Single-cell RNA sequencing identifies cell type-specific cis-eQTLs and co-expression QTLs

por van der Wijst, Monique G.P., Brugge, Harm, de Vries, Dylan H., Deelen, Patrick, Swertz, Morris A., Franke, Lude
Publicado em 2018

Integration of Candida albicans-induced single-cell gene expression data and secretory protein concentrations reveal genetic regulators of inflammation

por Boahen, Collins K., Oelen, Roy, Le, Kieu, Netea, Mihai G., Franke, Lude, van der Wijst, Monique G.P., Kumar, Vinod
Publicado em 2023

Critical changes in hypothalamic gene networks in response to pancreatic cancer as found by single-cell RNA sequencing

por Huisman, Christian, Norgard, Mason A., Levasseur, Peter R., Krasnow, Stephanie M., van der Wijst, Monique G.P., Olson, Brennan, Marks, Daniel L.
Publicado em 2022

Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell data

por Li, Shuang, Schmid, Katharina T., de Vries, Dylan H., Korshevniuk, Maryna, Losert, Corinna, Oelen, Roy, van Blokland, Irene V., Groot, Hilde E., Swertz, Morris A., van der Harst, Pim, Westra, Harm-Jan, van der Wijst, Monique G.P., Heinig, Matthias, Franke, Lude
Publicado em 2023

Deconvolution of bulk blood eQTL effects into immune cell subpopulations

por Aguirre-Gamboa, Raúl, de Klein, Niek, di Tommaso, Jennifer, Claringbould, Annique, van der Wijst, Monique GP, de Vries, Dylan, Brugge, Harm, Oelen, Roy, Võsa, Urmo, Zorro, Maria M., Chu, Xiaojin, Bakker, Olivier B., Borek, Zuzanna, Ricaño-Ponce, Isis, Deelen, Patrick, Xu, Cheng-Jiang, Swertz, Morris, Jonkers, Iris, Withoff, Sebo, Joosten, Irma, Sanna, Serena, Kumar, Vinod, Koenen, Hans J. P. M., Joosten, Leo A. B., Netea, Mihai G., Wijmenga, Cisca, Franke, Lude, Li, Yang
Publicado em 2020

Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19: Anti-IFN antibodies in critical COVID...

por van der Wijst, Monique G.P., Vazquez, Sara E., Hartoularos, George C., Bastard, Paul, Grant, Tianna, Bueno, Raymund, Lee, David S., Greenland, John R., Sun, Yang, Perez, Richard, Ogorodnikov, Anton, Ward, Alyssa, Mann, Sabrina A., Lynch, Kara L., Yun, Cassandra, Havlir, Diane V., Chamie, Gabriel, Marquez, Carina, Greenhouse, Bryan, Lionakis, Michail S., Norris, Philip J., Dumont, Larry J., Kelly, Kathleen, Zhang, Peng, Zhang, Qian, Gervais, Adrian, Le Voyer, Tom, Whatley, Alexander, Si, Yichen, Byrne, Ashley, Combes, Alexis J., Rao, Arjun Arkal, Song, Yun S., Fragiadakis, Gabriela K., Kangelaris, Kirsten, Calfee, Carolyn S., Erle, David J., Hendrickson, Carolyn, Krummel, Matthew F., Woodruff, Prescott G., Langelier, Charles R., Casanova, Jean-Laurent, Derisi, Joseph L., Anderson, Mark S., Ye, Chun Jimmie
Publicado em 2021

