The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1

por Menzies, Sam A, Volkmar, Norbert, van den Boomen, Dick JH, Timms, Richard T, Dickson, Anna S, Nathan, James A, Lehner, Paul J
Publicado 2018

Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants

por Greenwood, Edward JD, Matheson, Nicholas J, Wals, Kim, van den Boomen, Dick JH, Antrobus, Robin, Williamson, James C, Lehner, Paul J
Publicado 2016

The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER

por Stagg, Helen R., Thomas, Mair, van den Boomen, Dick, Wiertz, Emmanuel J.H.J., Drabkin, Harry A., Gemmill, Robert M., Lehner, Paul J.
Publicado 2009

MARCH6 and TRC8 facilitate the quality control of cytosolic and tail‐anchored proteins

por Stefanovic‐Barrett, Sandra, Dickson, Anna S, Burr, Stephen P, Williamson, James C, Lobb, Ian T, van den Boomen, Dick JH, Lehner, Paul J, Nathan, James A
Publicado 2018

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export

por van den Boomen, Dick J. H., Sienkiewicz, Agata, Berlin, Ilana, Jongsma, Marlieke L. M., van Elsland, Daphne M., Luzio, J. Paul, Neefjes, Jacques J. C., Lehner, Paul J.
Publicado 2020

Plasma Membrane Profiling Defines an Expanded Class of Cell Surface Proteins Selectively Targeted for Degradation by HCMV US2 in Cooperation with UL141

por Hsu, Jye-Lin, van den Boomen, Dick J. H., Tomasec, Peter, Weekes, Michael P., Antrobus, Robin, Stanton, Richard J., Ruckova, Eva, Sugrue, Daniel, Wilkie, Gavin S., Davison, Andrew J., Wilkinson, Gavin W. G., Lehner, Paul J.
Publicado 2015

A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease

por Lim, Kyungtae, Rutherford, Eimear N., Sun, Dawei, Van den Boomen, Dick J. H., Edgar, James R., Bang, Jae Hak, Matesic, Lydia E., Lee, Joo-Hyeon, Lehner, Paul J., Marciniak, Stefan J., Rawlins, Emma L., Dickens, Jennifer A.
Publicado 2023