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Development of a High Precision Axial 3-D PET for Brain Imaging

We describe a PET device based on a novel method to extract the coordinates of the interaction point of the 511 keV γ rays from 100 mm long and thin LYSO (Lutetium Yttrium OxyorthoSilicate) scintillator bars, positioned axially in the tomograph. The coordinate along the hit crystal is measured by us...

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Detalles Bibliográficos
Autores principales: Bolle, E, Braem, A, Casella, C, Chesi, E, Clinthorne, N, Cochran, E, De Leo, R, Dissertori, G, Djambazov, L, Honscheid, K, Huh, S, Johnson, I, Joram, C, Kagan, H, Lacasta, C, Lustermann, W, Meddi, F, Nappi, E, Nessi-Tedaldi, F, Oliver, J F, Pauss, F, Rafecas, M, Renker, D, Rudge, A, Schinzel, D, Schneider, T, Séguinot, J, Smith, S, Solevi, P, Stapnes, S, Vilardi, I, Weilhammer, P
Lenguaje:eng
Publicado: 2009
Materias:
Acceso en línea:https://dx.doi.org/10.1016/j.nuclphysbps.2009.10.026
http://cds.cern.ch/record/1260967
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author Bolle, E
Braem, A
Casella, C
Chesi, E
Clinthorne, N
Cochran, E
De Leo, R
Dissertori, G
Djambazov, L
Honscheid, K
Huh, S
Johnson, I
Joram, C
Kagan, H
Lacasta, C
Lustermann, W
Meddi, F
Nappi, E
Nessi-Tedaldi, F
Oliver, J F
Pauss, F
Rafecas, M
Renker, D
Rudge, A
Schinzel, D
Schneider, T
Séguinot, J
Smith, S
Solevi, P
Stapnes, S
Vilardi, I
Weilhammer, P
author_facet Bolle, E
Braem, A
Casella, C
Chesi, E
Clinthorne, N
Cochran, E
De Leo, R
Dissertori, G
Djambazov, L
Honscheid, K
Huh, S
Johnson, I
Joram, C
Kagan, H
Lacasta, C
Lustermann, W
Meddi, F
Nappi, E
Nessi-Tedaldi, F
Oliver, J F
Pauss, F
Rafecas, M
Renker, D
Rudge, A
Schinzel, D
Schneider, T
Séguinot, J
Smith, S
Solevi, P
Stapnes, S
Vilardi, I
Weilhammer, P
author_sort Bolle, E
collection CERN
description We describe a PET device based on a novel method to extract the coordinates of the interaction point of the 511 keV γ rays from 100 mm long and thin LYSO (Lutetium Yttrium OxyorthoSilicate) scintillator bars, positioned axially in the tomograph. The coordinate along the hit crystal is measured by using a hodoscope of Wave Length Shifting (WLS) plastic strips mounted perpendicularly to each plane of scintillators. As photodetectors, new Geiger mode Avalanche PhotoDetectors (G-APDs) with integrated electronics are being used to detect both the hit crystal in a block (x and y coordinates) and the interaction point in the crystal (z coordinate) through the light escaping from the crystal and transmitted to the WLS strips. In this way, the γ interaction point can be determined with a spatial resolution of few cubic millimeters down to a minimum deposited energy of about 50 keV, resulting in a volumetric precision very close to the limits imposed by the physics of the positron annihilation. The method allows to increase the detection efficiency without affecting the spatial resolution by adding scintillator planes in the radial direction. A demonstrator scanner, based on two matrices of 8 ×6 LYSO crystals and 312 WLS strips, slotted in between the crystals, is under construction. Preliminary results from the feasibility studies of the various components will be presented.
id cern-1260967
institution Organización Europea para la Investigación Nuclear
language eng
publishDate 2009
record_format invenio
spelling cern-12609672019-09-30T06:29:59Zdoi:10.1016/j.nuclphysbps.2009.10.026http://cds.cern.ch/record/1260967engBolle, EBraem, ACasella, CChesi, EClinthorne, NCochran, EDe Leo, RDissertori, GDjambazov, LHonscheid, KHuh, SJohnson, IJoram, CKagan, HLacasta, CLustermann, WMeddi, FNappi, ENessi-Tedaldi, FOliver, J FPauss, FRafecas, MRenker, DRudge, ASchinzel, DSchneider, TSéguinot, JSmith, SSolevi, PStapnes, SVilardi, IWeilhammer, PDevelopment of a High Precision Axial 3-D PET for Brain ImagingDetectors and Experimental TechniquesWe describe a PET device based on a novel method to extract the coordinates of the interaction point of the 511 keV γ rays from 100 mm long and thin LYSO (Lutetium Yttrium OxyorthoSilicate) scintillator bars, positioned axially in the tomograph. The coordinate along the hit crystal is measured by using a hodoscope of Wave Length Shifting (WLS) plastic strips mounted perpendicularly to each plane of scintillators. As photodetectors, new Geiger mode Avalanche PhotoDetectors (G-APDs) with integrated electronics are being used to detect both the hit crystal in a block (x and y coordinates) and the interaction point in the crystal (z coordinate) through the light escaping from the crystal and transmitted to the WLS strips. In this way, the γ interaction point can be determined with a spatial resolution of few cubic millimeters down to a minimum deposited energy of about 50 keV, resulting in a volumetric precision very close to the limits imposed by the physics of the positron annihilation. The method allows to increase the detection efficiency without affecting the spatial resolution by adding scintillator planes in the radial direction. A demonstrator scanner, based on two matrices of 8 ×6 LYSO crystals and 312 WLS strips, slotted in between the crystals, is under construction. Preliminary results from the feasibility studies of the various components will be presented.oai:cds.cern.ch:12609672009
spellingShingle Detectors and Experimental Techniques
Bolle, E
Braem, A
Casella, C
Chesi, E
Clinthorne, N
Cochran, E
De Leo, R
Dissertori, G
Djambazov, L
Honscheid, K
Huh, S
Johnson, I
Joram, C
Kagan, H
Lacasta, C
Lustermann, W
Meddi, F
Nappi, E
Nessi-Tedaldi, F
Oliver, J F
Pauss, F
Rafecas, M
Renker, D
Rudge, A
Schinzel, D
Schneider, T
Séguinot, J
Smith, S
Solevi, P
Stapnes, S
Vilardi, I
Weilhammer, P
Development of a High Precision Axial 3-D PET for Brain Imaging
title Development of a High Precision Axial 3-D PET for Brain Imaging
title_full Development of a High Precision Axial 3-D PET for Brain Imaging
title_fullStr Development of a High Precision Axial 3-D PET for Brain Imaging
title_full_unstemmed Development of a High Precision Axial 3-D PET for Brain Imaging
title_short Development of a High Precision Axial 3-D PET for Brain Imaging
title_sort development of a high precision axial 3-d pet for brain imaging
topic Detectors and Experimental Techniques
url https://dx.doi.org/10.1016/j.nuclphysbps.2009.10.026
http://cds.cern.ch/record/1260967
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