Transcriptional Regulation of Channelopathies in Genetic and Acquired Epilepsies

por van Loo, Karen M. J., Becker, Albert J.
Publicado 2020

Identification of Genetic and Epigenetic Variations in a Rat Model for Neurodevelopmental Disorders

por van Loo, Karen M. J., Martens, Gerard J. M.
Publicado 2007

A Versatile Clustered Regularly Interspaced Palindromic Repeats Toolbox to Study Neurological Ca(V)3.2 Channelopathies by Promoter-Mediated Transcription Control

por Tsortouktzidis, Despina, Tröscher, Anna R., Schulz, Herbert, Opitz, Thoralf, Schoch, Susanne, Becker, Albert J., van Loo, Karen M. J.
Publicado 2022

Rats that differentially respond to cocaine differ in their dopaminergic storage capacity of the nucleus accumbens

por Verheij, Michel M M, de Mulder, Eric L W, De Leonibus, Elvira, van Loo, Karen M J, Cools, Alexander R
Publicado 2008

Neurochemical Profile of BRAF(V600E)/Akt(T308D/S473D) Mouse Gangliogliomas Reveals Impaired GABAergic System Inhibition

por Kyriazi, Maria, Müller, Philipp, Pitsch, Julika, van Loo, Karen M.J., Quatraccioni, Anne, Opitz, Thoralf, Schoch, Susanne, Becker, Albert J., Cases-Cunillera, Silvia
Publicado 2022

Male-Specific Association between a γ-Secretase Polymorphism and Premature Coronary Atherosclerosis

por van Loo, Karen M. J., Dejaegere, Tim, van Zweeden, Martine, van Schijndel, Jessica E., Wijmenga, Cisca, Trip, Mieke D., Martens, Gerard J. M.
Publicado 2008

Heterogeneity and excitability of BRAF(V600E)-induced tumors is determined by Akt/mTOR-signaling state and Trp53-loss

por Cases-Cunillera, Silvia, van Loo, Karen M J, Pitsch, Julika, Quatraccioni, Anne, Sivalingam, Sugirthan, Salomoni, Paolo, Borger, Valeri, Dietrich, Dirk, Schoch, Susanne, Becker, Albert J
Publicado 2021

Zinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1

por van Loo, Karen M. J., Schaub, Christina, Pitsch, Julika, Kulbida, Rebecca, Opitz, Thoralf, Ekstein, Dana, Dalal, Adam, Urbach, Horst, Beck, Heinz, Yaari, Yoel, Schoch, Susanne, Becker, Albert J.
Publicado 2015

Evidence of a pathogenic role for CD8(+) T cells in anti-GABA(B) receptor limbic encephalitis

por Golombeck, Kristin S., Bönte, Kathrin, Mönig, Constanze, van Loo, Karen M., Hartwig, Marvin, Schwindt, Wolfram, Widman, Guido, Lindenau, Matthias, Becker, Albert J., Glatzel, Markus, Elger, Christian E., Wiendl, Heinz, Meuth, Sven G., Lohmann, Hubertus, Gross, Catharina C., Melzer, Nico
Publicado 2016

DNA Methylation-Mediated Modulation of Endocytosis as Potential Mechanism for Synaptic Function Regulation in Murine Inhibitory Cortical Interneurons

por Pensold, Daniel, Reichard, Julia, Van Loo, Karen M J, Ciganok, Natalja, Hahn, Anne, Bayer, Cathrin, Liebmann, Lutz, Groß, Jonas, Tittelmeier, Jessica, Lingner, Thomas, Salinas-Riester, Gabriela, Symmank, Judit, Halfmann, Claas, González-Bermúdez, Lourdes, Urbach, Anja, Gehrmann, Julia, Costa, Ivan, Pieler, Tomas, Hübner, Christian A, Vatter, Hartmut, Kampa, Björn, Becker, Albert J, Zimmer-Bensch, Geraldine
Publicado 2020

SCN1A overexpression, associated with a genomic region marked by a risk variant for a common epilepsy, raises seizure susceptibility

por Silvennoinen, Katri, Gawel, Kinga, Tsortouktzidis, Despina, Pitsch, Julika, Alhusaini, Saud, van Loo, Karen M. J., Picardo, Richard, Michalak, Zuzanna, Pagni, Susanna, Martins Custodio, Helena, Mills, James, Whelan, Christopher D., de Zubicaray, Greig I., McMahon, Katie L., van der Ent, Wietske, Kirstein-Smardzewska, Karolina J., Tiraboschi, Ettore, Mudge, Jonathan M., Frankish, Adam, Thom, Maria, Wright, Margaret J., Thompson, Paul M., Schoch, Susanne, Becker, Albert J., Esguerra, Camila V., Sisodiya, Sanjay M.
Publicado 2022

Translational imaging of TSPO reveals pronounced innate inflammation in human and murine CD8 T cell–mediated limbic encephalitis

por Gallus, Marco, Roll, Wolfgang, Dik, Andre, Barca, Cristina, Zinnhardt, Bastian, Hicking, Gordon, Mueller, Christoph, Naik, Venu Narayanan, Anstötz, Max, Krämer, Julia, Rolfes, Leoni, Wachsmuth, Lydia, Pitsch, Julika, van Loo, Karen M. J., Räuber, Saskia, Okada, Hideho, Wimberley, Catriona, Strippel, Christine, Golombeck, Kristin S., Johnen, Andreas, Kovac, Stjepana, Groß, Catharina C., Backhaus, Philipp, Seifert, Robert, Lewerenz, Jan, Surges, Rainer, Elger, Christian E., Wiendl, Heinz, Ruck, Tobias, Becker, Albert J., Faber, Cornelius, Jacobs, Andreas H., Bauer, Jan, Meuth, Sven G., Schäfers, Michael, Melzer, Nico
Publicado 2023