Artificial intelligence in pharmacology research and practice

por van der Lee, Maaike, Swen, Jesse J.
Publicado 2022

Technologies for Pharmacogenomics: A Review

por van der Lee, Maaike, Kriek, Marjolein, Guchelaar, Henk-Jan, Swen, Jesse J.
Publicado 2020

Why We Need to Take a Closer Look at Genetic Contributions to CYP3A Activity

por Zhai, Qinglian, van der Lee, Maaike, van Gelder, Teun, Swen, Jesse J.
Publicado 2022

Study protocol of the HD-MED study aiming to personalize drug treatment in Huntington’s disease: a longitudinal, observational study to assess medication use and efficacy in relati...

por Feleus, Stephanie, van der Lee, Maaike, Swen, Jesse J., Roos, Raymund A. C., de Bot, Susanne T.
Publicado 2023

Application of long-read sequencing to elucidate complex pharmacogenomic regions: a proof of principle

por van der Lee, Maaike, Rowell, William J., Menafra, Roberta, Guchelaar, Henk-Jan, Swen, Jesse J., Anvar, Seyed Yahya
Publicado 2021

From gene to dose: Long-read sequencing and *-allele tools to refine phenotype predictions of CYP2C19

por Graansma, Lonneke J., Zhai, Qinglian, Busscher, Loes, Menafra, Roberta, van den Berg, Redmar R., Kloet, Susan L., van der Lee, Maaike
Publicado 2023

Development of an extensive workflow for comprehensive clinical pharmacogenomic profiling: lessons from a pilot study on 100 whole exome sequencing data

por Tafazoli, Alireza, van der Lee, Maaike, Swen, Jesse J., Zeller, Anna, Wawrusiewicz-Kurylonek, Natalia, Mei, Hailiang, Vorderman, Ruben H. P., Konopko, Krzysztof, Zankiewicz, Andrzej, Miltyk, Wojciech
Publicado 2022

Physiologically based pharmacokinetic modeling of tacrolimus for food–drug and CYP3A drug–drug–gene interaction predictions

por Loer, Helena Leonie Hanae, Feick, Denise, Rüdesheim, Simeon, Selzer, Dominik, Schwab, Matthias, Teutonico, Donato, Frechen, Sebastian, van der Lee, Maaike, Moes, Dirk Jan A. R., Swen, Jesse J., Lehr, Thorsten
Publicado 2023

Repurposing of Diagnostic Whole Exome Sequencing Data of 1,583 Individuals for Clinical Pharmacogenetics

por van der Lee, Maaike, Allard, William G., Bollen, Sander, Santen, Gijs W. E., Ruivenkamp, Claudia A. L., Hoffer, Mariëtte J. V., Kriek, Marjolein, Guchelaar, Henk‐Jan, Anvar, Seyed Y., Swen, Jesse J.
Publicado 2019

Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network

por Feick, Denise, Rüdesheim, Simeon, Marok, Fatima Zahra, Selzer, Dominik, Loer, Helena Leonie Hanae, Teutonico, Donato, Frechen, Sebastian, van der Lee, Maaike, Moes, Dirk Jan A. R., Swen, Jesse J., Schwab, Matthias, Lehr, Thorsten
Publicado 2023