ProteoDisco: a flexible R approach to generate customized protein databases for extended search space of novel and variant proteins in proteogenomic studies

por van de Geer, Wesley S, van Riet, Job, van de Werken, Harmen J G
Publicado 2021

Katdetectr: an R/bioconductor package utilizing unsupervised changepoint analysis for robust kataegis detection

por Hazelaar, Daan M, van Riet, Job, Hoogstrate, Youri, van de Werken, Harmen J G
Publicado 2023

A reported 20-gene expression signature to predict lymph node-positive disease at radical cystectomy for muscle-invasive bladder cancer is clinically not applicable

por van Kessel, Kim E. M., van de Werken, Harmen J. G., Lurkin, Irene, Ziel – van der Made, Angelique C. J., Zwarthoff, Ellen C., Boormans, Joost L.
Publicado 2017

Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines

por Wang, Wenhui, Liu, Pengyu, Lavrijsen, Marla, Li, Shan, Zhang, Ruyi, Li, Shanshan, van de Geer, Wesley S., van de Werken, Harmen J. G., Peppelenbosch, Maikel P., Smits, Ron
Publicado 2021

Personalised decision making to predict absolute metastatic risk in cutaneous squamous cell carcinoma: development and validation of a clinico-pathological model

por Rentroia-Pacheco, Barbara, Tokez, Selin, Bramer, Edo M., Venables, Zoe C., van de Werken, Harmen J.G., Bellomo, Domenico, van Klaveren, David, Mooyaart, Antien L., Hollestein, Loes M., Wakkee, Marlies
Publicado 2023

Landscape of driver gene events, biomarkers, and druggable targets identified by whole-genome sequencing of glioblastomas

por van de Geer, Wesley S, Hoogstrate, Youri, Draaisma, Kaspar, Robe, Pierre A, Bins, Sander, Mathijssen, Ron H J, French, Pim, van de Werken, Harmen J G, de Vos, Filip Y F
Publicado 2021

Endogenous WNT Signals Mediate BMP-Induced and Spontaneous Differentiation of Epiblast Stem Cells and Human Embryonic Stem Cells

por Kurek, Dorota, Neagu, Alex, Tastemel, Melodi, Tüysüz, Nesrin, Lehmann, Johannes, van de Werken, Harmen J.G., Philipsen, Sjaak, van der Linden, Reinier, Maas, Alex, van IJcken, Wilfred F.J., Drukker, Micha, ten Berge, Derk
Publicado 2014

Molecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development

por Dorssers, Lambert C. J., Gillis, Ad J. M., Stoop, Hans, van Marion, Ronald, Nieboer, Marleen M., van Riet, Job, van de Werken, Harmen J. G., Oosterhuis, J. Wolter, de Ridder, Jeroen, Looijenga, Leendert H. J.
Publicado 2019

The mouse KLF1 Nan variant impairs nuclear condensation and erythroid maturation

por Cantú, Ileana, van de Werken, Harmen J. G., Gillemans, Nynke, Stadhouders, Ralph, Heshusius, Steven, Maas, Alex, Esteghamat, Fatemehsadat, Ozgur, Zeliha, van IJcken, Wilfred F. J., Grosveld, Frank, von Lindern, Marieke, Philipsen, Sjaak, van Dijk, Thamar B.
Publicado 2019

Chromosome 3p25.3 Gain Is Associated With Cisplatin Resistance and Is an Independent Predictor of Poor Outcome in Male Malignant Germ Cell Tumors

por Timmerman, Dennis M., Eleveld, Thomas F., Sriram, Sruthi, Dorssers, Lambert C.J., Gillis, Ad J.M., Schmidtova, Silvia, Kalavska, Katarina, van de Werken, Harmen J.G., Oing, Christoph, Honecker, Friedemann, Mego, Michal, Looijenga, Leendert H.J.
Publicado 2022

Evaluation of pre-processing methods for tear fluid proteomics using proximity extension assays

por Vergouwen, Daphne P. C., Schotting, Amber J., Endermann, Tanja, van de Werken, Harmen J. G., Grashof, Dwin G. B., Arumugam, Sinthuja, Nuijts, Rudy M. M. A., ten Berge, Josianne C., Rothova, Aniki, Schreurs, Marco W. J., Gijs, Marlies
Publicado 2023

