Post-Translational Modifications of FXR; Implications for Cholestasis and Obesity-Related Disorders

por Appelman, Monique D., van der Veen, Suzanne W., van Mil, Saskia W. C.
Publicado 2021

Quantitative liver proteomics identifies FGF19 targets that couple metabolism and proliferation

por Massafra, Vittoria, Milona, Alexandra, Vos, Harmjan R., Burgering, Boudewijn M. T., van Mil, Saskia W. C.
Publicado 2017

High-Level MYCN-Amplified RB1-Proficient Retinoblastoma Tumors Retain Distinct Molecular Signatures

por Roohollahi, Khashayar, de Jong, Yvonne, van Mil, Saskia E., Fabius, Armida W.M., Moll, Annette C., Dorsman, Josephine C.
Publicado 2022

Identification of FDA-approved drugs targeting the Farnesoid X Receptor

por van de Wiel, Sandra M. W., Bijsmans, Ingrid T. G. W., van Mil, Saskia W. C., van de Graaf, Stan F. J.
Publicado 2019

MetaboShiny: interactive analysis and metabolite annotation of mass spectrometry-based metabolomics data

por Wolthuis, Joanna C., Magnusdottir, Stefania, Pras-Raves, Mia, Moshiri, Maryam, Jans, Judith J. M., Burgering, Boudewijn, van Mil, Saskia, de Ridder, Jeroen
Publicado 2020

Gut Microbial Diversity Is Reduced in Smokers with Crohn's Disease

por Opstelten, Jorrit L., Plassais, Jonathan, van Mil, Saskia W. C., Achouri, Emna, Pichaud, Matthieu, Siersema, Peter D., Oldenburg, Bas, Cervino, Alessandra C. L.
Publicado 2016

Farnesoid X receptor and bile acids regulate vitamin A storage

por Saeed, Ali, Yang, Jing, Heegsma, Janette, Groen, Albert K., van Mil, Saskia W. C., Paulusma, Coen C., Zhou, Lu, Wang, Bangmao, Faber, Klaas Nico
Publicado 2019

Pharmacological Activation of the Bile Acid Nuclear Farnesoid X Receptor Is Feasible in Patients with Quiescent Crohn's Colitis

por van Schaik, Fiona D. M., Gadaleta, Raffaella M., Schaap, Frank G., van Mil, Saskia W. C., Siersema, Peter D., Oldenburg, Bas, van Erpecum, Karel J.
Publicado 2012

The glucocorticoid mometasone furoate is a novel FXR ligand that decreases inflammatory but not metabolic gene expression

por Bijsmans, Ingrid T. G. W., Guercini, Chiara, Ramos Pittol, José M., Omta, Wienand, Milona, Alexandra, Lelieveld, Daphne, Egan, David A., Pellicciari, Roberto, Gioiello, Antimo, van Mil, Saskia W. C.
Publicado 2015

Multi-country metabolic signature discovery for chicken health classification

por Wolthuis, Joanna C., Magnúsdóttir, Stefanía, Stigter, Edwin, Tang, Yuen Fung, Jans, Judith, Gilbert, Myrthe, van der Hee, Bart, Langhout, Pim, Gerrits, Walter, Kies, Arie, de Ridder, Jeroen, van Mil, Saskia
Publicado 2023

Effective CRISPR/Cas9-mediated correction of a Fanconi anemia defect by error-prone end joining or templated repair

por van de Vrugt, Henri J., Harmsen, Tim, Riepsaame, Joey, Alexantya, Georgina, van Mil, Saskia E., de Vries, Yne, Bin Ali, Rahmen, Huijbers, Ivo J., Dorsman, Josephine C., Wolthuis, Rob M. F., te Riele, Hein
Publicado 2019