A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling

por Hackney, Jason A., Shivram, Haridha, Vander Heiden, Jason, Overall, Chris, Orozco, Luz, Gao, Xia, Kim, Eugene, West, Nathan, Qamra, Aditi, Chang, Diana, Chakrabarti, Arindam, Choy, David F., Combes, Alexis J., Courau, Tristan, Fragiadakis, Gabriela K., Rao, Arjun Arkal, Ray, Arja, Tsui, Jessica, Hu, Kenneth, Kuhn, Nicholas F., Krummel, Matthew F., Erle, David J., Kangelaris, Kirsten, Sarma, Aartik, Lyon, Zoe, Calfee, Carolyn S., Woodruff, Prescott G., Ghale, Rajani, Mick, Eran, Byrne, Ashley, Zha, Beth Shoshana, Langelier, Charles, Hendrickson, Carolyn M., van der Wijst, Monique G.P., Hartoularos, George C., Grant, Tianna, Bueno, Raymund, Lee, David S., Greenland, John R., Sun, Yang, Perez, Richard, Ogorodnikov, Anton, Ward, Alyssa, Ye, Chun Jimmie, Ramalingam, Thiru, McBride, Jacqueline M., Cai, Fang, Teterina, Anastasia, Bao, Min, Tsai, Larry, Rosas, Ivan O., Regev, Aviv, Kapadia, Sharookh B., Bauer, Rebecca N., Rosenberger, Carrie M.
Publicado em 2023

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

por Võsa, Urmo, Claringbould, Annique, Westra, Harm-Jan, Bonder, Marc Jan, Deelen, Patrick, Zeng, Biao, Kirsten, Holger, Saha, Ashis, Kreuzhuber, Roman, Yazar, Seyhan, Brugge, Harm, Oelen, Roy, de Vries, Dylan H., van der Wijst, Monique G.P., Kasela, Silva, Pervjakova, Natalia, Alves, Isabel, Favé, Marie-Julie, Agbessi, Mawussé, Christiansen, Mark W., Jansen, Rick, Seppälä, Ilkka, Tong, Lin, Teumer, Alexander, Schramm, Katharina, Hemani, Gibran, Verlouw, Joost, Yaghootkar, Hanieh, Sönmez, Reyhan, Brown, Andrew, Kukushkina, Viktorija, Kalnapenkis, Anette, Rüeger, Sina, Porcu, Eleonora, Kronberg, Jaanika, Kettunen, Johannes, Lee, Bernett, Zhang, Futao, Qi, Ting, Hernandez, Jose Alquicira, Arindrarto, Wibowo, Beutner, Frank, Dmitrieva, Julia, Elansary, Mahmoud, Fairfax, Benjamin P., Georges, Michel, Heijmans, Bastiaan T., Hewitt, Alex W., Kähönen, Mika, Kim, Yungil, Knight, Julian C., Kovacs, Peter, Krohn, Knut, Li, Shuang, Loeffler, Markus, Marigorta, Urko M., Mei, Hailang, Momozawa, Yukihide, Müller-Nurasyid, Martina, Nauck, Matthias, Nivard, Michel G., Penninx, Brenda WJH., Pritchard, Jonathan K., Raitakari, Olli T., Rotzschke, Olaf, Slagboom, Eline P., Stehouwer, Coen D.A., Stumvoll, Michael, Sullivan, Patrick, ‘t Hoen, Peter A.C., Thiery, Joachim, Tönjes, Anke, van Dongen, Jenny, van Iterson, Maarten, Veldink, Jan H., Völker, Uwe, Warmerdam, Robert, Wijmenga, Cisca, Swertz, Morris, Andiappan, Anand, Montgomery, Grant W., Ripatti, Samuli, Perola, Markus, Kutalik, Zoltan, Dermitzakis, Emmanouil, Bergmann, Sven, Frayling, Timothy, van Meurs, Joyce, Prokisch, Holger, Ahsan, Habibul, Pierce, Brandon L., Lehtimäki, Terho, Boomsma, Dorret I., Psaty, Bruce M., Gharib, Sina A., Awadalla, Philip, Milani, Lili, Ouwehand, Willem H., Downes, Kate, Stegle, Oliver, Battle, Alexis, Visscher, Peter M., Yang, Jian, Scholz, Markus, Powell, Joseph, Gibson, Greg, Esko, Tõnu, Franke, Lude
Publicado em 2021