CD95 ligand induces senescence in mismatch repair-deficient human colon cancer via chronic caspase-mediated induction of DNA damage

por Raats, Danielle A, Frenkel, Nicola, van Schelven, Susanne J, Rinkes, Inne HMBorel, Laoukili, Jamila, Kranenburg, Onno
Publicado 2017

Mismatch Repair Status in Patient-Derived Colorectal Cancer Organoids Does Not Affect Intrinsic Tumor Cell Sensitivity to Systemic Therapy

por Küçükköse, Emre, Wensink, G. Emerens, Roelse, Celine M., van Schelven, Susanne J., Raats, Daniëlle A. E., Boj, Sylvia F., Koopman, Miriam, Laoukili, Jamila, Roodhart, Jeanine M. L., Kranenburg, Onno
Publicado 2021

Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability

por Jongen, Jennifer M. J., van der Waals, Lizet M., Trumpi, Kari, Laoukili, Jamila, Peters, Niek A., Schenning-van Schelven, Susanne J., Govaert, Klaas M., Borel Rinkes, Inne H. M., Kranenburg, Onno
Publicado 2017

Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity

por Laoukili, Jamila, Constantinides, Alexander, Wassenaar, Emma C. E., Elias, Sjoerd G., Raats, Danielle A. E., van Schelven, Susanne J., van Wettum, Jonathan, Volckmann, Richard, Koster, Jan, Huitema, Alwin D. R., Nienhuijs, Simon W., de Hingh, Ignace H. J. T., Wiezer, René J., van Grevenstein, Helma M. U., Rinkes, Inne H. M. Borel, Boerma, Djamila, Kranenburg, Onno
Publicado 2022