Calibrating the Bacterial Growth Rate Speedometer: A Re-evaluation of the Relationship Between Basal ppGpp, Growth, and RNA Synthesis in Escherichia coli

por Imholz, Nicole C. E., Noga, Marek J., van den Broek, Niels J. F., Bokinsky, Gregory
Publicado 2020

A Protocol for Quantifying Lipid Peroxidation in Cellular Systems by F2-Isoprostane Analysis

por Labuschagne, Christiaan F., van den Broek, Niels J. F., Postma, Pjotr, Berger, Ruud, Brenkman, Arjan B.
Publicado 2013

Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex

por Mulder, Klaas W., Brenkman, Arjan B., Inagaki, Akiko, van den Broek, Niels J. F., Marc Timmers, H. Th.
Publicado 2007

Mdm2 Induces Mono-Ubiquitination of FOXO4

por Brenkman, Arjan B., de Keizer, Peter L. J., van den Broek, Niels J. F., Jochemsen, A. G., Burgering, Boudewijn M. Th.
Publicado 2008

Posttranslational Control of PlsB Is Sufficient To Coordinate Membrane Synthesis with Growth in Escherichia coli

por Noga, Marek J., Büke, Ferhat, van den Broek, Niels J. F., Imholz, Nicole C. E., Scherer, Nicole, Yang, Flora, Bokinsky, Gregory
Publicado 2020

SIRT1 Mediates FOXA2 Breakdown by Deacetylation in a Nutrient-Dependent Manner

por van Gent, Rogier, Di Sanza, Claudio, van den Broek, Niels J. F., Fleskens, Veerle, Veenstra, Aukje, Stout, Gerdine J., Brenkman, Arjan B.
Publicado 2014

Quantification of folate metabolism using transient metabolic flux analysis

por Tedeschi, Philip M, Johnson-Farley, Nadine, Lin, Hongxia, Shelton, Laura M, Ooga, Takushi, Mackay, Gillian, Van Den Broek, Niels, Bertino, Joseph R, Vazquez, Alexei
Publicado 2015

Phosphorylation of Not4p Functions Parallel to BUR2 to Regulate Resistance to Cellular Stresses in Saccharomyces cerevisiae

por Lau, Nga-Chi, Mulder, Klaas W., Brenkman, Arjan B., Mohammed, Shabaz, van den Broek, Niels J. F., Heck, Albert J. R., Timmers, H. Th. Marc
Publicado 2010

Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells

por Baenke, Franziska, Chaneton, Barbara, Smith, Matthew, Van Den Broek, Niels, Hogan, Kate, Tang, Haoran, Viros, Amaya, Martin, Matthew, Galbraith, Laura, Girotti, Maria R., Dhomen, Nathalie, Gottlieb, Eyal, Marais, Richard
Publicado 2015

Serine one-carbon catabolism with formate overflow

por Meiser, Johannes, Tumanov, Sergey, Maddocks, Oliver, Labuschagne, Christiaan Fred, Athineos, Dimitris, Van Den Broek, Niels, Mackay, Gillian M., Gottlieb, Eyal, Blyth, Karen, Vousden, Karen, Kamphorst, Jurre J., Vazquez, Alexei
Publicado 2016

Multi-omics & pathway analysis identify potential roles for tumor N-acetyl aspartate accumulation in murine models of castration-resistant prostate cancer

por Salji, Mark J., Blomme, Arnaud, Däbritz, J. Henry M., Repiscak, Peter, Lilla, Sergio, Patel, Rachana, Sumpton, David, van den Broek, Niels J.F., Daly, Ronan, Zanivan, Sara, Leung, Hing Y.
Publicado 2022

Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation

por Bulusu, Vinay, Tumanov, Sergey, Michalopoulou, Evdokia, van den Broek, Niels J., MacKay, Gillian, Nixon, Colin, Dhayade, Sandeep, Schug, Zachary T., Vande Voorde, Johan, Blyth, Karen, Gottlieb, Eyal, Vazquez, Alexei, Kamphorst, Jurre J.
Publicado 2017

Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism

por Stout, Gerdine J, Stigter, Edwin C A, Essers, Paul B, Mulder, Klaas W, Kolkman, Annemieke, Snijders, Dorien S, van den Broek, Niels J F, Betist, Marco C, Korswagen, Hendrik C, MacInnes, Alyson W, Brenkman, Arjan B
Publicado 2013

Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1

por Patel, Rachana, Fleming, Janis, Mui, Ernest, Loveridge, Carolyn, Repiscak, Peter, Blomme, Arnaud, Harle, Victoria, Salji, Mark, Ahmad, Imran, Teo, Katy, Hamdy, Freddie C, Hedley, Ann, van den Broek, Niels, Mackay, Gillian, Edwards, Joanne, Sansom, Owen J, Leung, Hing Y
Publicado 2018

Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis

por Cardaci, Simone, Zheng, Liang, MacKay, Gillian, van den Broek, Niels J.F., MacKenzie, Elaine D., Nixon, Colin, Stevenson, David, Tumanov, Sergey, Bulusu, Vinay, Kamphorst, Jurre J., Vazquez, Alexei, Fleming, Stewart, Schiavi, Francesca, Kalna, Gabriela, Blyth, Karen, Strathdee, Douglas, Gottlieb, Eyal
Publicado 2015

Cellular assays identify barriers impeding iron-sulfur enzyme activity in a non-native prokaryotic host

por D'Angelo, Francesca, Fernández-Fueyo, Elena, Garcia, Pierre Simon, Shomar, Helena, Pelosse, Martin, Manuel, Rita Rebelo, Büke, Ferhat, Liu, Siyi, van den Broek, Niels, Duraffourg, Nicolas, de Ram, Carol, Pabst, Martin, Bouveret, Emmanuelle, Gribaldo, Simonetta, Py, Béatrice, Ollagnier de Choudens, Sandrine, Barras, Frédéric, Bokinsky, Gregory
Publicado 2022

Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike

por Yu, Xiaodi, Juraszek, Jarek, Rutten, Lucy, Bakkers, Mark J. G., Blokland, Sven, Melchers, Jelle M., van den Broek, Niels J. F., Verwilligen, Annemiek Y. W., Abeywickrema, Pravien, Vingerhoets, Johan, Neefs, Jean-Marc, Bakhash, Shah A. Mohamed, Roychoudhury, Pavitra, Greninger, Alex, Sharma, Sujata, Langedijk, Johannes P. M.
Publicado 2023

Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

por Schug, Zachary T., Peck, Barrie, Jones, Dylan T., Zhang, Qifeng, Grosskurth, Shaun, Alam, Israt S., Goodwin, Louise M., Smethurst, Elizabeth, Mason, Susan, Blyth, Karen, McGarry, Lynn, James, Daniel, Shanks, Emma, Kalna, Gabriela, Saunders, Rebecca E., Jiang, Ming, Howell, Michael, Lassailly, Francois, Thin, May Zaw, Spencer-Dene, Bradley, Stamp, Gordon, van den Broek, Niels J.F., Mackay, Gillian, Bulusu, Vinay, Kamphorst, Jurre J., Tardito, Saverio, Strachan, David, Harris, Adrian L., Aboagye, Eric O., Critchlow, Susan E., Wakelam, Michael J.O., Schulze, Almut, Gottlieb, Eyal
Publicado 2015