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Molecular targeting in oncology /
"In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application. The volume covers the complexity of the rapidly developing area of targeted therapies for the treatment of patients wit...
| Otros Autores: | , , |
|---|---|
| Formato: | Libro |
| Lenguaje: | English |
| Publicado: |
Totowa, N.J. :
Humana,
c2008.
|
| Colección: | Cancer drug discovery and development.
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| Materias: | |
| Acceso en línea: | Tabla de contenido |
MARC
| LEADER | 00000cam a2200000Ia 4500 | ||
|---|---|---|---|
| 001 | ocn213133228 | ||
| 003 | OCoLC | ||
| 005 | 20150815145112.0 | ||
| 008 | 120925s2008 njua b 001 0 eng | ||
| 035 | |a (Sirsi) i9781588295774 | ||
| 040 | |a UKM |c UKM |d UV# | ||
| 020 | |a 9781588295774 | ||
| 020 | |a 158829577X | ||
| 050 | 0 | 4 | |a RC271.C5 |b M64 2008 |
| 082 | 0 | 4 | |a 616.994061 |2 22 |
| 245 | 0 | 0 | |a Molecular targeting in oncology / |c edited by Howard L. Kaufman, Scott Wadler, Karen Antman. |
| 260 | |a Totowa, N.J. : |b Humana, |c c2008. | ||
| 300 | |a xvi, 728 páginas : |b ilustraciones ; |c 26 cm. | ||
| 490 | 1 | |a Cancer drug discovery and development | |
| 504 | |a Incluye bibliografías e índice. | ||
| 505 | 0 | 0 | |t Cell cycle : therapeutic targeting of cell cycle regulatory components and effector pathways in cancer / |r Chad D. Knights and Richard G. Pestell -- |t mTOR : properties and therapeutics / |r John B. Easton and Peter J. Houghton -- |t Ras/Raf/MEK inhibitors / |r Joseph A. Sparano -- |t 17-AAG : targeting the molecular chaperone heat shock protein 90 / |r Len Neckers and Percy Ivy -- |t Cancer epigenome : can it be targeted for therapy / |r Sam Thiagalingam and Douglas V. Faller -- |t Molecular targeting in upper gastrointestinal malignancies / |r Scott Wadler -- |t Molecular targeting of colorectal cancer : an idea whose time has come / |r Mark L. Sundermeyer, Alfonso Bellacosa, and Neal J. Meropol -- |t Molecular targeting in hepatocellular carcinoma / |r Jonathan D. Schwartz and Josep M. Llovet -- |t Molecularly targeted therapy in pancreatic cancer / |r Anupama Goel and Peter Kozuch -- |t Untargeted use of targeted therapy : a dilemma in non-small cell lung cancer / |r Cheryl Ho ... [et al.] -- |t Renal cell carcinoma : renal cell cancer / |r Olwen Hahn and Walter Stadler -- |t Targeted therapies for prostate cancer / |r Elisabeth I. Heath and Michael A. Carducci -- |t Molecular targets in ovarian cancer and endometrial cancer / |r Nilofer S. Azad, Gisele Sarosy, and Elise C. Kohn -- |t Targeted therapy for breast cancer / |r Deena M. Atich and Linda T. Vahdat -- |t Melanoma / |r Akshay Gupta and John M. Kirkwood -- |t Antibody therapy of cancer / |r Hossein Borghaei ... [et al.] -- |t Nucleic acid therapies for cancer treatment / |r Dan T. Vogl and Alan M. Gewirtz -- |t Engineering oncolytic measles viruses for targeted cancer therapy / |r Takafumi Nakamura and Stephen J. Russell -- |t Vaccines as targeted cancer therapy / |r Miguel-Angel Perales, Jedd D. wolchok, and Howard L. Kaufman -- |t Cytokine-based therapy for cancer / |r Henry B. Koon and Michael B. Atkins -- |t Cyclooxygenase-2 as a target for cancer prevention and treatment / |r Monica Bertagnolli, Jaye L. Viner, and Ernest T. Hawk -- |t Imatinib mesylate (Gleevec) and the emergence of chemotherapeutic drug-resistant mutations / |r Gerald V. Denis -- |t Development of a targeted treatment for cancer : the example of C225 (cetuximab) / |r John Mendelsohn -- |t VEGF inhibition for cancer therapy / |r Shermini Saini and Herbert Hurwitz -- |t Somatostatin analogue therapy / |r M. C. Champaneria ... [et al.] -- |t Patient selection for rational development of novel anticancer agents / |r Grace K. Dy and Alex A. Adjei -- |t Clinical trial design with targeted agents / |r Sarita Dubey and Joan H. Schiller -- |t How to define treatment success or failure if tumors do not shrink : consequences for trial design / |r J. J. E. M. Kitzen, M. J. A. de Jonge, and J. Verweij -- |t Molecular imaging in oncology / |r Lalitha K. Shankar, Anne Menkens, and Daniel C. Sullivan -- |t Combinations of molecular-targeted therapies : opportunities and challenges / |r Helen X. Chen and Janet E. Dancey -- |t Preclinical development of molecularly targeted agents in oncology / |r Joseph E. Tomaszewski and James H. Doroshow. |
| 520 | |a "In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application. The volume covers the complexity of the rapidly developing area of targeted therapies for the treatment of patients with cancer and is structured in a way so readers may begin with chapters that most interest them and work through the rest of the chapters in the order of their choice. The volume is divided into five sections that cover the most important elements of drug development. The first section focuses on approaches using targeted therapies to inhibit cell growth. The second section describes how clinicians are evaluating targeted therapies in specific organ systems. The third section illustrates how various classes of pharmacologic and immunologic agents are developed for individual molecular targets. The fourth section details new drugs that have novel mechanisms of action. The final section looks to the future of targeted therapeutics and includes chapters on appropriate patient selection, use of combination therapy, dealing with tumor cell resistance, and more."--Publisher | ||
| 650 | 4 | |a Cáncer |x Quimioterapia. | |
| 650 | 4 | |a Cáncer |x Aspectos moleculares. | |
| 650 | 4 | |a Agentes antineoplásicos |x Farmacología. | |
| 700 | 1 | |a Kaufman, Howard L. |9 401384 | |
| 700 | 1 | |a Wadler, Scott, |d d. 2007. | |
| 700 | 1 | |a Antman, Karen. |9 411026 | |
| 830 | 0 | |a Cancer drug discovery and development. | |
| 856 | 4 | 1 | |3 Tabla de contenido |u http://catdir.loc.gov/catdir/enhancements/fy0825/2007932637-t.html |
| 901 | |a Z0 |b UV# | ||
| 596 | |a 2 | ||
| 942 | |c LIBRO |6 _ | ||
| 999 | |c 259502 |d 259502 | ||