Ribosome dysfunction in osteoarthritis

por van den Akker, Guus G.H., Caron, Marjolein M.J., Peffers, Mandy J., Welting, Tim J.M.
Publicado 2022

Increased TGF-β and BMP Levels and Improved Chondrocyte-Specific Marker Expression In Vitro under Cartilage-Specific Physiological Osmolarity

por Tan Timur, Ufuk, Caron, Marjolein, van den Akker, Guus, van der Windt, Anna, Visser, Jenny, van Rhijn, Lodewijk, Weinans, Harrie, Welting, Tim, Emans, Pieter, Jahr, Holger
Publicado 2019

Current Practice in Bicistronic IRES Reporter Use: A Systematic Review

por van den Akker, Guus Gijsbertus Hubert, Zacchini, Federico, Housmans, Bas Adrianus Catharina, van der Vloet, Laura, Caron, Marjolein Maria Johanna, Montanaro, Lorenzo, Welting, Tim Johannes Maria
Publicado 2021

Novel immortal human cell lines reveal subpopulations in the nucleus pulposus

por van den Akker, Guus GH, Surtel, Don AM, Cremers, Andy, Rodrigues-Pinto, Ricardo, Richardson, Stephen M, Hoyland, Judith A, van Rhijn, Lodewijk W, Welting, Tim JM, Voncken, Jan Willem
Publicado 2014

Novel Immortal Cell Lines Support Cellular Heterogeneity in the Human Annulus Fibrosus

por van den Akker, Guus G. H., Surtel, Don A. M., Cremers, Andy, Richardson, Stephen M., Hoyland, Judith A., van Rhijn, Lodewijk W., Voncken, Jan Willem, Welting, Tim J. M.
Publicado 2016

SMAD3 and SMAD4 have a more dominant role than SMAD2 in TGFβ-induced chondrogenic differentiation of bone marrow-derived mesenchymal stem cells

por de Kroon, Laurie M. G., Narcisi, Roberto, van den Akker, Guus G. H., Vitters, Elly L., Blaney Davidson, Esmeralda N., van Osch, Gerjo J. V. M., van der Kraan, Peter M.
Publicado 2017

BMP7 increases protein synthesis in SW1353 cells and determines rRNA levels in a NKX3-2-dependent manner

por Ripmeester, Ellen G. J., Welting, Tim J. M., van den Akker, Guus G. H., Surtel, Don A. M., Steijns, Jessica S. J., Cremers, Andy, van Rhijn, Lodewijk W., Caron, Marjolein M. J.
Publicado 2022

MK3 controls Polycomb target gene expression via negative feedback on ERK

por Prickaerts, Peggy, Niessen, Hanneke EC, Mouchel-Vielh, Emmanuèle, Dahlmans, Vivian EH, van den Akker, Guus GH, Geijselaers, Claudia, Adriaens, Michiel E, Spaapen, Frank, Takihara, Yoshihiro, Rapp, Ulf R, Peronnet, Frédérique, Voncken, Jan Willem
Publicado 2012

Sox9 Determines Translational Capacity During Early Chondrogenic Differentiation of ATDC5 Cells by Regulating Expression of Ribosome Biogenesis Factors and Ribosomal Proteins

por Caron, Marjolein M. J., Eveque, Maxime, Cillero-Pastor, Berta, Heeren, Ron M. A., Housmans, Bas, Derks, Kasper, Cremers, Andy, Peffers, Mandy J., van Rhijn, Lodewijk W., van den Akker, Guus, Welting, Tim J. M.
Publicado 2021

Osteoarthritis-Related Inflammation Blocks TGF-β’s Protective Effect on Chondrocyte Hypertrophy via (de)Phosphorylation of the SMAD2/3 Linker Region

por Thielen, Nathalie, Neefjes, Margot, Wiegertjes, Renske, van den Akker, Guus, Vitters, Elly, van Beuningen, Henk, Blaney Davidson, Esmeralda, Koenders, Marije, van Lent, Peter, van de Loo, Fons, van Caam, Arjan, van der Kraan, Peter
Publicado 2021