Loss of photoreceptorness and gain of genomic alterations in retinoblastoma reveal tumor progression

por Kooi, Irsan E., Mol, Berber M., Moll, Annette C., van der Valk, Paul, de Jong, Marcus C., de Graaf, Pim, van Mil, Saskia E., Schouten-van Meeteren, Antoinette Y.N., Meijers-Heijboer, Hanne, Kaspers, Gertjan L., te Riele, Hein, Cloos, Jacqueline, Dorsman, Josephine C.
Publicado 2015

Somatic genomic alterations in retinoblastoma beyond RB1 are rare and limited to copy number changes

por Kooi, Irsan E., Mol, Berber M., Massink, Maarten P. G., Ameziane, Najim, Meijers-Heijboer, Hanne, Dommering, Charlotte J., van Mil, Saskia E., de Vries, Yne, van der Hout, Annemarie H., Kaspers, Gertjan J. L., Moll, Annette C., te Riele, Hein, Cloos, Jacqueline, Dorsman, Josephine C.
Publicado 2016

Ablation of liver Fxr results in an increased colonic mucus barrier in mice

por Ijssennagger, Noortje, van Rooijen, Kristel S., Magnúsdóttir, Stefanía, Ramos Pittol, José M., Willemsen, Ellen C.L., de Zoete, Marcel R., Baars, Matthijs J.D., Stege, Paul B., Colliva, Carolina, Pellicciari, Roberto, Youssef, Sameh A., de Bruin, Alain, Vercoulen, Yvonne, Kuipers, Folkert, van Mil, Saskia W.C.
Publicado 2021

Steroidogenic control of liver metabolism through a nuclear receptor-network

por Milona, Alexandra, Massafra, Vittoria, Vos, Harmjan, Naik, Jyoti, Artigas, Natalia, Paterson, Helen A.B., Bijsmans, Ingrid T.G.W., Willemsen, Ellen C.L., Ramos Pittol, Jose M., Miguel-Aliaga, Irene, Bosma, Piter, Burgering, Boudewijn M.T., Williamson, Catherine, Vernia, Santiago, Dhillo, Waljit S., van Mil, Saskia W.C., Owen, Bryn M.
Publicado 2019

Farnesoid X Receptor (FXR) Activation and FXR Genetic Variation in Inflammatory Bowel Disease

por Nijmeijer, Rian M., Gadaleta, Raffaella M., van Mil, Saskia W. C., van Bodegraven, Adriaan A., Crusius, J. Bart A., Dijkstra, Gerard, Hommes, Daan W., de Jong, Dirk J., Stokkers, Pieter C. F., Verspaget, Hein W., Weersma, Rinse K., van der Woude, C. Janneke, Stapelbroek, Janneke M., Schipper, Marguerite E. I., Wijmenga, Cisca, van Erpecum, Karel J., Oldenburg, Bas
Publicado 2011

Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells

por Glykofridis, Iris E, Knol, Jaco C, Balk, Jesper A, Westland, Denise, Pham, Thang V, Piersma, Sander R, Lougheed, Sinéad M, Derakhshan, Sepide, Veen, Puck, Rooimans, Martin A, van Mil, Saskia E, Böttger, Franziska, Poddighe, Pino J, van de Beek, Irma, Drost, Jarno, Zwartkruis, Fried JT, de Menezes, Renee X, Meijers-Heijboer, Hanne EJ, Houweling, Arjan C, Jimenez, Connie R, Wolthuis, Rob MF
Publicado 2021

PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activation

por Madsen, Maria Stahl, Broekema, Marjoleine F., Madsen, Martin Rønn, Koppen, Arjen, Borgman, Anouska, Gräwe, Cathrin, Thomsen, Elisabeth G. K., Westland, Denise, Kranendonk, Mariette E. G., Koerkamp, Marian Groot, Hamers, Nicole, Bonvin, Alexandre M. J. J., Pittol, José M. Ramos, Natarajan, Kedar Nath, Kersten, Sander, Holstege, Frank C. P., Monajemi, Houshang, van Mil, Saskia W. C., Vermeulen, Michiel, Kragelund, Birthe B., Cassiman, David, Mandrup, Susanne, Kalkhoven, Eric
Publicado 2022