Quantitative analysis by next generation sequencing of hematopoietic stem and progenitor cells (LSK) and of splenic B cells transcriptomes from wild-type and Usp3-knockout mice

por Lancini, Cesare, Gargiulo, Gaetano, van den Berk, Paul C.M., Citterio, Elisabetta
Publicado 2016

Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation

por Krijger, Peter H.L., Langerak, Petra, van den Berk, Paul C.M., Jacobs, Heinz
Publicado 2009

Somatic hypermutation of immunoglobulin genes: lessons from proliferating cell nuclear antigen(K164R) mutant mice

por Langerak, Petra, Krijger, Peter H.L., Heideman, Marinus R., van den Berk, Paul C.M., Jacobs, Heinz
Publicado 2008

A/T mutagenesis in hypermutated immunoglobulin genes strongly depends on PCNA(K164) modification

por Langerak, Petra, Nygren, Anders O.H., Krijger, Peter H.L., van den Berk, Paul C.M., Jacobs, Heinz
Publicado 2007

PrimPol prevents APOBEC/AID family mediated DNA mutagenesis

por Pilzecker, Bas, Buoninfante, Olimpia Alessandra, Pritchard, Colin, Blomberg, Olga S., Huijbers, Ivo J., van den Berk, Paul C.M., Jacobs, Heinz
Publicado 2016

Differential Programming of B Cells in AID Deficient Mice

por Hogenbirk, Marc A., Heideman, Marinus R., Velds, Arno, van den Berk, Paul CM., Kerkhoven, Ron M., van Steensel, Bas, Jacobs, Heinz
Publicado 2013

Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage

por Wit, Niek, Buoninfante, Olimpia Alessandra, van den Berk, Paul C.M., Jansen, Jacob G., Hogenbirk, Marc A., de Wind, Niels, Jacobs, Heinz
Publicado 2015

Precision cancer therapy: profiting from tumor specific defects in the DNA damage tolerance system

por Buoninfante, Olimpia Alessandra, Pilzecker, Bas, Aslam, Muhammad Assad, Zavrakidis, Ioannis, van der Wiel, Rianne, van de Ven, Marieke, van den Berk, Paul C.M., Jacobs, Heinz
Publicado 2018

Tight regulation of ubiquitin-mediated DNA damage response by USP3 preserves the functional integrity of hematopoietic stem cells

por Lancini, Cesare, van den Berk, Paul C.M., Vissers, Joseph H.A., Gargiulo, Gaetano, Song, Ji-Ying, Hulsman, Danielle, Serresi, Michela, Tanger, Ellen, Blom, Marleen, Vens, Conchita, van Lohuizen, Maarten, Jacobs, Heinz, Citterio, Elisabetta
Publicado 2014