Novel method for detecting complement C3 deposition on Staphylococcus aureus

por Wonfor, Toska, Li, Shuxian, Dunphy, Rhys W., Macpherson, Alex, van den Elsen, Jean, Laabei, Maisem
Publicado 2022

The Staphylococcus aureus Protein Sbi Acts as a Complement Inhibitor and Forms a Tripartite Complex with Host Complement Factor H and C3b

por Haupt, Katrin, Reuter, Michael, van den Elsen, Jean, Burman, Julia, Hälbich, Steffi, Richter, Julia, Skerka, Christine, Zipfel, Peter F.
Publicado 2008

Staphylococcus aureus Proteins Sbi and Efb Recruit Human Plasmin to Degrade Complement C3 and C3b

por Koch, Tina K., Reuter, Michael, Barthel, Diana, Böhm, Sascha, van den Elsen, Jean, Kraiczy, Peter, Zipfel, Peter F., Skerka, Christine
Publicado 2012

Structure-Function Analysis of the C3 Binding Region of Staphylococcus aureus Immune Subversion Protein Sbi

por Upadhyay, Abhishek, Burman, Julia D., Clark, Elizabeth A., Leung, Elisa, Isenman, David E., van den Elsen, Jean M. H., Bagby, Stefan
Publicado 2008

The rational design of affinity-attenuated OmCI for the purification of complement C5

por Macpherson, Alex, Liu, Xiaofeng, Dedi, Neesha, Kennedy, Jeffery, Carrington, Bruce, Durrant, Oliver, Heywood, Sam, van den Elsen, Jean, Lawson, Alastair D. G.
Publicado 2018

A structural basis for Staphylococcal complement subversion: X-ray structure of the complement-binding domain of Staphylococcus aureus protein Sbi in complex with ligand C3d

por Clark, Elizabeth A., Crennell, Susan, Upadhyay, Abhishek, Zozulya, Alexey V., Mackay, Julia D., Svergun, Dmitri I., Bagby, Stefan, van den Elsen, Jean M.H.
Publicado 2011

Enhanced oxidative stress and damage in glycated erythrocytes

por Turpin, Chloé, Catan, Aurélie, Guerin-Dubourg, Alexis, Debussche, Xavier, Bravo, Susana B., Álvarez, Ezequiel, Van Den Elsen, Jean, Meilhac, Olivier, Rondeau, Philippe, Bourdon, Emmanuel
Publicado 2020

The proximity of the N- and C- termini of bovine knob domains enable engineering of target specificity into polypeptide chains

por Hawkins, Alice, Joyce, Callum, Brady, Kevin, Hold, Adam, Smith, Alan, Knight, Michael, Howard, Conor, van den Elsen, Jean, Lawson, Alastair D.G., Macpherson, Alex
Publicado 2022

Isolation of antigen-specific, disulphide-rich knob domain peptides from bovine antibodies

por Macpherson, Alex, Scott-Tucker, Anthony, Spiliotopoulos, Anastasios, Simpson, Catherine, Staniforth, Justin, Hold, Adam, Snowden, James, Manning, Leah, van den Elsen, Jean, Lawson, Alastair D. G.
Publicado 2020

Analysis of protein glycation using fluorescent phenylboronate gel electrophoresis

por Pereira Morais, Marta P., Marshall, Dominic, Flower, Stephen E., Caunt, Christopher J., James, Tony D., Williams, Robert J., Waterfield, Nicholas R., van den Elsen, Jean M. H.
Publicado 2013

Staphylococcal Complement Evasion Protein Sbi Stabilises C3d Dimers by Inducing an N-Terminal Helix Swap

por Dunphy, Rhys W., Wahid, Ayla A., Back, Catherine R., Martin, Rebecca L., Watts, Andrew G., Dodson, Charlotte A., Crennell, Susan J., van den Elsen, Jean M. H.
Publicado 2022

Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer’s Disease

por Kassaar, Omar, Pereira Morais, Marta, Xu, Suying, Adam, Emily L., Chamberlain, Rosemary C., Jenkins, Bryony, James, Tony, Francis, Paul T., Ward, Stephen, Williams, Robert J., van den Elsen, Jean
Publicado 2017

