Shutting down the power supply for DNA repair in cancer cells

por van Vugt, Marcel A.T.M.
Publicado 2017

Inflammatory signaling in genomically instable cancers

por Talens, Francien, Van Vugt, Marcel A.T.M.
Publicado 2019

Editorial: Cancer-Associated Defects in the DNA Damage Response: Drivers for Malignant Transformation and Potential Therapeutic Targets

por van Vugt, Marcel A. T. M., Reinhardt, H. Christian
Publicado 2015

Never tear us a-PARP: Dealing with DNA lesions during mitosis

por Schoonen, Pepijn M., van Vugt, Marcel A.T.M.
Publicado 2017

Controlling the response to DNA damage by the APC/C-Cdh1

por de Boer, H. Rudolf, Guerrero Llobet, S., van Vugt, Marcel A. T. M.
Publicado 2015

Erratum to: Controlling the response to DNA damage by the APC/C-Cdh1

por de Boer, H. Rudolf, Llobet, Sergi Guerrero, van Vugt, Marcel A. T. M.
Publicado 2016

Shaping the BRCAness mutational landscape by alternative double-strand break repair, replication stress and mitotic aberrancies

por Stok, Colin, Kok, Yannick P, van den Tempel, Nathalie, van Vugt, Marcel A T M
Publicado 2021

Processing DNA lesions during mitosis to prevent genomic instability

por Audrey, Anastasia, de Haan, Lauren, van Vugt, Marcel A.T.M., de Boer, H. Rudolf
Publicado 2022

Regulators of homologous recombination repair as novel targets for cancer treatment

por Krajewska, Małgorzata, Fehrmann, Rudolf S. N., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M.
Publicado 2015

Harnessing Integrative Omics to Facilitate Molecular Imaging of the Human Epidermal Growth Factor Receptor Family for Precision Medicine

por Pool, Martin, de Boer, H. Rudolf, Hooge, Marjolijn N. Lub-de, van Vugt, Marcel A.T.M., de Vries, Elisabeth G.E.
Publicado 2017

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2‐deficient cancer c...

por Schoonen, Pepijn M., Kok, Yannick P., Wierenga, Elles, Bakker, Bjorn, Foijer, Floris, Spierings, Diana C. J., van Vugt, Marcel A. T. M.
Publicado 2019

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity

por Heijink, Anne Margriet, Talens, Francien, Jae, Lucas T., van Gijn, Stephanie E., Fehrmann, Rudolf S. N., Brummelkamp, Thijn R., van Vugt, Marcel A. T. M.
Publicado 2019

Transcriptional effects of copy number alterations in a large set of human cancers

por Bhattacharya, Arkajyoti, Bense, Rico D., Urzúa-Traslaviña, Carlos G., de Vries, Elisabeth G. E., van Vugt, Marcel A. T. M., Fehrmann, Rudolf S. N.
Publicado 2020

An mRNA expression-based signature for oncogene-induced replication-stress

por Llobet, Sergi Guerrero, Bhattacharya, Arkajyoti, Everts, Marieke, Kok, Klaas, van der Vegt, Bert, Fehrmann, Rudolf S.N., van Vugt, Marcel A.T.M.
Publicado 2022

miR-371a-3p, miR-373-3p and miR-367-3p as Serum Biomarkers in Metastatic Testicular Germ Cell Cancers Before, During and After Chemotherapy

por Rosas Plaza, Ximena, van Agthoven, Ton, Meijer, Coby, van Vugt, Marcel A. T. M., de Jong, Steven, Gietema, Jourik A., Looijenga, Leendert H. J.
Publicado 2019

Improving gene function predictions using independent transcriptional components

por Urzúa-Traslaviña, Carlos G., Leeuwenburgh, Vincent C., Bhattacharya, Arkajyoti, Loipfinger, Stefan, van Vugt, Marcel A. T. M., de Vries, Elisabeth G. E., Fehrmann, Rudolf S. N.
Publicado 2021

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors

por Kok, Yannick P., Guerrero Llobet, Sergi, Schoonen, Pepijn M., Everts, Marieke, Bhattacharya, Arkajyoti, Fehrmann, Rudolf S. N., van den Tempel, Nathalie, van Vugt, Marcel A. T. M.
Publicado 2020

Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

por Heijink, Anne Margriet, Everts, Marieke, Honeywell, Megan E., Richards, Ryan, Kok, Yannick P., de Vries, Elisabeth G.E., Lee, Michael J., van Vugt, Marcel A.T.M.
Publicado 2019

Polo-Like Kinase-1 Controls Aurora A Destruction by Activating APC/C-Cdh1

por van Leuken, Renske, Clijsters, Linda, van Zon, Wouter, Lim, Dan, Yao, XueBiao, Wolthuis, Rob M. F., Yaffe, Michael B., Medema, René H., van Vugt, Marcel A. T. M.
Publicado 2009

RIF1 promotes replication fork protection and efficient restart to maintain genome stability

por Mukherjee, Chirantani, Tripathi, Vivek, Manolika, Eleni Maria, Heijink, Anne Margriet, Ricci, Giulia, Merzouk, Sarra, de Boer, H. Rudolf, Demmers, Jeroen, van Vugt, Marcel A. T. M., Ray Chaudhuri, Arnab
Publicado 2019