Cargando…

Fundamentals of bioinformatics and computational biology: methods and exercises in matlab

This book offers comprehensive coverage of all the core topics of bioinformatics, and includes practical examples completed using the MATLAB bioinformatics toolbox™. It is primarily intended as a textbook for engineering and computer science students attending advanced undergraduate and graduate cou...

Descripción completa

Detalles Bibliográficos
Autor principal: Singh, Gautam B
Lenguaje:eng
Publicado: Springer 2015
Materias:
Acceso en línea:https://dx.doi.org/10.1007/978-3-319-11403-3
http://cds.cern.ch/record/1968772
_version_ 1780944689490296832
author Singh, Gautam B
author_facet Singh, Gautam B
author_sort Singh, Gautam B
collection CERN
description This book offers comprehensive coverage of all the core topics of bioinformatics, and includes practical examples completed using the MATLAB bioinformatics toolbox™. It is primarily intended as a textbook for engineering and computer science students attending advanced undergraduate and graduate courses in bioinformatics and computational biology. The book develops bioinformatics concepts from the ground up, starting with an introductory chapter on molecular biology and genetics. This chapter will enable physical science students to fully understand and appreciate the ultimate goals of applying the principles of information technology to challenges in biological data management, sequence analysis, and systems biology. The first part of the book also includes a survey of existing biological databases, tools that have become essential in today’s biotechnology research. The second part of the book covers methodologies for retrieving biological information, including fundamental algorithms for sequence comparison, scoring, and determining evolutionary distance. The main focus of the third part is on modeling biological sequences and patterns as Markov chains. It presents key principles for analyzing and searching for sequences of significant motifs and biomarkers. The last part of the book, dedicated to systems biology, covers phylogenetic analysis and evolutionary tree computations, as well as gene expression analysis with microarrays. In brief, the book offers the ideal hands-on reference guide to the field of bioinformatics and computational biology.  
id cern-1968772
institution Organización Europea para la Investigación Nuclear
language eng
publishDate 2015
publisher Springer
record_format invenio
spelling cern-19687722021-04-21T20:49:47Zdoi:10.1007/978-3-319-11403-3http://cds.cern.ch/record/1968772engSingh, Gautam BFundamentals of bioinformatics and computational biology: methods and exercises in matlabEngineeringThis book offers comprehensive coverage of all the core topics of bioinformatics, and includes practical examples completed using the MATLAB bioinformatics toolbox™. It is primarily intended as a textbook for engineering and computer science students attending advanced undergraduate and graduate courses in bioinformatics and computational biology. The book develops bioinformatics concepts from the ground up, starting with an introductory chapter on molecular biology and genetics. This chapter will enable physical science students to fully understand and appreciate the ultimate goals of applying the principles of information technology to challenges in biological data management, sequence analysis, and systems biology. The first part of the book also includes a survey of existing biological databases, tools that have become essential in today’s biotechnology research. The second part of the book covers methodologies for retrieving biological information, including fundamental algorithms for sequence comparison, scoring, and determining evolutionary distance. The main focus of the third part is on modeling biological sequences and patterns as Markov chains. It presents key principles for analyzing and searching for sequences of significant motifs and biomarkers. The last part of the book, dedicated to systems biology, covers phylogenetic analysis and evolutionary tree computations, as well as gene expression analysis with microarrays. In brief, the book offers the ideal hands-on reference guide to the field of bioinformatics and computational biology.  Springeroai:cds.cern.ch:19687722015
spellingShingle Engineering
Singh, Gautam B
Fundamentals of bioinformatics and computational biology: methods and exercises in matlab
title Fundamentals of bioinformatics and computational biology: methods and exercises in matlab
title_full Fundamentals of bioinformatics and computational biology: methods and exercises in matlab
title_fullStr Fundamentals of bioinformatics and computational biology: methods and exercises in matlab
title_full_unstemmed Fundamentals of bioinformatics and computational biology: methods and exercises in matlab
title_short Fundamentals of bioinformatics and computational biology: methods and exercises in matlab
title_sort fundamentals of bioinformatics and computational biology: methods and exercises in matlab
topic Engineering
url https://dx.doi.org/10.1007/978-3-319-11403-3
http://cds.cern.ch/record/1968772
work_keys_str_mv AT singhgautamb fundamentalsofbioinformaticsandcomputationalbiologymethodsandexercisesinmatlab