Models of Self-Peptide Sampling by Developing T Cells Identify Candidate Mechanisms of Thymic Selection

por Bains, Iren, van Santen, Hisse M., Seddon, Benedict, Yates, Andrew J.
Publicado 2013

Receptor Pre-Clustering and T cell Responses: Insights into Molecular Mechanisms

por Castro, Mario, van Santen, Hisse M., Férez, María, Alarcón, Balbino, Lythe, Grant, Molina-París, Carmen
Publicado 2014

Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response

por Schamel, Wolfgang W.A., Arechaga, Ignacio, Risueño, Ruth M., van Santen, Hisse M., Cabezas, Pilar, Risco, Cristina, Valpuesta, José M., Alarcón, Balbino
Publicado 2005

Modulating T Cell Responses by Targeting CD3

por Menon, Ashwathi Puravankara, Moreno, Beatriz, Meraviglia-Crivelli, Daniel, Nonatelli, Francesca, Villanueva, Helena, Barainka, Martin, Zheleva, Angelina, van Santen, Hisse M., Pastor, Fernando
Publicado 2023

RRAS2 shapes the TCR repertoire by setting the threshold for negative selection

por Martínez-Riaño, Ana, Bovolenta, Elena R., Boccasavia, Viola L., Ponomarenko, Julia, Abia, David, Oeste, Clara L., Fresno, Manuel, van Santen, Hisse M., Alarcon, Balbino
Publicado 2019

A set point in the selection of the αβTCR T cell repertoire imposed by pre-TCR signaling strength

por Bovolenta, Elena R., García-Cuesta, Eva M., Horndler, Lydia, Ponomarenko, Julia, Schamel, Wolfgang W., Mellado, Mario, Castro, Mario, Abia, David, van Santen, Hisse M.
Publicado 2022

Flow cytometry multiplexed method for the detection of neutralizing human antibodies to the native SARS‐CoV‐2 spike protein

por Horndler, Lydia, Delgado, Pilar, Abia, David, Balabanov, Ivaylo, Martínez‐Fleta, Pedro, Cornish, Georgina, Llamas, Miguel A, Serrano‐Villar, Sergio, Sánchez‐Madrid, Francisco, Fresno, Manuel, van Santen, Hisse M, Alarcón, Balbino
Publicado 2021

Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen

por Boccasavia, Viola L., Bovolenta, Elena R., Villanueva, Ana, Borroto, Aldo, Oeste, Clara L., van Santen, Hisse M., Prieto, Cristina, Alonso-López, Diego, Diaz-Muñoz, Manuel D., Batista, Facundo D., Alarcón, Balbino
Publicado 2021

ACE2 Serum Levels as Predictor of Infectability and Outcome in COVID-19

por Maza, María del Carmen, Úbeda, María, Delgado, Pilar, Horndler, Lydia, Llamas, Miguel A., van Santen, Hisse M., Alarcón, Balbino, Abia, David, García-Bermejo, Laura, Serrano-Villar, Sergio, Bastolla, Ugo, Fresno, Manuel
Publicado 2022

Decreased breadth of the antibody response to the spike protein of SARS-CoV-2 after repeated vaccination

por Horndler, Lydia, Delgado, Pilar, Romero-Pinedo, Salvador, Quesada, Marina, Balabanov, Ivaylo, Laguna-Goya, Rocío, Almendro-Vázquez, Patricia, Llamas, Miguel A., Fresno, Manuel, Paz-Artal, Estela, van Santen, Hisse M., Álvarez-Fernández, Stela, Olmo, Asunción, Alarcón, Balbino
Publicado 2023

CCR5 deficiency impairs CD4(+) T‐cell memory responses and antigenic sensitivity through increased ceramide synthesis

por Martín‐Leal, Ana, Blanco, Raquel, Casas, Josefina, Sáez, María E, Rodríguez‐Bovolenta, Elena, de Rojas, Itziar, Drechsler, Carina, Real, Luis Miguel, Fabrias, Gemma, Ruíz, Agustín, Castro, Mario, Schamel, Wolfgang WA, Alarcón, Balbino, van Santen, Hisse M, Mañes, Santos
Publicado 2020