Bile Salts by the Back Road

por Oude Elferink, Ronald P.J., Van De Graaf, Stan F.J.
Publicado 2023

Mechanistic insights into the inhibition of NTCP by myrcludex B

por Donkers, Joanne M., Appelman, Monique D., van de Graaf, Stan F.J.
Publicado 2019

Current and future therapies for inherited cholestatic liver diseases

por van der Woerd, Wendy L, Houwen, Roderick HJ, van de Graaf, Stan FJ
Publicado 2017

The Somatic FAH c.1061C>A Change Counteracts the Frequent FAH c.1062+5G>A Mutation and Permits U1snRNA-Based Splicing Correction

por Scalet, Daniela, Sacchetto, Claudia, Bernardi, Francesco, Pinotti, Mirko, van de Graaf, Stan F.J., Balestra, Dario
Publicado 2018

Targeting the Four Pillars of Enterohepatic Bile Salt Cycling; Lessons From Genetics and Pharmacology

por Kunst, Roni F., Verkade, Henkjan J., Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Publicado 2021

Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β

por van de Wiel, Sandra M.W., de Waart, D. Rudi, Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Publicado 2017

Reply

por Roscam Abbing, Reinout L.P., Kuipers, Folkert, Paulusma, Coen C., Verkade, Henkjan J., Groen, Albert K., Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Publicado 2020

ATP8B1-mediated spatial organization of Cdc42 signaling maintains singularity during enterocyte polarization

por Bruurs, Lucas J.M., Donker, Lisa, Zwakenberg, Susan, Zwartkruis, Fried J., Begthel, Harry, Knisely, A.S., Posthuma, George, van de Graaf, Stan F.J., Paulusma, Coen C., Bos, Johannes L.
Publicado 2015

Na(+)‐taurocholate cotransporting polypeptide inhibition has hepatoprotective effects in cholestasis in mice

por Slijepcevic, Davor, Roscam Abbing, Reinout L.P., Fuchs, Claudia D., Haazen, Lizette C.M., Beuers, Ulrich, Trauner, Michael, Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Publicado 2018

Inhibition of Hepatic Bile Acid Uptake by Myrcludex B Promotes Glucagon-Like Peptide-1 Release and Reduces Obesity

por Donkers, Joanne M., Roscam Abbing, Reinout L.P., van Weeghel, Michel, Levels, Johannes H.M., Boelen, Anita, Schinkel, Alfred H., Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Publicado 2020

Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice

por Kunst, Roni F., de Waart, Dirk R., Wolters, Frank, Duijst, Suzanne, Vogels, Esther W., Bolt, Isabelle, Verheij, Joanne, Beuers, Ulrich, Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Publicado 2022

Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na(+)‐Taurocholate Cotransporting Polypeptide

por Robin, Marion J.D., Appelman, Monique D., Vos, Harmjan R., van Es, Robert M., Paton, James C., Paton, Adrienne W., Burgering, Boudewijn, Fickert, Peter, Heijmans, Jarom, van de Graaf, Stan F.J.
Publicado 2018

The Lipid Raft Component Stomatin Interacts with the Na(+) Taurocholate Cotransporting Polypeptide (NTCP) and Modulates Bile Salt Uptake

por Appelman, Monique D., Robin, Marion J.D., Vogels, Esther W.M., Wolzak, Christie, Vos, Winnie G., Vos, Harmjan R., Van Es, Robert M., Burgering, Boudewijn M.T., Van de Graaf, Stan F.J.
Publicado 2020

Blocking Sodium‐Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice

por Roscam Abbing, Reinout L.P., Slijepcevic, Davor, Donkers, Joanne M., Havinga, Rick, Duijst, Suzanne, Paulusma, Coen C., Kuiper, Johan, Kuipers, Folkert, Groen, Albert K., Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Publicado 2019

Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+)-taurocholate cotransporting polypeptide knockout mice

por Slijepcevic, Davor, Kaufman, Christina, Wichers, Catharina GK, Gilglioni, Eduardo H, Lempp, Florian A, Duijst, Suzanne, de Waart, Dirk R, Oude Elferink, Ronald PJ, Mier, Walter, Stieger, Bruno, Beuers, Ulrich, Urban, Stephan, van de Graaf, Stan FJ
Publicado 2015

Differential and organ-specific functions of organic solute transporter α and β in experimental cholestasis

por van de Wiel, Sandra M.W., Porteiro, Begoña, Belt, Saskia C., Vogels, Esther W.M., Bolt, Isabelle, Vermeulen, Jacqueline L.M., de Waart, D. Rudi, Verheij, Joanne, Muncan, Vanesa, Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Publicado 2022

NTCP deficiency in mice protects against obesity and hepatosteatosis

por Donkers, Joanne M., Kooijman, Sander, Slijepcevic, Davor, Kunst, Roni F., Roscam Abbing, Reinout L.P., Haazen, Lizette, de Waart, Dirk R., Levels, Johannes H.M., Schoonjans, Kristina, Rensen, Patrick C.N., Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Publicado 2019

Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal s...

por Slijepcevic, Davor, Roscam Abbing, Reinout L.P., Katafuchi, Takeshi, Blank, Antje, Donkers, Joanne M., van Hoppe, Stéphanie, de Waart, Dirk. R., Tolenaars, Dagmar, van der Meer, Jonathan H.M., Wildenberg, Manon, Beuers, Ulrich, Oude Elferink, Ronald P.J., Schinkel, Alfred H., van de Graaf, Stan F.J.
Publicado 2017