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Neurodegeneration and neuroprotection in Parkinson's disease /

Detalles Bibliográficos
Otros Autores: Olanow, C. W. (Charles Warren), 1941-, Jenner, Peter, 1946-, Youdim, Moussa B. H.
Formato: Libro
Lenguaje:English
Publicado: London ; San Diego : Academic Press, c1996.
Colección:Neuroscience perspectives
Materias:
Tabla de Contenidos:
  • Sect.1. Oxidant stress
  • Oxidative stress, brain iron and neurodegeneration. Basic principles
  • Pathological evidence for oxidative stress in Parkinson's disease and related degenerative disorders
  • Treatment of Parkinson's disease with deprenyl (selegiline) and other monoamine oxidase inhibitors
  • Iron and neurodegeneration: prospects for neuroprotection
  • Nitrone radical traps protect in experimental neurodegenerative diseases
  • Therapeutic effects of nitric oxide synthase inhibition in neuronal injury
  • Sect.2. Mitochondrial toxicity
  • Mitochondrial dysfunction in neurodegernation: prospects for neuroprotection
  • Sect.3. Excitatory neurotoxicity
  • Bioenergetics and excitotoxicity: the weak excitotoxic hypothesis
  • Sect.4. Calcium excitatory toxicity
  • Calcium ions in necrotic and apoptotic cell death
  • Sect.5. Trophic factors
  • Neurotrophic factors: towards a restorative therapy of Parkinson's disease
  • Sect.6. Immune mechanisms
  • Immune-mediated cell death and neuroprotection in neurodegenerative diseases
  • Sect.7. Apoptosis
  • Reduction of neuronal apoptosis by small molecules: promise for new approaches to neurological therapy
  • Index.