Clinical Application of Pharmacogenetics: Where are We Now?

por van Schaik, Ron HN
Publicado 2014

6. Dose Adjustments Based on Pharmacogenetics of CYP450 Enzymes

por van Schaik, Ron H.N.
Publicado 2008

Time of injury affects urinary biomarker predictive values for acute kidney injury in critically ill, non-septic patients

por de Geus, Hilde RH, Fortrie, Gijs, Betjes, Michiel GH, van Schaik, Ron HN, Groeneveld, AB Johan
Publicado 2013

Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside?

por Mura, Elisa, Govoni, Stefano, Racchi, Marco, Carossa, Valeria, Ranzani, Guglielmina Nadia, Allegri, Massimo, van Schaik, Ron HN
Publicado 2013

CYP2D6 genotype can help to predict effectiveness and safety during opioid treatment for chronic low back pain: results from a retrospective study in an Italian cohort

por Dagostino, Concetta, Allegri, Massimo, Napolioni, Valerio, D’Agnelli, Simona, Bignami, Elena, Mutti, Antonio, van Schaik, Ron HN
Publicado 2018

Genetic Variation in the Multidrug and Toxin Extrusion 1 Transporter Protein Influences the Glucose-Lowering Effect of Metformin in Patients With Diabetes: A Preliminary Study

por Becker, Matthijs L., Visser, Loes E., van Schaik, Ron H.N., Hofman, Albert, Uitterlinden, André G., Stricker, Bruno H.Ch.
Publicado 2009

Differences in CYP3A genotypes of a liver transplant recipient and the donor liver graft and adjustment of tacrolimus dose

por Berger, Florine A., Mulder, Midas B., ten Bosch‐Dijksman, Willemijn, van Schaik, Ron H.N., Coenen, Sandra, de Winter, Brenda C.M.
Publicado 2019

Hot flashes are not predictive for serum concentrations of tamoxifen and its metabolites

por Jager, Nynke GL, Koornstra, Rutger HT, Vincent, Andrew D, van Schaik, Ron HN, Huitema, Alwin DR, Korse, Tiny M, Schellens, Jan HM, Linn, Sabine C, Beijnen, Jos H
Publicado 2013

Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Starting Dose

por Andrews, Louise M., de Winter, Brenda C.M., Tang, Jiang-Tao, Shuker, Nauras, Bouamar, Rachida, van Schaik, Ron H.N., Koch, Birgit C.P., van Gelder, Teun, Hesselink, Dennis A.
Publicado 2017

Cardiac Toxicity of Alectinib in Patients With ALK+ Lung Cancer: Outcomes of Cardio-Oncology Follow-Up

por Pruis, Melinda A., Veerman, G.D. Marijn, Hassing, H. Carlijne, Lanser, Daan A.C., Paats, Marthe S., van Schaik, Ron H.N., Mathijssen, Ron H.J., Manintveld, Olivier, Dingemans, Anne-Marie C.
Publicado 2023

Monitoring the tacrolimus concentration in peripheral blood mononuclear cells of kidney transplant recipients

por Francke, Marith I., Hesselink, Dennis A., Li, Yi, Koch, Birgit C.P., de Wit, Lucia E.A., van Schaik, Ron H.N., Yang, Lin, Baan, Carla C., van Gelder, Teun, de Winter, Brenda C.M.
Publicado 2020

Influence of Genetic Variation in COMT on Cisplatin-Induced Nephrotoxicity in Cancer Patients

por Agema, Bram C., Koolen, Stijn L.W., de With, Mirjam, van Doorn, Nadia, Heersche, Niels, Oomen-de Hoop, Esther, Visser, Sabine, Aerts, Joachim G.J.V., Bins, Sander, van Schaik, Ron H.N., Mathijssen, Ron H.J.
Publicado 2020

Patients with NSCLC may display a low ratio of p.T790M vs. activating EGFR mutations in plasma at disease progression: implications for personalised treatment

por Del Re, Marzia, Bordi, Paola, Petrini, Iacopo, Rofi, Eleonora, Mazzoni, Francesca, Belluomini, Lorenzo, Vasile, Enrico, Restante, Giuliana, Di Costanzo, Francesco, Falcone, Alfredo, Frassoldati, Antonio, van Schaik, Ron H.N., Steendam, Christi M.J., Chella, Antonio, Tiseo, Marcello, Morganti, Riccardo, Danesi, Romano
Publicado 2017