BMP7 reduces the fibrocartilage chondrocyte phenotype

por Ripmeester, Ellen G. J., Caron, Marjolein M. J., van den Akker, Guus G. H., Steijns, Jessica, Surtel, Don A. M., Cremers, Andy, Peeters, Laura C. W., van Rhijn, Lodewijk W., Welting, Tim J. M.
Publicado 2021

Adaptation of the protein translational apparatus during ATDC5 chondrogenic differentiation

por Steinbusch, Mandy M.F., van den Akker, Guus G.H., Cremers, Andy, Witlox, Adhiambo M.A., Staal, Heleen M., Peffers, Mandy J., van Rhijn, Lodewijk W., Caron, Marjolein M.J., Welting, Tim J.M.
Publicado 2022

Depletion of SNORA33 Abolishes ψ of 28S-U4966 and Affects the Ribosome Translational Apparatus

por Chabronova, Alzbeta, van den Akker, Guus, Housmans, Bas A. C., Caron, Marjolein M. J., Cremers, Andy, Surtel, Don A. M., Peffers, Mandy J., van Rhijn, Lodewijk W., Marchand, Virginie, Motorin, Yuri, Welting, Tim J. M.
Publicado 2023

Discovery of bone morphogenetic protein 7-derived peptide sequences that attenuate the human osteoarthritic chondrocyte phenotype

por Caron, Marjolein M.J., Ripmeester, Ellen G.J., van den Akker, Guus, Wijnands, Nina K.A. P., Steijns, Jessica, Surtel, Don A.M., Cremers, Andy, Emans, Pieter J., van Rhijn, Lodewijk W., Welting, Tim J.M.
Publicado 2021

The antiviral protein viperin regulates chondrogenic differentiation via CXCL10 protein secretion

por Steinbusch, Mandy M. F., Caron, Marjolein M. J., Surtel, Don A. M., van den Akker, Guus G. H., van Dijk, Paul J., Friedrich, Franziska, Zabel, Bernhard, van Rhijn, Lodewijk W., Peffers, Mandy J., Welting, Tim J. M.
Publicado 2019

The Immediate Early Gene Product EGR1 and Polycomb Group Proteins Interact in Epigenetic Programming during Chondrogenesis

por Spaapen, Frank, van den Akker, Guus G. H., Caron, Marjolein M. J., Prickaerts, Peggy, Rofel, Celine, Dahlmans, Vivian E. H., Surtel, Don A. M., Paulis, Yvette, Schweizer, Finja, Welting, Tim J. M., Eijssen, Lars M., Voncken, Jan Willem
Publicado 2013

Multi-Omic Temporal Landscape of Plasma and Synovial Fluid-Derived Extracellular Vesicles Using an Experimental Model of Equine Osteoarthritis

por Anderson, James R., Johnson, Emily, Jenkins, Rosalind, Jacobsen, Stine, Green, Daniel, Walters, Marie, Bundgaard, Louise, Hausmans, Bas A. C., van den Akker, Guus, Welting, Tim J. M., Chabronova, Alzbeta, Kharaz, Yalda A., Clarke, Emily J., James, Victoria, Peffers, Mandy J.
Publicado 2023

EGR1 controls divergent cellular responses of distinctive nucleus pulposus cell types

por van den Akker, Guus G. H., Surtel, Don A. M., Cremers, Andy, Hoes, Martijn F. G. A., Caron, Marjolein M., Richardson, Stephen M., Rodrigues-Pinto, Ricardo, van Rhijn, Lodewijk W., Hoyland, Judith A., Welting, Tim J. M., Voncken, Jan Willem
Publicado 2016

Uncovering pathways regulating chondrogenic differentiation of CHH fibroblasts

por Chabronova, Alzbeta, van den Akker, Guus G.H., Meekels-Steinbusch, Mandy M.F., Friedrich, Franziska, Cremers, Andy, Surtel, Don A.M., Peffers, Mandy J., van Rhijn, Lodewijk W., Lausch, Ekkehart, Zabel, Bernhard, Caron, Marjolein M.J., Welting, Tim J.M.
Publicado 2021