Corrigendum: Macrophage Migration Inhibitory Factor is subjected to glucose modification and oxidation in Alzheimer’s Disease

por Kassaar, Omar, Pereira Morais, Marta, Xu, Suying, Adam, Emily L., Chamberlain, Rosemary C., Jenkins, Bryony, James, Tony D., Francis, Paul T., Ward, Stephen, Williams, Robert J., van den Elsen, Jean
Publicado 2017

Thermal stability, storage and release of proteins with tailored fit in silica

por Chen, Yun-Chu, Smith, Tristan, Hicks, Robert H., Doekhie, Aswin, Koumanov, Francoise, Wells, Stephen A., Edler, Karen J., van den Elsen, Jean, Holman, Geoffrey D., Marchbank, Kevin J., Sartbaeva, Asel
Publicado 2017

From genotype to phenotype: can systems biology be used to predict Staphylococcus aureus virulence?

por Priest, Nicholas K., Rudkin, Justine K., Feil, Edward J., van den Elsen, Jean M. H., Cheung, Ambrose, Peacock, Sharon J., Laabei, Maisem, Lucks, David A., Recker, Mario, Massey, Ruth C.
Publicado 2012

From Insect to Man: Photorhabdus Sheds Light on the Emergence of Human Pathogenicity

por Mulley, Geraldine, Beeton, Michael L., Wilkinson, Paul, Vlisidou, Isabella, Ockendon-Powell, Nina, Hapeshi, Alexia, Tobias, Nick J., Nollmann, Friederike I., Bode, Helge B., van den Elsen, Jean, ffrench-Constant, Richard H., Waterfield, Nicholas R.
Publicado 2015

Utilization of Staphylococcal Immune Evasion Protein Sbi as a Novel Vaccine Adjuvant

por Yang, Yi, Back, Catherine R., Gräwert, Melissa A., Wahid, Ayla A., Denton, Harriet, Kildani, Rebecca, Paulin, Joshua, Wörner, Kristin, Kaiser, Wolgang, Svergun, Dmitri I., Sartbaeva, Asel, Watts, Andrew G., Marchbank, Kevin J., van den Elsen, Jean M. H.
Publicado 2019

Serum albumin binding knob domains engineered within a V(H) framework III bispecific antibody format and as chimeric peptides

por Adams, Ralph, Joyce, Callum, Kuravskiy, Mikhail, Harrison, Katriona, Ahdash, Zainab, Balmforth, Matthew, Chia, Kelda, Marceddu, Cinzia, Coates, Matthew, Snowden, James, Goursaud, Emmanuel, Ménochet, Karelle, van den Elsen, Jean, Payne, Richard J., Lawson, Alastair D. G., Scott-Tucker, Anthony, Macpherson, Alex
Publicado 2023

The allosteric modulation of complement C5 by knob domain peptides

por Macpherson, Alex, Laabei, Maisem, Ahdash, Zainab, Graewert, Melissa A, Birtley, James R, Schulze, Monika-Sarah ED, Crennell, Susan, Robinson, Sarah A, Holmes, Ben, Oleinikovas, Vladas, Nilsson, Per H, Snowden, James, Ellis, Victoria, Mollnes, Tom Eirik, Deane, Charlotte M, Svergun, Dmitri, Lawson, Alastair DG, van den Elsen, Jean MH
Publicado 2021

Insights Into the Structure-Function Relationships of Dimeric C3d Fragments

por Wahid, Ayla A., Dunphy, Rhys W., Macpherson, Alex, Gibson, Beth G., Kulik, Liudmila, Whale, Kevin, Back, Catherine, Hallam, Thomas M., Alkhawaja, Bayan, Martin, Rebecca L., Meschede, Ingrid, Laabei, Maisem, Lawson, Alastair D. G., Holers, V. Michael, Watts, Andrew G., Crennell, Susan J., Harris, Claire L., Marchbank, Kevin J., van den Elsen, Jean M. H.
Publicado 2021