Unfolding and disentangling coronary vascular disease through genome-wide association studies

por Erdmann, Jeanette, van der Laan, Sander W
Publicado 2021

The Applications of Single-Cell RNA Sequencing in Atherosclerotic Disease

por Slenders, Lotte, Tessels, Daniëlle E., van der Laan, Sander W., Pasterkamp, Gerard, Mokry, Michal
Publicado 2022

PolarMorphism enables discovery of shared genetic variants across multiple traits from GWAS summary statistics

por von Berg, Joanna, ten Dam, Michelle, van der Laan, Sander W, de Ridder, Jeroen
Publicado 2022

Effect of tissue-grouped regulatory variants associated to type 2 diabetes in related secondary outcomes

por Hemerich, Daiane, Smit, Roelof A. J., Preuss, Michael, Stalbow, Lauren, van der Laan, Sander W., Asselbergs, Folkert W., van Setten, Jessica, Tragante, Vinicius
Publicado 2023

LoFTK: a framework for fully automated calculation of predicted Loss-of-Function variants and genes

por Alasiri, Abdulrahman, Karczewski, Konrad J., Cole, Brian, Loza, Bao-Li, Moore, Jason H., van der Laan, Sander W., Asselbergs, Folkert W., Keating, Brendan J., van Setten, Jessica
Publicado 2023

Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke

por von Berg, Joanna, van der Laan, Sander W., McArdle, Patrick F., Malik, Rainer, Kittner, Steven J., Mitchell, Braxton D., Worrall, Bradford B., de Ridder, Jeroen, Pulit, Sara L.
Publicado 2020

Polygenic Susceptibility of Aortic Aneurysms Associates to the Diameter of the Aneurysm Sac: the Aneurysm-Express Biobank Cohort

por van Laarhoven, Constance J. H. C. M., van Setten, Jessica, van Herwaarden, Joost A., Pasterkamp, Gerard, de Kleijn, Dominique P. V., de Borst, Gert J., van der Laan, Sander W.
Publicado 2019

An automatic entropy method to efficiently mask histology whole-slide images

por Song, Yipei, Cisternino, Francesco, Mekke, Joost M., de Borst, Gert J., de Kleijn, Dominique P. V., Pasterkamp, Gerard, Vink, Aryan, Glastonbury, Craig A., van der Laan, Sander W., Miller, Clint L.
Publicado 2023

Common Variants Associated With OSMR Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans

por van Keulen, Danielle, van Koeverden, Ian D., Boltjes, Arjan, Princen, Hans M. G., van Gool, Alain J., de Borst, Gert J., Asselbergs, Folkert W., Tempel, Dennie, Pasterkamp, Gerard, van der Laan, Sander W.
Publicado 2021

PlaqView 2.0: A comprehensive web portal for cardiovascular single-cell genomics

por Ma, Wei Feng, Turner, Adam W., Gancayco, Christina, Wong, Doris, Song, Yipei, Mosquera, Jose Verdezoto, Auguste, Gaëlle, Hodonsky, Chani J., Prabhakar, Ajay, Ekiz, H. Atakan, van der Laan, Sander W., Miller, Clint L.
Publicado 2022

Characteristics of peripheral blood cells are independently related to major adverse cardiovascular events after carotid endarterectomy

por Overmars, L. Malin, Mekke, Joost M., van Solinge, Wouter W., De Jager, Saskia C.A., Hulsbergen-Veelken, Cornelia A.R., Hoefer, Imo E., de Kleijn, Dominique P.V., de Borst, Gert J., van der Laan, Sander W., Haitjema, Saskia
Publicado 2023

X chromosome inactivation skewing is common in advanced carotid atherosclerotic lesions in females and predicts secondary peripheral artery events

por Buono, Michele F., Benavente, Ernest Diez, Daniels, Mark, Mol, Barend M., Mekke, Joost M., de Borst, Gert J., de Kleijn, Dominique P. V., van der Laan, Sander W., Pasterkamp, Gerard, Onland-Moret, Charlotte, Mokry, Michal, den Ruijter, Hester M.
Publicado 2023

Common Genetic Variation in MC4R Does Not Affect Atherosclerotic Plaque Phenotypes and Cardiovascular Disease Outcomes

por Blauw, Lisanne L., Noordam, Raymond, van der Laan, Sander W., Trompet, Stella, Kooijman, Sander, van Heemst, Diana, Jukema, Johan Wouter, van Setten, Jessica, de Borst, Gert J., Tybjærg-Hansen, Anne, Pasterkamp, Gerard, Berbée, Jimmy F. P., Rensen, Patrick C. N.
Publicado 2021

