Searches for New Heavy Quarks with the CMS Detector at the LHC

We review the capability of the CMS experiment to address the experimental searches for New Heavy Quarks at the LHC. In particular, we concentrate on the first year(s) of LHC operations, since new physics at the TeV scale may manifest itself even in modest data samples of the order of a few hundreds pb$^{-1}$. A few example searches for New Heavy Quarks are discussed, with emphasis on processes characterized by clean final states with electrons and muons.