Finding the right hazard function for time‐to‐event modeling: A tutorial and Shiny application

por Van Wijk, Rob C., Simonsson, Ulrika S. H.
Publicado 2022

Pharmacokinetic analysis across studies to drive knowledge‐integration: A tutorial on individual patient data meta‐analysis (IPDMA)

por van Wijk, Rob C., Imperial, Marjorie Z., Savic, Radojka M., Solans, Belén P.
Publicado 2023

Seasonal influence on respiratory tract infection severity including COVID‐19 quantified through Markov Chain modeling

por van Wijk, Rob C., Mockeliunas, Laurynas, Upton, Caryn M., Peter, Jonathan, Diacon, Andreas H., Simonsson, Ulrika S. H.
Publicado 2023

Model‐informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy

por Faraj, Alan, van Wijk, Rob C., Neuman, Linda, Desai, Shraddha, Blouse, Grant E., Knudsen, Tom, Simonsson, Ulrika S. H.
Publicado 2023

Reproducibility in pharmacometrics applied in a phase III trial of BCG-vaccination for COVID-19

por van Wijk, Rob C., Mockeliunas, Laurynas, van den Hoogen, Gerben, Upton, Caryn M., Diacon, Andreas H., Simonsson, Ulrika S. H.
Publicado 2023

Standards for model-based early bactericidal activity analysis and sample size determination in tuberculosis drug development

por Mockeliunas, Laurynas, Faraj, Alan, van Wijk, Rob C., Upton, Caryn M., van den Hoogen, Gerben, Diacon, Andreas H., Simonsson, Ulrika S. H.
Publicado 2023

Outside‐In Systems Pharmacology Combines Innovative Computational Methods With High‐Throughput Whole Vertebrate Studies

por Schulthess, Pascal, van Wijk, Rob C., Krekels, Elke H. J., Yates, James W. T., Spaink, Herman P., van der Graaf, Piet H.
Publicado 2018

Impact of post-hatching maturation on the pharmacokinetics of paracetamol in zebrafish larvae

por van Wijk, Rob C., Krekels, Elke H. J., Kantae, Vasudev, Harms, Amy C., Hankemeier, Thomas, van der Graaf, Piet H., Spaink, Herman P.
Publicado 2019

Translational predictions of phase 2a first-in-patient efficacy studies for antituberculosis drugs

por Ernest, Jacqueline P., Goh, Janice Jia Ni, Strydom, Natasha, Wang, Qianwen, van Wijk, Rob C., Zhang, Nan, Deitchman, Amelia, Nuermberger, Eric, Savic, Rada M.
Publicado 2023

Quantification of Natural Growth of Two Strains of Mycobacterium Marinum for Translational Antituberculosis Drug Development

por Van Wijk, Rob C., van der Sar, Astrid M., Krekels, Elke H.J., Verboom, Theo, Spaink, Herman P., Simonsson, Ulrika S.H., van der Graaf, Piet H.
Publicado 2020

Pharmacokinetic Modeling of Paracetamol Uptake and Clearance in Zebrafish Larvae: Expanding the Allometric Scale in Vertebrates with Five Orders of Magnitude

por Kantae, Vasudev, Krekels, Elke H.J., Ordas, Anita, González, Oskar, van Wijk, Rob C., Harms, Amy C., Racz, Peter I., van der Graaf, Piet H., Spaink, Herman P., Hankemeier, Thomas
Publicado 2016

Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans

por van Wijk, Rob C., Hu, Wanbin, Dijkema, Sharka M., van den Berg, Dirk‐Jan, Liu, Jeremy, Bahi, Rida, Verbeek, Fons J., Simonsson, Ulrika S.H., Spaink, Herman P., van der Graaf, Piet H., Krekels, Elke H.J.
Publicado 2020

Safety and efficacy of BCG re-vaccination in relation to COVID-19 morbidity in healthcare workers: A double-blind, randomised, controlled, phase 3 trial

por Upton, Caryn M., van Wijk, Rob C., Mockeliunas, Laurynas, Simonsson, Ulrika S.H., McHarry, Kirsten, van den Hoogen, Gerben, Muller, Chantal, von Delft, Arné, van der Westhuizen, Helene-Mari, van Crevel, Reinout, Walzl, Gerhard, Baptista, Pedro M., Peter, Jonathan, Diacon, Andreas H.
Publicado 2022