HIV-1 immunogens and strategies to drive antibody responses towards neutralization breadth

por van Schooten, Jelle, van Gils, Marit J.
Publicado 2018

Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity

por Liu, Hejun, Wu, Nicholas C., Yuan, Meng, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., van Schooten, Jelle, Zhu, Xueyong, Lee, Chang-Chun D., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
Publicado 2020

Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity

por Liu, Hejun, Wu, Nicholas C., Yuan, Meng, Bangaru, Sandhya, Torres, Jonathan L., Caniels, Tom G., van Schooten, Jelle, Zhu, Xueyong, Lee, Chang-Chun D., Brouwer, Philip J.M., van Gils, Marit J., Sanders, Rogier W., Ward, Andrew B., Wilson, Ian A.
Publicado 2020

Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates

por van Schooten, Jelle, van Haaren, Marlies M., Li, Hui, McCoy, Laura E., Havenar-Daughton, Colin, Cottrell, Christopher A., Burger, Judith A., van der Woude, Patricia, Helgers, Leanne C., Tomris, Ilhan, Labranche, Celia C., Montefiori, David C., Ward, Andrew B., Burton, Dennis R., Moore, John P., Sanders, Rogier W., Crotty, Shane, Shaw, George M., van Gils, Marit J.
Publicado 2021

Fusion peptide priming reduces immune responses to HIV-1 envelope trimer base

por Corrigan, Angela R., Duan, Hongying, Cheng, Cheng, Gonelli, Christopher A., Ou, Li, Xu, Kai, DeMouth, Megan E., Geng, Hui, Narpala, Sandeep, O’Connell, Sarah, Zhang, Baoshan, Zhou, Tongqing, Basappa, Manjula, Boyington, Jeffrey C., Chen, Steven J., O’Dell, Sijy, Pegu, Amarendra, Stephens, Tyler, Tsybovsky, Yaroslav, van Schooten, Jelle, Todd, John P., Wang, Shuishu, Doria-Rose, Nicole A., Foulds, Kathryn E., Koup, Richard A., McDermott, Adrian B., van Gils, Marit J., Kwong, Peter D., Mascola, John R.
Publicado 2021

The Glycan Hole Area of HIV-1 Envelope Trimers Contributes Prominently to the Induction of Autologous Neutralization

por Schorcht, Anna, Cottrell, Christopher A., Pugach, Pavel, Ringe, Rajesh P., Han, Alvin X., Allen, Joel D., van den Kerkhof, Tom L. G. M., Seabright, Gemma E., Schermer, Edith E., Ketas, Thomas J., Burger, Judith A., van Schooten, Jelle, LaBranche, Celia C., Ozorowski, Gabriel, de Val, Natalia, Bader, Daniel L. V., Schuitemaker, Hanneke, Russell, Colin A., Montefiori, David C., van Gils, Marit J., Crispin, Max, Klasse, P. J., Ward, Andrew B., Moore, John P., Sanders, Rogier W.
Publicado 2022

Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein

por van Schooten, Jelle, Farokhi, Elinaz, Schorcht, Anna, van den Kerkhof, Tom L. G. M., Gao, Hongmei, van der Woude, Patricia, Burger, Judith A., Meesters, Tim G. Rijkhold, Bijl, Tom, Ghalaiyini, Riham, Turner, Hannah L., Dorning, Jessica, van Schaik, Barbera D. C., van Kampen, Antoine H. C., Labranche, Celia C., Stanfield, Robyn L., Sok, Devin, Montefiori, David C., Burton, Dennis R., Seaman, Michael S., Ozorowski, Gabriel, Wilson, Ian A., Sanders, Rogier W., Ward, Andrew B., van Gils, Marit J.
Publicado 2022

Complementary antibody lineages achieve neutralization breadth in an HIV-1 infected elite neutralizer

por van Schooten, Jelle, Schorcht, Anna, Farokhi, Elinaz, Umotoy, Jeffrey C., Gao, Hongmei, van den Kerkhof, Tom L. G. M., Dorning, Jessica, Rijkhold Meesters, Tim G., van der Woude, Patricia, Burger, Judith A., Bijl, Tom, Ghalaiyini, Riham, Torrents de la Peña, Alba, Turner, Hannah L., Labranche, Celia C., Stanfield, Robyn L., Sok, Devin, Schuitemaker, Hanneke, Montefiori, David C., Burton, Dennis R., Ozorowski, Gabriel, Seaman, Michael S., Wilson, Ian A., Sanders, Rogier W., Ward, Andrew B., van Gils, Marit J.
Publicado 2022

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

por Cottrell, Christopher A., van Schooten, Jelle, Bowman, Charles A., Yuan, Meng, Oyen, David, Shin, Mia, Morpurgo, Robert, van der Woude, Patricia, van Breemen, Mariëlle, Torres, Jonathan L., Patel, Raj, Gross, Justin, Sewall, Leigh M., Copps, Jeffrey, Ozorowski, Gabriel, Nogal, Bartek, Sok, Devin, Rakasz, Eva G., Labranche, Celia, Vigdorovich, Vladimir, Christley, Scott, Carnathan, Diane G., Sather, D. Noah, Montefiori, David, Silvestri, Guido, Burton, Dennis R., Moore, John P., Wilson, Ian A., Sanders, Rogier W., Ward, Andrew B., van Gils, Marit J.
Publicado 2020

Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques

por Nelson, Ashley N., Shen, Xiaoying, Vekatayogi, Sravani, Zhang, Shiyu, Ozorowski, Gabriel, Dennis, Maria, Sewall, Leigh M., Milligan, Emma, Davis, Dominique, Cross, Kaitlyn A., Chen, Yue, van Schooten, Jelle, Eudailey, Joshua, Isaac, John, Memon, Saad, Weinbaum, Carolyn, Stanfield-Oakley, Sherry, Byrd, Alliyah, Chutkan, Suni, Berendam, Stella, Cronin, Kenneth, Yasmeen, Anila, Alam, S. Munir, LaBranche, Celia C., Rogers, Kenneth, Shirreff, Lisa, Cupo, Albert, Derking, Ronald, Villinger, Francois, Klasse, Per Johan, Ferrari, Guido, Williams, Wilton B., Hudgens, Michael G., Ward, Andrew B., Montefiori, David C., Van Rompay, Koen K.A., Wiehe, Kevin, Moore, John P., Sanders, Rogier W., De Paris, Kristina, Permar, Sallie R.
Publicado 2023

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

por Brouwer, Philip J. M., Caniels, Tom G., van der Straten, Karlijn, Snitselaar, Jonne L., Aldon, Yoann, Bangaru, Sandhya, Torres, Jonathan L., Okba, Nisreen M. A., Claireaux, Mathieu, Kerster, Gius, Bentlage, Arthur E. H., van Haaren, Marlies M., Guerra, Denise, Burger, Judith A., Schermer, Edith E., Verheul, Kirsten D., van der Velde, Niels, van der Kooi, Alex, van Schooten, Jelle, van Breemen, Mariëlle J., Bijl, Tom P. L., Sliepen, Kwinten, Aartse, Aafke, Derking, Ronald, Bontjer, Ilja, Kootstra, Neeltje A., Wiersinga, W. Joost, Vidarsson, Gestur, Haagmans, Bart L., Ward, Andrew B., de Bree, Godelieve J., Sanders, Rogier W., van Gils, Marit J.
Publicado 2020

Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

por Brouwer, Philip J.M., Brinkkemper, Mitch, Maisonnasse, Pauline, Dereuddre-Bosquet, Nathalie, Grobben, Marloes, Claireaux, Mathieu, de Gast, Marlon, Marlin, Romain, Chesnais, Virginie, Diry, Ségolène, Allen, Joel D., Watanabe, Yasunori, Giezen, Julia M., Kerster, Gius, Turner, Hannah L., van der Straten, Karlijn, van der Linden, Cynthia A., Aldon, Yoann, Naninck, Thibaut, Bontjer, Ilja, Burger, Judith A., Poniman, Meliawati, Mykytyn, Anna Z., Okba, Nisreen M.A., Schermer, Edith E., van Breemen, Marielle J., Ravichandran, Rashmi, Caniels, Tom G., van Schooten, Jelle, Kahlaoui, Nidhal, Contreras, Vanessa, Lemaître, Julien, Chapon, Catherine, Fang, Raphaël Ho Tsong, Villaudy, Julien, Sliepen, Kwinten, van der Velden, Yme U., Haagmans, Bart L., de Bree, Godelieve J., Ginoux, Eric, Ward, Andrew B., Crispin, Max, King, Neil P., van der Werf, Sylvie, van Gils, Marit J., Le Grand, Roger, Sanders, Rogier W.
Publicado 2021

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

por Maisonnasse, Pauline, Aldon, Yoann, Marc, Aurélien, Marlin, Romain, Dereuddre-Bosquet, Nathalie, Kuzmina, Natalia A., Freyn, Alec W., Snitselaar, Jonne L., Gonçalves, Antonio, Caniels, Tom G., Burger, Judith A., Poniman, Meliawati, Bontjer, Ilja, Chesnais, Virginie, Diry, Ségolène, Iershov, Anton, Ronk, Adam J., Jangra, Sonia, Rathnasinghe, Raveen, Brouwer, Philip J. M., Bijl, Tom P. L., van Schooten, Jelle, Brinkkemper, Mitch, Liu, Hejun, Yuan, Meng, Mire, Chad E., van Breemen, Mariëlle J., Contreras, Vanessa, Naninck, Thibaut, Lemaître, Julien, Kahlaoui, Nidhal, Relouzat, Francis, Chapon, Catherine, Ho Tsong Fang, Raphaël, McDanal, Charlene, Osei-Twum, Mary, St-Amant, Natalie, Gagnon, Luc, Montefiori, David C., Wilson, Ian A., Ginoux, Eric, de Bree, Godelieve J., García-Sastre, Adolfo, Schotsaert, Michael, Coughlan, Lynda, Bukreyev, Alexander, van der Werf, Sylvie, Guedj, Jérémie, Sanders, Rogier W., van Gils, Marit J., Le Grand, Roger
Publicado 2021