The FLUKA code for application of Monte Carlo methods to promote high precision ion beam therapy

Monte Carlo (MC) methods are increasingly being utilized to support several aspects of commissioning and clinical operation of ion beam therapy facilities. In this contribution two emerging areas of MC applications are outlined. The value of MC modeling to promote accurate treatment planning is addr...

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Detalles Bibliográficos
Autores principales: Parodi, K, Brons, S, Cerutti, F, Ferrari, A, Mairani, A, Paganetti, H, Sommerer, F
Lenguaje:eng
Publicado: 2010
Materias:
Health Physics and Radiation Effects
Computing and Computers
Acceso en línea:http://cds.cern.ch/record/1238366
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author Parodi, K
Brons, S
Cerutti, F
Ferrari, A
Mairani, A
Paganetti, H
Sommerer, F
author_facet Parodi, K
Brons, S
Cerutti, F
Ferrari, A
Mairani, A
Paganetti, H
Sommerer, F
author_sort Parodi, K
collection CERN
description Monte Carlo (MC) methods are increasingly being utilized to support several aspects of commissioning and clinical operation of ion beam therapy facilities. In this contribution two emerging areas of MC applications are outlined. The value of MC modeling to promote accurate treatment planning is addressed via examples of application of the FLUKA code to proton and carbon ion therapy at the Heidelberg Ion Beam Therapy Center in Heidelberg, Germany, and at the Proton Therapy Center of Massachusetts General Hospital (MGH) Boston, USA. These include generation of basic data for input into the treatment planning system (TPS) and validation of the TPS analytical pencil-beam dose computations. Moreover, we review the implementation of PET/CT (Positron-Emission-Tomography / Computed- Tomography) imaging for in-vivo verification of proton therapy at MGH. Here, MC is used to calculate irradiation-induced positron-emitter production in tissue for comparison with the +-activity measurement in order to infer indirect information on the actual dose delivery.
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institution Organización Europea para la Investigación Nuclear
language eng
publishDate 2010
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spelling cern-12383662019-09-30T06:29:59Zhttp://cds.cern.ch/record/1238366engParodi, KBrons, SCerutti, FFerrari, AMairani, APaganetti, HSommerer, FThe FLUKA code for application of Monte Carlo methods to promote high precision ion beam therapyHealth Physics and Radiation EffectsComputing and ComputersMonte Carlo (MC) methods are increasingly being utilized to support several aspects of commissioning and clinical operation of ion beam therapy facilities. In this contribution two emerging areas of MC applications are outlined. The value of MC modeling to promote accurate treatment planning is addressed via examples of application of the FLUKA code to proton and carbon ion therapy at the Heidelberg Ion Beam Therapy Center in Heidelberg, Germany, and at the Proton Therapy Center of Massachusetts General Hospital (MGH) Boston, USA. These include generation of basic data for input into the treatment planning system (TPS) and validation of the TPS analytical pencil-beam dose computations. Moreover, we review the implementation of PET/CT (Positron-Emission-Tomography / Computed- Tomography) imaging for in-vivo verification of proton therapy at MGH. Here, MC is used to calculate irradiation-induced positron-emitter production in tissue for comparison with the +-activity measurement in order to infer indirect information on the actual dose delivery.oai:cds.cern.ch:12383662010
spellingShingle Health Physics and Radiation Effects
Computing and Computers
Parodi, K
Brons, S
Cerutti, F
Ferrari, A
Mairani, A
Paganetti, H
Sommerer, F
The FLUKA code for application of Monte Carlo methods to promote high precision ion beam therapy
title The FLUKA code for application of Monte Carlo methods to promote high precision ion beam therapy
title_full The FLUKA code for application of Monte Carlo methods to promote high precision ion beam therapy
title_fullStr The FLUKA code for application of Monte Carlo methods to promote high precision ion beam therapy
title_full_unstemmed The FLUKA code for application of Monte Carlo methods to promote high precision ion beam therapy
title_short The FLUKA code for application of Monte Carlo methods to promote high precision ion beam therapy
title_sort fluka code for application of monte carlo methods to promote high precision ion beam therapy
topic Health Physics and Radiation Effects
Computing and Computers
url http://cds.cern.ch/record/1238366
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