Carboxylesterase 1d (Ces1d) does not contribute to cholesteryl ester hydrolysis in the liver

por Lian, Jihong, van der Veen, Jelske N., Watts, Russell, Jacobs, René L., Lehner, Richard
Publicado 2021

Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase

por van der Veen, Jelske N., Lingrell, Susanne, Gao, Xia, Takawale, Abhijit, Kassiri, Zamaneh, Vance, Dennis E., Jacobs, René L.
Publicado 2017

Impaired Hepatic Phosphatidylcholine Synthesis Leads to Cholestasis in Mice Challenged With a High‐Fat Diet

por Wan, Sereana, Kuipers, Folkert, Havinga, Rick, Ando, Hiromi, Vance, Dennis E., Jacobs, René L., van der Veen, Jelske N.
Publicado 2019

Intestinal Phospholipid Disequilibrium Initiates an ER Stress Response That Drives Goblet Cell Necroptosis and Spontaneous Colitis in Mice

por Kennelly, John P., Carlin, Stephanie, Ju, Tingting, van der Veen, Jelske N., Nelson, Randal C., Buteau, Jean, Thiesen, Aducio, Richard, Caroline, Willing, Ben P., Jacobs, René L.
Publicado 2020

Genetic screening reveals phospholipid metabolism as a key regulator of the biosynthesis of the redox-active lipid coenzyme Q

por Ayer, Anita, Fazakerley, Daniel J., Suarna, Cacang, Maghzal, Ghassan J., Sheipouri, Diba, Lee, Kevin J., Bradley, Michelle C., Fernández-del-Rio, Lucía, Tumanov, Sergey, Kong, Stephanie MY., van der Veen, Jelske N., Yang, Andrian, Ho, Joshua W.K., Clarke, Steven G., James, David E., Dawes, Ian W., Vance, Dennis E., Clarke, Catherine F., Jacobs, René L., Stocker, Roland
Publicado 2021

Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression

por Trzaskalski, Natasha A., Vulesevic, Branka, Nguyen, My-Anh, Jeraj, Natasha, Fadzeyeva, Evgenia, Morrow, Nadya M., Locatelli, Cassandra A.A., Travis, Nicole, Hanson, Antonio A., Nunes, Julia R.C., O’Dwyer, Conor, van der Veen, Jelske N., Lorenzen-Schmidt, Ilka, Seymour, Rick, Pulente, Serena M., Clément, Andrew C., Crawley, Angela M., Jacobs, René L., Doyle, Mary-Anne, Cooper, Curtis L., Kim, Kyoung-Han, Fullerton, Morgan D., Mulvihill, Erin E.
Publicado 2023