Proteogenomic integration reveals CXCL10 as a potentially downstream causal mediator for IL-6 signaling on atherosclerosis

por Prapiadou, Savvina, Živković, Luka, Thorand, Barbara, George, Marc J., van der Laan, Sander W., Malik, Rainer, Herder, Christian, Koenig, Wolfgang, Ueland, Thor, Kleveland, Ola, Aukrust, Pal, Gullestad, Lars, Bernhagen, Jürgen, Pasterkamp, Gerard, Peters, Annette, Hingorani, Aroon D., Rosand, Jonathan, Dichgans, Martin, Anderson, Christopher D., Georgakis, Marios K.
Publicado 2023

The accumulation of erythrocytes quantified and visualized by Glycophorin C in carotid atherosclerotic plaque reflects intraplaque hemorrhage and pre-procedural neurological sympt...

por Mekke, Joost M., Sakkers, Tim R., Verwer, Maarten C., van den Dungen, Noortje A. M., Song, Yipei, Miller, Clint L., Finn, Aloke V., Pasterkamp, Gerard, Mokry, Michal, den Ruijter, Hester M., Vink, Aryan, de Kleijn, Dominique P. V., de Borst, Gert J., Haitjema, Saskia, van der Laan, Sander W.
Publicado 2023

Functional investigation of the coronary artery disease gene SVEP1

por Winkler, Michael J., Müller, Philipp, Sharifi, Amin M., Wobst, Jana, Winter, Hanna, Mokry, Michal, Ma, Lijiang, van der Laan, Sander W., Pang, Shichao, Miritsch, Benedikt, Hinterdobler, Julia, Werner, Julia, Stiller, Barbara, Güldener, Ulrich, Webb, Tom R., Asselbergs, Folkert W., Björkegren, Johan L. M., Maegdefessel, Lars, Schunkert, Heribert, Sager, Hendrik B., Kessler, Thorsten
Publicado 2020

Leukotriene B4 Levels in Human Atherosclerotic Plaques and Abdominal Aortic Aneurysms

por van den Borne, Pleunie, van der Laan, Sander W., Bovens, Sandra M., Koole, Dave, Kowala, Mark C., Michael, Laura F., Schoneveld, Arjan H., van de Weg, Sander M., Velema, Evelyn, de Vries, Jean-Paul, de Borst, Gert J., Moll, Frans L., de Kleijn, Dominique P. V., Quax, Paul H. A., Hoefer, Imo E., Pasterkamp, Gerard
Publicado 2014

Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity

por Schmidt, Amand F., Bourfiss, Mimount, Alasiri, Abdulrahman, Puyol-Anton, Esther, Chopade, Sandesh, van Vugt, Marion, van der Laan, Sander W., Gross, Christian, Clarkson, Chris, Henry, Albert, Lumbers, Tom R., van der Harst, Pim, Franceschini, Nora, Bis, Joshua C., Velthuis, Birgitta K., te Riele, Anneline S. J. M., Hingorani, Aroon D., Ruijsink, Bram, Asselbergs, Folkert W., van Setten, Jessica, Finan, Chris
Publicado 2023

Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes

por Theofilatos, Konstantinos, Stojkovic, Stefan, Hasman, Maria, van der Laan, Sander W., Baig, Ferheen, Barallobre-Barreiro, Javier, Schmidt, Lukas Emanuel, Yin, Siqi, Yin, Xiaoke, Burnap, Sean, Singh, Bhawana, Popham, Jude, Harkot, Olesya, Kampf, Stephanie, Nackenhorst, Maja Carina, Strassl, Andreas, Loewe, Christian, Demyanets, Svitlana, Neumayer, Christoph, Bilban, Martin, Hengstenberg, Christian, Huber, Kurt, Pasterkamp, Gerard, Wojta, Johann, Mayr, Manuel
Publicado 2023

Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets

por Lempiäinen, Harri, Brænne, Ingrid, Michoel, Tom, Tragante, Vinicius, Vilne, Baiba, Webb, Tom R., Kyriakou, Theodosios, Eichner, Johannes, Zeng, Lingyao, Willenborg, Christina, Franzen, Oscar, Ruusalepp, Arno, Goel, Anuj, van der Laan, Sander W., Biegert, Claudia, Hamby, Stephen, Talukdar, Husain A., Foroughi Asl, Hassan, Pasterkamp, Gerard, Watkins, Hugh, Samani, Nilesh J., Wittenberger, Timo, Erdmann, Jeanette, Schunkert, Heribert, Asselbergs, Folkert W., Björkegren, Johan L. M.
Publicado 2018