Mutational spectrum of ATRX aberrations in neuroblastoma and associated patient and tumor characteristics

por van Gerven, Michael R., Bozsaky, Eva, Matser, Yvette A. H., Vosseberg, Julian, Taschner‐Mandl, Sabine, Koster, Jan, Tytgat, Godelieve A. M., Molenaar, Jan J., van den Boogaard, Marlinde
Publicado 2022

Two opposing gene expression patterns within ATRX aberrant neuroblastoma

por van Gerven, Michael R., Schild, Linda, van Arkel, Jennemiek, Koopmans, Bianca, Broeils, Luuk A., Meijs, Loes A. M., van Oosterhout, Romy, van Noesel, Max M., Koster, Jan, van Hooff, Sander R., Molenaar, Jan J., van den Boogaard, Marlinde L.
Publicado 2023

Increased DUX4 expression during muscle differentiation correlates with decreased SMCHD1 protein levels at D4Z4

por Balog, Judit, Thijssen, Peter E., Shadle, Sean, Straasheijm, Kirsten R., van der Vliet, Patrick J., Krom, Yvonne D., van den Boogaard, Marlinde L., de Jong, Annika, F Lemmers, Richard J. L., Tawil, Rabi, Tapscott, Stephen J., van der Maarel, Silvère M.
Publicado 2015

Chromosome 11q loss and MYCN amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma

por Keller, Kaylee M., Eleveld, Thomas F., Schild, Linda, van den Handel, Kim, van den Boogaard, Marlinde, Amo-Addae, Vicky, Eising, Selma, Ober, Kimberley, Koopmans, Bianca, Looijenga, Leendert, Tytgat, Godelieve A.M., Ylstra, Bauke, Molenaar, Jan J., Dolman, M. Emmy M., van Hooff, Sander R.
Publicado 2022

The potential of PARP as a therapeutic target across pediatric solid malignancies

por Keller, Kaylee M., Koetsier, Joost, Schild, Linda, Amo-Addae, Vicky, Eising, Selma, van den Handel, Kim, Ober, Kimberley, Koopmans, Bianca, Essing, Anke, van den Boogaard, Marlinde L., Langenberg, Karin P. S., Jäger, Natalie, Kool, Marcel, Pfister, Stefan, Dolman, M. Emmy M., Molenaar, Jan J., van Hooff, Sander R.
Publicado 2023

Therapeutic vulnerabilities in the DNA damage response for the treatment of ATRX mutant neuroblastoma

por George, Sally L, Lorenzi, Federica, King, David, Hartlieb, Sabine, Campbell, James, Pemberton, Helen, Toprak, Umut H, Barker, Karen, Tall, Jennifer, da Costa, Barbara Martins, van den Boogaard, Marlinde L, Dolman, M Emmy M, Molenaar, Jan J, Bryant, Helen E, Westermann, Frank, Lord, Christopher J, Chesler, Louis
Publicado 2020

Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma

por van den Boogaard, Marlinde L., Oka, Rurika, Hakkert, Anne, Schild, Linda, Ebus, Marli E., van Gerven, Michael R., Zwijnenburg, Danny A., Molenaar, Piet, Hoyng, Lieke L., Dolman, M. Emmy M., Essing, Anke H. W., Koopmans, Bianca, Helleday, Thomas, Drost, Jarno, van Boxtel, Ruben, Versteeg, Rogier, Koster, Jan, Molenaar, Jan J.
Publicado 2021