Assessment of radiation damage behaviour in a large collection of empirically optimized datasets highlights the importance of unmeasured complicating effects

por Krojer, Tobias, von Delft, Frank
Publicado 2011

Molecular replacement

por Murshudov, Garib, von Delft, Frank, Ballard, Charles
Publicado 2008

Crystal structures of human soluble guanylate cyclase catalytic domains: promiscuity of the dimer interface and a potential allosteric site

por Gileadi, Opher, Allerston, Charles, von Delft, Frank
Publicado 2013

Defined PEG smears as an alternative approach to enhance the search for crystallization conditions and crystal-quality improvement in reduced screens

por Chaikuad, Apirat, Knapp, Stefan, von Delft, Frank
Publicado 2015

Structural Basis for ASPP2 Recognition by the Tumor Suppressor p73

por Canning, Peter, von Delft, Frank, Bullock, Alex N.
Publicado 2012

Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase

por Allerston, Charles K., von Delft, Frank, Gileadi, Opher
Publicado 2013

Proper modelling of ligand binding requires an ensemble of bound and unbound states

por Pearce, Nicholas M., Krojer, Tobias, von Delft, Frank
Publicado 2017

Squeezing the most from every crystal: the fine details of data collection

por Krojer, Tobias, Pike, Ashley C. W., von Delft, Frank
Publicado 2013

Targeting the Small GTPase Superfamily through Their Regulatory Proteins

por Gray, Janine L., von Delft, Frank, Brennan, Paul E.
Publicado 2020

Lessons from ten years of crystallization experiments at the SGC

por Ng, Jia Tsing, Dekker, Carien, Reardon, Paul, von Delft, Frank
Publicado 2016

Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension

por Chaikuad, Apirat, Thangaratnarajah, Chancievan, von Delft, Frank, Bullock, Alex N.
Publicado 2019

Fragment Libraries Designed to Be Functionally Diverse Recover Protein Binding Information More Efficiently Than Standard Structurally Diverse Libraries

por Carbery, Anna, Skyner, Rachael, von Delft, Frank, Deane, Charlotte M.
Publicado 2022

Using textons to rank crystallization droplets by the likely presence of crystals

por Ng, Jia Tsing, Dekker, Carien, Kroemer, Markus, Osborne, Michael, von Delft, Frank
Publicado 2014

Galaxy workflows for fragment-based virtual screening: a case study on the SARS-CoV-2 main protease

por Bray, Simon, Dudgeon, Tim, Skyner, Rachael, Backofen, Rolf, Grüning, Björn, von Delft, Frank
Publicado 2022

RHO to the DOCK for GDP disembarking: Structural insights into the DOCK GTPase nucleotide exchange factors

por Thompson, Andrew P., Bitsina, Christina, Gray, Janine L., von Delft, Frank, Brennan, Paul E.
Publicado 2021

Crystal Structures of ABL-Related Gene (ABL2) in Complex with Imatinib, Tozasertib (VX-680), and a Type I Inhibitor of the Triazole Carbothioamide Class

por Salah, Eidarus, Ugochukwu, Emilie, Barr, Alastair J., von Delft, Frank, Knapp, Stefan, Elkins, Jonathan M.
Publicado 2011

An overview of heavy-atom derivatization of protein crystals

por Pike, Ashley C. W., Garman, Elspeth F., Krojer, Tobias, von Delft, Frank, Carpenter, Elisabeth P.
Publicado 2016

Crystal structure of the catalytic D2 domain of the AAA+ ATPase p97 reveals a putative helical split‐washer‐type mechanism for substrate unfolding

por Stach, Lasse, Morgan, Rhodri Marc, Makhlouf, Linda, Douangamath, Alice, von Delft, Frank, Zhang, Xiaodong, Freemont, Paul S.
Publicado 2019

SAMPL7 protein-ligand challenge: A community-wide evaluation of computational methods against fragment screening and pose-prediction

por Grosjean, Harold, Işık, Mehtap, Aimon, Anthony, Mobley, David, Chodera, John, von Delft, Frank, Biggin, Philip C
Publicado 2022

A small molecule targeting ALK1 prevents Notch cooperativity and inhibits functional angiogenesis

por Kerr, Georgina, Sheldon, Helen, Chaikuad, Apirat, Alfano, Ivan, von Delft, Frank, Bullock, Alex N., Harris, Adrian L.
Publicado 2015