The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets

por van Riet, Job, van de Werken, Harmen J. G., Cuppen, Edwin, Eskens, Ferry A. L. M., Tesselaar, Margot, van Veenendaal, Linde M., Klümpen, Heinz-Josef, Dercksen, Marcus W., Valk, Gerlof D., Lolkema, Martijn P., Sleijfer, Stefan, Mostert, Bianca
Publicado 2021

Ibrutinib directly reduces CD8+T cell exhaustion independent of BTK

por Li, Ling, Zhao, Manzhi, Kiernan, Caoimhe H., Castro Eiro, Melisa D., van Meurs, Marjan, Brouwers-Haspels, Inge, Wilmsen, Merel E. P., Grashof, Dwin G. B., van de Werken, Harmen J. G., Hendriks, Rudi W., Mueller, Yvonne M., Katsikis, Peter D.
Publicado 2023

Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells

por Holwerda, Sjoerd J. B., van de Werken, Harmen J. G., Ribeiro de Almeida, Claudia, Bergen, Ingrid M., de Bruijn, Marjolein J. W., Verstegen, Marjon J. A. M., Simonis, Marieke, Splinter, Erik, Wijchers, Patrick J., Hendriks, Rudi W., de Laat, Wouter
Publicado 2013

The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes

por Knoch, Tobias A., Wachsmuth, Malte, Kepper, Nick, Lesnussa, Michael, Abuseiris, Anis, Ali Imam, A. M., Kolovos, Petros, Zuin, Jessica, Kockx, Christel E. M., Brouwer, Rutger W. W., van de Werken, Harmen J. G., van IJcken, Wilfred F. J., Wendt, Kerstin S., Grosveld, Frank G.
Publicado 2016

Overcoming immune checkpoint blockade resistance in solid tumors with intermittent ITK inhibition

por Zhao, Manzhi, Li, Ling, Kiernan, Caoimhe H., Castro Eiro, Melisa D., Dammeijer, Floris, van Meurs, Marjan, Brouwers-Haspels, Inge, Wilmsen, Merel E. P., Grashof, Dwin G. B., van de Werken, Harmen J. G., Hendriks, Rudi W., Aerts, Joachim G., Mueller, Yvonne M., Katsikis, Peter D.
Publicado 2023

Small chromosomal regions position themselves autonomously according to their chromatin class

por van de Werken, Harmen J.G., Haan, Josien C., Feodorova, Yana, Bijos, Dominika, Weuts, An, Theunis, Koen, Holwerda, Sjoerd J.B., Meuleman, Wouter, Pagie, Ludo, Thanisch, Katharina, Kumar, Parveen, Leonhardt, Heinrich, Marynen, Peter, van Steensel, Bas, Voet, Thierry, de Laat, Wouter, Solovei, Irina, Joffe, Boris
Publicado 2017

Continued Androgen Signalling Inhibition improves Cabazitaxel Efficacy in Prostate Cancer

por Mout, Lisanne, van Royen, Martin E., de Ridder, Corrina, Stuurman, Debra, van de Geer, Wesley S., Marques, Rute, Buck, Stefan A.J., French, Pim J., van de Werken, Harmen J.G., Mathijssen, Ron H.J., de Wit, Ronald, Lolkema, Martijn P., van Weerden, Wytske M.
Publicado 2021

Hyperresponsive cytosolic DNA-sensing pathway in monocytes from primary Sjögren’s syndrome

por Huijser, Erika, Bodewes, Iris L A, Lourens, Mirthe S, van Helden-Meeuwsen, Cornelia G, van den Bosch, Thierry P P, Grashof, Dwin G B, van de Werken, Harmen J G, Lopes, Ana P, van Roon, Joel A G, van Daele, Paul L A, Brkic, Zana, Dik, Willem A, Versnel, Marjan A
Publicado 2022

The miR-200c/141-ZEB2-TGFb axis is aberrant in human T-cell prolymphocytic leukemia

por Erkeland, Stefan J., Stavast, Christiaan J., Schilperoord-Vermeulen, Joyce, Dal Collo, Giada, van de Werken, Harmen J.G., Leon, Leticia G., van Hoven-Beijen, Antoinette, van Zuijen, Iris, Mueller, Yvonne M., Bindels, Eric M., de Ridder, Dick, Kappers-Klunne, Mies C., van Lom, Kirsten, van der Velden, Vincent H.J., Langerak, Anton W.
Publicado 2021