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Monte Carlo Latching Studies of Prompt-Gamma Detection During Hadrontherapy

Proton and carbon therapies of a human brain were simulated using FLUKA, with particular emphasis on treatment monitoring using the prompt gamma method where activities of the source proton/carbon in the patient's body are to be extracted from the positional profile of exit photons. Tissue hete...

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Detalles Bibliográficos
Autores principales: Chin, M P W, Cerutti, F, Ferrari, A, Ortega, P G, Sala, P R
Lenguaje:eng
Publicado: 2014
Materias:
XX
Acceso en línea:https://dx.doi.org/10.1109/TNS.2014.2356553
http://cds.cern.ch/record/2120680
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author Chin, M P W
Cerutti, F
Ferrari, A
Ortega, P G
Sala, P R
author_facet Chin, M P W
Cerutti, F
Ferrari, A
Ortega, P G
Sala, P R
author_sort Chin, M P W
collection CERN
description Proton and carbon therapies of a human brain were simulated using FLUKA, with particular emphasis on treatment monitoring using the prompt gamma method where activities of the source proton/carbon in the patient's body are to be extracted from the positional profile of exit photons. Tissue heterogeneity ranging from hydrogen to zinc was represented in a VIP-Man anthropomorphic voxel phantom. Each photon exiting the head was scored with ancestry attributes such as the particle type of its parent, the originating collision type and site. These data, not accessible via physical detectors, were analysed to characterise the escaping photons, delineating signal from noise according to the gamma origin and scatter history. Combinations of energy, geometry, time and angle filters, aided by raytracing, were studied for the optimal compromise between a sufficiently featured exit profile and a statistically adequate count. These will be put in context with ongoing research in the field; our perspective for the prompt gamma method will be discussed in detail.
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institution Organización Europea para la Investigación Nuclear
language eng
publishDate 2014
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spelling cern-21206802019-09-30T06:29:59Zdoi:10.1109/TNS.2014.2356553http://cds.cern.ch/record/2120680engChin, M P WCerutti, FFerrari, AOrtega, P GSala, P RMonte Carlo Latching Studies of Prompt-Gamma Detection During HadrontherapyXXProton and carbon therapies of a human brain were simulated using FLUKA, with particular emphasis on treatment monitoring using the prompt gamma method where activities of the source proton/carbon in the patient's body are to be extracted from the positional profile of exit photons. Tissue heterogeneity ranging from hydrogen to zinc was represented in a VIP-Man anthropomorphic voxel phantom. Each photon exiting the head was scored with ancestry attributes such as the particle type of its parent, the originating collision type and site. These data, not accessible via physical detectors, were analysed to characterise the escaping photons, delineating signal from noise according to the gamma origin and scatter history. Combinations of energy, geometry, time and angle filters, aided by raytracing, were studied for the optimal compromise between a sufficiently featured exit profile and a statistically adequate count. These will be put in context with ongoing research in the field; our perspective for the prompt gamma method will be discussed in detail.oai:cds.cern.ch:21206802014
spellingShingle XX
Chin, M P W
Cerutti, F
Ferrari, A
Ortega, P G
Sala, P R
Monte Carlo Latching Studies of Prompt-Gamma Detection During Hadrontherapy
title Monte Carlo Latching Studies of Prompt-Gamma Detection During Hadrontherapy
title_full Monte Carlo Latching Studies of Prompt-Gamma Detection During Hadrontherapy
title_fullStr Monte Carlo Latching Studies of Prompt-Gamma Detection During Hadrontherapy
title_full_unstemmed Monte Carlo Latching Studies of Prompt-Gamma Detection During Hadrontherapy
title_short Monte Carlo Latching Studies of Prompt-Gamma Detection During Hadrontherapy
title_sort monte carlo latching studies of prompt-gamma detection during hadrontherapy
topic XX
url https://dx.doi.org/10.1109/TNS.2014.2356553
http://cds.cern.ch/record/2120680
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