Jonas, Weller, Juliane, Vanderstichele, Thomas, Ho, Uyen Linh, Crepaldi, Luca, van Leeuwen, Jolanda, Allen, Felicity, Parts, Leopold
Publicado 2022

Natural variants suppress mutations in hundreds of essential genes

por Parts, Leopold, Batté, Amandine, Lopes, Maykel, Yuen, Michael W, Laver, Meredith, San Luis, Bryan‐Joseph, Yue, Jia‐Xing, Pons, Carles, Eray, Elise, Aloy, Patrick, Liti, Gianni, van Leeuwen, Jolanda
Publicado 2021

Systematic analysis of bypass suppression of essential genes

por van Leeuwen, Jolanda, Pons, Carles, Tan, Guihong, Wang, Jason Zi, Hou, Jing, Weile, Jochen, Gebbia, Marinella, Liang, Wendy, Shuteriqi, Ermira, Li, Zhijian, Lopes, Maykel, Ušaj, Matej, Dos Santos Lopes, Andreia, van Lieshout, Natascha, Myers, Chad L, Roth, Frederick P, Aloy, Patrick, Andrews, Brenda J, Boone, Charles
Publicado 2020

Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens

por Hart, Traver, Tong, Amy Hin Yan, Chan, Katie, Van Leeuwen, Jolanda, Seetharaman, Ashwin, Aregger, Michael, Chandrashekhar, Megha, Hustedt, Nicole, Seth, Sahil, Noonan, Avery, Habsid, Andrea, Sizova, Olga, Nedyalkova, Lyudmila, Climie, Ryan, Tworzyanski, Leanne, Lawson, Keith, Sartori, Maria Augusta, Alibeh, Sabriyeh, Tieu, David, Masud, Sanna, Mero, Patricia, Weiss, Alexander, Brown, Kevin R., Usaj, Matej, Billmann, Maximilian, Rahman, Mahfuzur, Costanzo, Michael, Myers, Chad L., Andrews, Brenda J., Boone, Charles, Durocher, Daniel, Moffat, Jason
Publicado 2017

Functional Annotation of Chemical Libraries across Diverse Biological Processes

por Piotrowski, Jeff S., Li, Sheena C., Deshpande, Raamesh, Simpkins, Scott W., Nelson, Justin, Yashiroda, Yoko, Barber, Jacqueline M., Safizadeh, Hamid, Wilson, Erin, Okada, Hiroki, Gebre, Abraham A., Kubo, Karen, Torres, Nikko P., LeBlanc, Marissa A., Andrusiak, Kerry, Okamoto, Reika, Yoshimura, Mami, DeRango-Adem, Eva, van Leeuwen, Jolanda, Shirahige, Katsuhiko, Baryshnikova, Anastasia, Brown, Grant W., Hirano, Hiroyuki, Costanzo, Michael, Andrews, Brenda, Ohya, Yoshikazu, Osada, Hiroyuki, Yoshida, Minoru, Myers, Chad L., Boone, Charles
Publicado 2017