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Neurodegeneration and neuroprotection in Parkinson's disease /
Otros Autores: | , , |
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Formato: | Libro |
Lenguaje: | English |
Publicado: |
London ; San Diego :
Academic Press,
c1996.
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Colección: | Neuroscience perspectives
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Materias: |
Tabla de Contenidos:
- Sect.1. Oxidant stress
- Oxidative stress, brain iron and neurodegeneration. Basic principles
- Pathological evidence for oxidative stress in Parkinson's disease and related degenerative disorders
- Treatment of Parkinson's disease with deprenyl (selegiline) and other monoamine oxidase inhibitors
- Iron and neurodegeneration: prospects for neuroprotection
- Nitrone radical traps protect in experimental neurodegenerative diseases
- Therapeutic effects of nitric oxide synthase inhibition in neuronal injury
- Sect.2. Mitochondrial toxicity
- Mitochondrial dysfunction in neurodegernation: prospects for neuroprotection
- Sect.3. Excitatory neurotoxicity
- Bioenergetics and excitotoxicity: the weak excitotoxic hypothesis
- Sect.4. Calcium excitatory toxicity
- Calcium ions in necrotic and apoptotic cell death
- Sect.5. Trophic factors
- Neurotrophic factors: towards a restorative therapy of Parkinson's disease
- Sect.6. Immune mechanisms
- Immune-mediated cell death and neuroprotection in neurodegenerative diseases
- Sect.7. Apoptosis
- Reduction of neuronal apoptosis by small molecules: promise for new approaches to neurological therapy
- Index.