Impact of Curcumin (with or without Piperine) on the Pharmacokinetics of Tamoxifen

por Hussaarts, Koen G.A.M., Hurkmans, Daan P., Oomen-de Hoop, Esther, van Harten, Leonie J., Berghuis, Stan, van Alphen, Robbert J., Spierings, Leontine E.A., van Rossum-Schornagel, Quirine C., Vastbinder, Mijntje B., van Schaik, Ron H.N., van Gelder, Teun, Jager, Agnes, van Leeuwen, Roelof W.F., Mathijssen, Ron H.J.
Publicado 2019

Influence of germline variations in drug transporters ABCB1 and ABCG2 on intracerebral osimertinib efficacy in patients with non-small cell lung cancer

por Veerman, G.D. Marijn, Boosman, Rene J., Jebbink, Merel, Oomen-de Hoop, Esther, van der Wekken, Anthonie J., Bahce, Idris, Hendriks, Lizza E.L., Croes, Sander, Steendam, Christi M.J., de Jonge, Evert, Koolen, Stijn L.W., Steeghs, Neeltje, van Schaik, Ron H.N., Smit, Egbert F., Dingemans, Anne-Marie C., Huitema, Alwin D.R., Mathijssen, Ron H.J.
Publicado 2023

Risperidone plasma concentrations are associated with side effects and effectiveness in children and adolescents with autism spectrum disorder

por Kloosterboer, Sanne Maartje, de Winter, Brenda C.M., Reichart, Catrien G., Kouijzer, Mirjam E.J., de Kroon, Matthias M.J., van Daalen, Emma, Ester, Wietske A., Rieken, Rob, Dieleman, Gwen C., van Altena, Daphne, Bartelds, Beatrijs, van Schaik, Ron H.N., Nasserinejad, Kazem, Hillegers, Manon H.J., van Gelder, Teun, Dierckx, Bram, Koch, Birgit C.P.
Publicado 2020

A low aldosterone/renin ratio and high soluble ACE2 associate with COVID-19 severity

por Akin, Sakir, Schriek, Paula, van Nieuwkoop, Cees, Neuman, Rugina I., Meynaar, Iwan, van Helden, Erik J., Bouazzaoui, Hassan El, Baak, Remon, Veuger, Marjan, Mairuhu, Ronne A.T.A., van den Berg, Lettie, van Driel, Vincent, Visser, Loes E., de Jonge, Evert, Garrelds, Ingrid M., Duynstee, Johannes F.A.B., van Rooden, Jan Kees, Ludikhuize, Jeroen, Verdonk, Koen, Caliskan, Kadir, Jansen, Tim, van Schaik, Ron H.N., Danser, A.H. Jan
Publicado 2022

Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

por Conti, David V., Darst, Burcu F., Moss, Lilit C., Saunders, Edward J., Sheng, Xin, Chou, Alisha, Schumacher, Fredrick R., Olama, Ali Amin Al, Benlloch, Sara, Dadaev, Tokhir, Brook, Mark N., Sahimi, Ali, Hoffmann, Thomas J., Takahashi, Atushi, Matsuda, Koichi, Momozawa, Yukihide, Fujita, Masashi, Muir, Kenneth, Lophatananon, Artitaya, Wan, Peggy, Marchand, Loic Le, Wilkens, Lynne R., Stevens, Victoria L., Gapstur, Susan M., Carter, Brian D., Schleutker, Johanna, Tammela, Teuvo L. J., Sipeky, Csilla, Auvinen, Anssi, Giles, Graham G., Southey, Melissa C., MacInnis, Robert J., Cybulski, Cezary, Wokołorczyk, Dominika, Lubiński, Jan, Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Martin, Richard M., Nordestgaard, Børge G., Nielsen, Sune F., Weischer, Maren, Bojesen, Stig E., Røder, Martin Andreas, Iversen, Peter, Batra, Jyohtsna, Chambers, Suzanne, Moya, Leire, Horvath, Lisa, Clements, Judith A., Tilley, Wayne, Risbridger, Gail P., Gronberg, Henrik, Aly, Markus, Szulkin, Robert, Eklund, Martin, Nordström, Tobias, Pashayan, Nora, Dunning, Alison M., Ghoussaini, Maya, Travis, Ruth C., Key, Tim J., Riboli, Elio, Park, Jong Y., Sellers, Thomas A., Lin, Hui-Yi, Albanes, Demetrius, Weinstein, Stephanie J., Mucci, Lorelei A., Giovannucci, Edward, Lindstrom, Sara, Kraft, Peter, Hunter, David J., Penney, Kathryn L., Turman, Constance, Tangen, Catherine M., Goodman, Phyllis J., Thompson, Ian M., Hamilton, Robert J., Fleshner, Neil E., Finelli, Antonio, Parent, Marie-Élise, Stanford, Janet L., Ostrander, Elaine A., Geybels, Milan S., Koutros, Stella, Freeman, Laura E. Beane, Stampfer, Meir, Wolk, Alicja, Håkansson, Niclas, Andriole, Gerald L., Hoover, Robert N., Machiela, Mitchell J., Sørensen, Karina Dalsgaard, Borre, Michael, Blot, William J., Zheng, Wei, Yeboah, Edward D., Mensah, James E., Lu, Yong-Jie, Zhang, Hong-Wei, Feng, Ninghan, Mao, Xueying, Wu, Yudong, Zhao, Shan-Chao, Sun, Zan, Thibodeau, Stephen N., McDonnell, Shannon K., Schaid, Daniel J., West, Catharine M. L., Burnet, Neil, Barnett, Gill, Maier, Christiane, Schnoeller, Thomas, Luedeke, Manuel, Kibel, Adam S., Drake, Bettina F., Cussenot, Olivier, Cancel-Tassin, Géraldine, Menegaux, Florence, Truong, Thérèse, Koudou, Yves Akoli, John, Esther M., Grindedal, Eli Marie, Maehle, Lovise, Khaw, Kay-Tee, Ingles, Sue A., Stern, Mariana C., Vega, Ana, Gómez-Caamaño, Antonio, Fachal, Laura, Rosenstein, Barry S., Kerns, Sarah L., Ostrer, Harry, Teixeira, Manuel R., Paulo, Paula, Brandão, Andreia, Watya, Stephen, Lubwama, Alexander, Bensen, Jeannette T., Fontham, Elizabeth T.H., Mohler, James, Taylor, Jack A., Kogevinas, Manolis, Llorca, Javier, Castaño-Vinyals, Gemma, Cannon-Albright, Lisa, Teerlink, Craig C., Huff, Chad D., Strom, Sara S., Multigner, Luc, Blanchet, Pascal, Brureau, Laurent, Kaneva, Radka, Slavov, Chavdar, Mitev, Vanio, Leach, Robin J., Weaver, Brandi, Brenner, Hermann, Cuk, Katarina, Holleczek, Bernd, Saum, Kai-Uwe, Klein, Eric A., Hsing, Ann W., Kittles, Rick A., Murphy, Adam B., Logothetis, Christopher J., Kim, Jeri, Neuhausen, Susan L., Steele, Linda, Chun Ding, Yuan, Isaacs, William B., Nemesure, Barbara, Hennis, Anselm J. M., Carpten, John, Pandha, Hardev, Michael, Agnieszka, De Ruyck, Kim, De Meerleer, Gert, Ost, Piet, Xu, Jianfeng, Razack, Azad, Lim, Jasmine, Teo, Soo-Hwang, Newcomb, Lisa F., Lin, Daniel W., Fowke, Jay H., Neslund-Dudas, Christine, Rybicki, Benjamin A., Gamulin, Marija, Lessel, Davor, Kulis, Tomislav, Usmani, Nawaid, Singhal, Sandeep, Parliament, Matthew, Claessens, Frank, Joniau, Steven, Van den Broeck, Thomas, Gago-Dominguez, Manuela, Esteban Castelao, Jose, Martinez, Maria Elena, Larkin, Samantha, Townsend, Paul A., Aukim-Hastie, Claire, Bush, William S., Aldrich, Melinda C., Crawford, Dana C., Srivastava, Shiv, Cullen, Jennifer C., Petrovics, Gyorgy, Casey, Graham, Roobol, Monique J., Jenster, Guido, van Schaik, Ron H.N., Hu, Jennifer J., Sanderson, Maureen, Varma, Rohit, McKean-Cowdin, Roberta, Torres, Mina, Mancuso, Nicholas, Berndt, Sonja I., Van Den Eeden, Stephen K., Easton, Douglas F, Chanock, Stephen J., Cook, Michael B., Wiklund, Fredrik, Nakagawa, Hidewaki, Witte, John S., Eeles, Rosalind A., Kote-Jarai, Zsofia, Haiman, Christopher A.
Publicado 2021