B and T Cells Driving Multiple Sclerosis: Identity, Mechanisms and Potential Triggers

por van Langelaar, Jamie, Rijvers, Liza, Smolders, Joost, van Luijn, Marvin M.
Publicado 2020

T-cell surveillance of the human brain in health and multiple sclerosis

por Smolders, Joost, van Luijn, Marvin M., Hsiao, Cheng-Chih, Hamann, Jörg
Publicado 2022

Tumor immune escape in acute myeloid leukemia: Class II-associated invariant chain peptide expression as result of deficient antigen presentation

por van Luijn, Marvin M., Chamuleau, Martine E.D., Ossenkoppele, Gert J., van de Loosdrecht, Arjan A., Marieke van Ham, S.
Publicado 2012

Improving Glucocorticoid Sensitivity of Brain-Homing CD4(+) T Helper Cells by Steroid Hormone Crosstalk

por Koetzier, Steven C., van Langelaar, Jamie, Wierenga-Wolf, Annet F., Melief, Marie-José, Pol, Kim, Musters, Suzanne, Lubberts, Erik, Dik, Willem A., Smolders, Joost, van Luijn, Marvin M.
Publicado 2022

Multiple sclerosis risk variants influence the peripheral B‐cell compartment early in life in the general population

por de Mol, Casper L., van Luijn, Marvin M., Kreft, Karim L., Looman, Kirsten I. M., van Zelm, Menno C., White, Tonya, Moll, Henriette A., Smolders, Joost, Neuteboom, Rinze F.
Publicado 2022

Targeting Toll-like receptor 7/8 enhances uptake of apoptotic leukemic cells by monocyte-derived dendritic cells but interferes with subsequent cytokine-induced maturation

por van den Ancker, Willemijn, van Luijn, Marvin M., Ruben, Jurjen M., Westers, Theresia M., Bontkes, Hetty J., Ossenkoppele, Gert J., de Gruijl, Tanja D., van de Loosdrecht, Arjan A.
Publicado 2010

Phenotypic and functional characterization of T cells in white matter lesions of multiple sclerosis patients

por van Nierop, Gijsbert P., van Luijn, Marvin M., Michels, Samira S., Melief, Marie-Jose, Janssen, Malou, Langerak, Anton W., Ouwendijk, Werner J. D., Hintzen, Rogier Q., Verjans, Georges M. G. M.
Publicado 2017

Alternative Ii-independent antigen-processing pathway in leukemic blasts involves TAP-dependent peptide loading of HLA class II complexes

por van Luijn, Marvin M., Chamuleau, Martine E. D., Ressing, Maaike E., Wiertz, Emmanuel J., Ostrand-Rosenberg, Suzanne, Souwer, Yuri, Zevenbergen, Adri, Ossenkoppele, Gert J., van de Loosdrecht, Arjan A., van Ham, S. Marieke
Publicado 2010

Distinct Effector Programs of Brain-Homing CD8(+) T Cells in Multiple Sclerosis

por Koetzier, Steven C., van Langelaar, Jamie, Melief, Marie-José, Wierenga-Wolf, Annet F., Corsten, Cato E. A., Blok, Katelijn M., Hoeks, Cindy, Broux, Bieke, Wokke, Beatrijs, van Luijn, Marvin M., Smolders, Joost
Publicado 2022

Naive B cells in neuromyelitis optica spectrum disorders: impact of steroid use and relapses

por Janssen, Malou, Bruijstens, Arlette L, van Langelaar, Jamie, Wong, YuYi, Wierenga-Wolf, Annet F, Melief, Marie-José, Rijvers, Liza, van Pelt, E Daniëlle, Smolders, Joost, Wokke, Beatrijs H, van Luijn, Marvin M
Publicado 2020

Pregnancy-induced effects on memory B-cell development in multiple sclerosis

por Janssen, Malou, Rijvers, Liza, Koetzier, Steven C., Wierenga-Wolf, Annet F., Melief, Marie-José, van Langelaar, Jamie, Runia, Tessel F., de Groot, Christianne J. M., Neuteboom, Rinze, Smolders, Joost, van Luijn, Marvin M.
Publicado 2021

