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CERN-MEDICIS (MEDical Isotopes Collected from ISOLDE): A new facility

About 50% of the 1.4GeV CERN’s protons are sent onto targets to produce radioactive beams by online mass separation at ISOLDE, for a wide range of studies in fundamental and applied physics. CERN-MEDICIS is a spin-off dedicated to R&D in life sciences and medical applications. It is located in a...

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Autores principales: Augusto, Ricardo Manuel dos Santos, Buehler, Leo, Lawson, Zoe, Marzari, Stefano, Stachura, Monika, Stora, Thierry
Lenguaje:eng
Publicado: 2014
Materias:
Acceso en línea:https://dx.doi.org/10.3390/app4020265
http://cds.cern.ch/record/1670694
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author Augusto, Ricardo Manuel dos Santos
Buehler, Leo
Lawson, Zoe
Marzari, Stefano
Stachura, Monika
Stora, Thierry
author_facet Augusto, Ricardo Manuel dos Santos
Buehler, Leo
Lawson, Zoe
Marzari, Stefano
Stachura, Monika
Stora, Thierry
author_sort Augusto, Ricardo Manuel dos Santos
collection CERN
description About 50% of the 1.4GeV CERN’s protons are sent onto targets to produce radioactive beams by online mass separation at ISOLDE, for a wide range of studies in fundamental and applied physics. CERN-MEDICIS is a spin-off dedicated to R&D in life sciences and medical applications. It is located in an extension of the Class A building presently under construction. It will comprise laboratories to receive the irradiated targets from a new station located at the dump position behind the ISOLDE production targets. An increasing range of innovative isotopes will thus progressively become accessible from the start-up of the facility in 2015 onward; for fundamental studies in cancer research, for new imaging and therapy protocols in cell and animal models and for pre-clinical trials, possibly extended to specific early phase clinical studies up to phase I trials. 500 MBq isotope batches purified by electromagnetic mass separation combined with chemical methods will be collected on a weekly basis. Possible future upgrade with GBq pharmaceutical-grade (i.e., cGMP) batch production capabilities is finally presented.
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institution Organización Europea para la Investigación Nuclear
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publishDate 2014
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spelling cern-16706942019-09-30T06:29:59Zdoi:10.3390/app4020265http://cds.cern.ch/record/1670694engAugusto, Ricardo Manuel dos SantosBuehler, LeoLawson, ZoeMarzari, StefanoStachura, MonikaStora, ThierryCERN-MEDICIS (MEDical Isotopes Collected from ISOLDE): A new facilityHealth Physics and Radiation EffectsNuclear Physics - ExperimentAbout 50% of the 1.4GeV CERN’s protons are sent onto targets to produce radioactive beams by online mass separation at ISOLDE, for a wide range of studies in fundamental and applied physics. CERN-MEDICIS is a spin-off dedicated to R&D in life sciences and medical applications. It is located in an extension of the Class A building presently under construction. It will comprise laboratories to receive the irradiated targets from a new station located at the dump position behind the ISOLDE production targets. An increasing range of innovative isotopes will thus progressively become accessible from the start-up of the facility in 2015 onward; for fundamental studies in cancer research, for new imaging and therapy protocols in cell and animal models and for pre-clinical trials, possibly extended to specific early phase clinical studies up to phase I trials. 500 MBq isotope batches purified by electromagnetic mass separation combined with chemical methods will be collected on a weekly basis. Possible future upgrade with GBq pharmaceutical-grade (i.e., cGMP) batch production capabilities is finally presented.CERN-ACC-NOTE-2014-0019oai:cds.cern.ch:16706942014-01-23
spellingShingle Health Physics and Radiation Effects
Nuclear Physics - Experiment
Augusto, Ricardo Manuel dos Santos
Buehler, Leo
Lawson, Zoe
Marzari, Stefano
Stachura, Monika
Stora, Thierry
CERN-MEDICIS (MEDical Isotopes Collected from ISOLDE): A new facility
title CERN-MEDICIS (MEDical Isotopes Collected from ISOLDE): A new facility
title_full CERN-MEDICIS (MEDical Isotopes Collected from ISOLDE): A new facility
title_fullStr CERN-MEDICIS (MEDical Isotopes Collected from ISOLDE): A new facility
title_full_unstemmed CERN-MEDICIS (MEDical Isotopes Collected from ISOLDE): A new facility
title_short CERN-MEDICIS (MEDical Isotopes Collected from ISOLDE): A new facility
title_sort cern-medicis (medical isotopes collected from isolde): a new facility
topic Health Physics and Radiation Effects
Nuclear Physics - Experiment
url https://dx.doi.org/10.3390/app4020265
http://cds.cern.ch/record/1670694
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