Extracellular Domains of CD8α and CD8ß Subunits Are Sufficient for HLA Class I Restricted Helper Functions of TCR-Engineered CD4(+) T Cells

por van Loenen, Marleen M., Hagedoorn, Renate S., de Boer, Renate, Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M.
Publicado 2013

T cell receptor engineering of primary NK cells to therapeutically target tumors and tumor immune evasion

por Morton, Laura T, Wachsmann, Tassilo L A, Meeuwsen, Miranda H, Wouters, Anne K, Remst, Dennis F G, van Loenen, Marleen M, Falkenburg, J H Frederik, Heemskerk, Mirjam H M
Publicado 2022

T cells expanded from renal cell carcinoma display tumor-specific CD137 expression but lack significant IFN-γ, TNF-α or IL-2 production

por van Asten, Saskia D., de Groot, Rosa, van Loenen, Marleen M., Castenmiller, Suzanne M., de Jong, Jeroen, Monkhorst, Kim, Haanen, John B.A.G., Amsen, Derk, Bex, Axel, Spaapen, Robbert M., Wolkers, Monika C.
Publicado 2021

αβ-T Cells Engineered to Express γδ-T Cell Receptors Can Kill Neuroblastoma Organoids Independent of MHC-I Expression

por Strijker, Josephine G. M., Pscheid, Ronja, Drent, Esther, van der Hoek, Jessica J. F., Koopmans, Bianca, Ober, Kimberley, van Hooff, Sander R., Kholosy, Waleed M., Cornel, Annelisa M., Coomans, Chris, Bisso, Andrea, van Loenen, Marleen M., Molenaar, Jan J., Wienke, Judith
Publicado 2021

HA-1H T-Cell Receptor Gene Transfer to Redirect Virus-Specific T Cells for Treatment of Hematological Malignancies After Allogeneic Stem Cell Transplantation: A Phase 1 Clinical St...

por van Balen, Peter, Jedema, Inge, van Loenen, Marleen M., de Boer, Renate, van Egmond, H. M., Hagedoorn, Renate S., Hoogstaten, Conny, Veld, Sabrina A. J., Hageman, Lois, van Liempt, P. A. G., Zwaginga, Jaap-Jan, Meij, Pauline, Veelken, H., Falkenburg, J. H. F., Heemskerk, Mirjam H. M.
Publicado 2020

Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile

por De Groot, Rosa, Van Loenen, Marleen M., Guislain, Aurélie, Nicolet, Benoît P., Freen-Van Heeren, Julian J., Verhagen, Onno J.H.M., Van Den Heuvel, Michel M., De Jong, Jeroen, Burger, Patrick, Van Der Schoot, C.Ellen, Spaapen, Robbert M., Amsen, Derk, Haanen, John B. A. G., Monkhorst, Kim, Hartemink, Koen J., Wolkers, Monika C.
Publicado 2019