The association of Epstein‐Barr virus infection with CXCR3(+) B‐cell development in multiple sclerosis: impact of immunotherapies

por van Langelaar, Jamie, Wierenga‐Wolf, Annet F., Samijn, Johnny P.A., Luijks, Caroline J.M., Siepman, Theodora A., van Doorn, Pieter A., Bell, Andrew, van Zelm, Menno C., Smolders, Joost, van Luijn, Marvin M.
Publicado 2020

Promiscuous Binding of Invariant Chain-Derived CLIP Peptide to Distinct HLA-I Molecules Revealed in Leukemic Cells

por van Luijn, Marvin M., van de Loosdrecht, Arjan A., Lampen, Margit H., van Veelen, Peter A., Zevenbergen, Adri, Kester, Michel G. D., de Ru, Arnoud H., Ossenkoppele, Gert J., van Hall, Thorbald, van Ham, S. Marieke
Publicado 2012

Induction of brain‐infiltrating T‐bet–expressing B cells in multiple sclerosis

por van Langelaar, Jamie, Rijvers, Liza, Janssen, Malou, Wierenga‐Wolf, Annet F., Melief, Marie‐José, Siepman, Theodora A., de Vries, Helga E., Unger, Peter‐Paul A., van Ham, S. Marieke, Hintzen, Rogier Q., van Luijn, Marvin M.
Publicado 2019

Selective emergence of antibody-secreting cells in the multiple sclerosis brain

por Bogers, Laurens, Engelenburg, Hendrik J., Janssen, Malou, Unger, Peter-Paul A., Melief, Marie-José, Wierenga-Wolf, Annet F., Hsiao, Cheng-Chih, Mason, Matthew R.J., Hamann, Jörg, van Langelaar, Jamie, Smolders, Joost, van Luijn, Marvin M.
Publicado 2023

T cell composition and polygenic multiple sclerosis risk: A population‐based study in children

por de Mol, Casper L., Looman, Kirsten I. M., van Luijn, Marvin M., Kreft, Karim L., Jansen, Philip R., van Zelm, Menno C., Smolders, Joost J. F. M., White, Tonya J. H., Moll, Henriette A., Neuteboom, Rinze F.
Publicado 2021

The macrophage migration inhibitory factor pathway in human B cells is tightly controlled and dysregulated in multiple sclerosis

por Rijvers, Liza, Melief, Marie‐José, van der Vuurst de Vries, Roos M., Stéphant, Maeva, van Langelaar, Jamie, Wierenga‐Wolf, Annet F., Hogervorst, Jeanet M., Geurts‐Moespot, Anneke J., Sweep, Fred C. G. J., Hintzen, Rogier Q., van Luijn, Marvin M.
Publicado 2018

Effector T Helper Cells Are Selectively Controlled During Pregnancy and Related to a Postpartum Relapse in Multiple Sclerosis

por Koetzier, Steven C., Neuteboom, Rinze F., Wierenga-Wolf, Annet F., Melief, Marie-José, de Mol, C. Louk, van Rijswijk, Angelique, Dik, Willem A., Broux, Bieke, van der Wal, Ronald, van den Berg, Sjoerd A. A., Smolders, Joost, van Luijn, Marvin M.
Publicado 2021

Human T-bet(+) B cell development is associated with BTK activity and suppressed by evobrutinib

por Rijvers, Liza, van Langelaar, Jamie, Bogers, Laurens, Melief, Marie-José, Koetzier, Steven C., Blok, Katelijn M., Wierenga-Wolf, Annet F., de Vries, Helga E., Rip, Jasper, Corneth, Odilia B.J., Hendriks, Rudi W., Grenningloh, Roland, Boschert, Ursula, Smolders, Joost, van Luijn, Marvin M.
Publicado 2022

Brain-homing CD4(+) T cells display glucocorticoid-resistant features in MS

por Koetzier, Steven C., van Langelaar, Jamie, Blok, Katelijn M., van den Bosch, Thierry P.P., Wierenga-Wolf, Annet F., Melief, Marie-José, Pol, Kim, Siepman, Theodora A., Verjans, Georges M.G.M., Smolders, Joost, Lubberts, Erik, de Vries, Helga E., van Luijn, Marvin M.
Publicado 2020