Cargando…

The FLUKA code: An accurate simulation tool for particle therapy

Monte Carlo (MC) codes are increasingly spreading in the hadrontherapy community due to their detailed description of radiation transport and interaction with matter. The suitability of a MC code for application to hadrontherapy demands accurate and reliable physical models capable of handling all c...

Descripción completa

Detalles Bibliográficos
Autores principales: Battistoni, Giuseppe, Bauer, Julia, Böhlen, Till T, Cerutti, Francesco, Chin, Mary Pik Wai, Dos Santos Augusto, Ricardo M, Ferrari, Alfredo, Garcia Ortega, Pablo, Kozlowska, Wioletta S, Magro, Giuseppe, Mairani, Andrea, Parodi, Katia, Sala, Paola R, Schoofs, Philippe, Tessonnier, Thomas, Vlachoudis, Vasilis
Lenguaje:eng
Publicado: 2016
Materias:
Acceso en línea:https://dx.doi.org/10.3389/fonc.2016.00116
http://cds.cern.ch/record/2150047
_version_ 1780950445552828416
author Battistoni, Giuseppe
Bauer, Julia
Böhlen, Till T
Cerutti, Francesco
Chin, Mary Pik Wai
Dos Santos Augusto, Ricardo M
Ferrari, Alfredo
Garcia Ortega, Pablo
Kozlowska, Wioletta S
Magro, Giuseppe
Mairani, Andrea
Parodi, Katia
Sala, Paola R
Schoofs, Philippe
Tessonnier, Thomas
Vlachoudis, Vasilis
author_facet Battistoni, Giuseppe
Bauer, Julia
Böhlen, Till T
Cerutti, Francesco
Chin, Mary Pik Wai
Dos Santos Augusto, Ricardo M
Ferrari, Alfredo
Garcia Ortega, Pablo
Kozlowska, Wioletta S
Magro, Giuseppe
Mairani, Andrea
Parodi, Katia
Sala, Paola R
Schoofs, Philippe
Tessonnier, Thomas
Vlachoudis, Vasilis
author_sort Battistoni, Giuseppe
collection CERN
description Monte Carlo (MC) codes are increasingly spreading in the hadrontherapy community due to their detailed description of radiation transport and interaction with matter. The suitability of a MC code for application to hadrontherapy demands accurate and reliable physical models capable of handling all components of the expected radiation field. This becomes extremely important for correctly performing not only physical but also biologically-based dose calculations, especially in cases where ions heavier than protons are involved. In addition, accurate prediction of emerging secondary radiation is of utmost importance in innovative areas of research aiming at in-vivo treatment verification. This contribution will address the recent developments of the FLUKA MC code and its practical applications in this field. Refinements of the FLUKA nuclear models in the therapeutic energy interval lead to an improved description of the mixed radiation field as shown in the presented benchmarks against experimental data with both 4 He and 12 C ion beams. Accurate description of ionization energy losses and of particle scattering and interactions lead to the excellent agreement of calculated depth-dose profiles with those measured at leading European hadron therapy centers, both with proton and ion beams. In order to support the application of FLUKA in hospital based environments, Flair, the FLUKA graphical interface, has been enhanced with the capability of translating CT DICOM images into voxel-based computational phantoms in a fast and well-structured way. The interface is capable of importing also radiotherapy treatment data described in DICOM RT standard.In addition the interface is equipped with an intuitive PET scanner geometry generator and automatic recording of coincidence events. Clinically similar cases will be presented both in terms of absorbed dose and biological dose calculations describing the various available features.
id cern-2150047
institution Organización Europea para la Investigación Nuclear
language eng
publishDate 2016
record_format invenio
spelling cern-21500472022-08-10T12:39:14Zdoi:10.3389/fonc.2016.00116http://cds.cern.ch/record/2150047engBattistoni, GiuseppeBauer, JuliaBöhlen, Till TCerutti, FrancescoChin, Mary Pik WaiDos Santos Augusto, Ricardo MFerrari, AlfredoGarcia Ortega, PabloKozlowska, Wioletta SMagro, GiuseppeMairani, AndreaParodi, KatiaSala, Paola RSchoofs, PhilippeTessonnier, ThomasVlachoudis, VasilisThe FLUKA code: An accurate simulation tool for particle therapyHealth Physics and Radiation EffectsMonte Carlo (MC) codes are increasingly spreading in the hadrontherapy community due to their detailed description of radiation transport and interaction with matter. The suitability of a MC code for application to hadrontherapy demands accurate and reliable physical models capable of handling all components of the expected radiation field. This becomes extremely important for correctly performing not only physical but also biologically-based dose calculations, especially in cases where ions heavier than protons are involved. In addition, accurate prediction of emerging secondary radiation is of utmost importance in innovative areas of research aiming at in-vivo treatment verification. This contribution will address the recent developments of the FLUKA MC code and its practical applications in this field. Refinements of the FLUKA nuclear models in the therapeutic energy interval lead to an improved description of the mixed radiation field as shown in the presented benchmarks against experimental data with both 4 He and 12 C ion beams. Accurate description of ionization energy losses and of particle scattering and interactions lead to the excellent agreement of calculated depth-dose profiles with those measured at leading European hadron therapy centers, both with proton and ion beams. In order to support the application of FLUKA in hospital based environments, Flair, the FLUKA graphical interface, has been enhanced with the capability of translating CT DICOM images into voxel-based computational phantoms in a fast and well-structured way. The interface is capable of importing also radiotherapy treatment data described in DICOM RT standard.In addition the interface is equipped with an intuitive PET scanner geometry generator and automatic recording of coincidence events. Clinically similar cases will be presented both in terms of absorbed dose and biological dose calculations describing the various available features.oai:cds.cern.ch:21500472016
spellingShingle Health Physics and Radiation Effects
Battistoni, Giuseppe
Bauer, Julia
Böhlen, Till T
Cerutti, Francesco
Chin, Mary Pik Wai
Dos Santos Augusto, Ricardo M
Ferrari, Alfredo
Garcia Ortega, Pablo
Kozlowska, Wioletta S
Magro, Giuseppe
Mairani, Andrea
Parodi, Katia
Sala, Paola R
Schoofs, Philippe
Tessonnier, Thomas
Vlachoudis, Vasilis
The FLUKA code: An accurate simulation tool for particle therapy
title The FLUKA code: An accurate simulation tool for particle therapy
title_full The FLUKA code: An accurate simulation tool for particle therapy
title_fullStr The FLUKA code: An accurate simulation tool for particle therapy
title_full_unstemmed The FLUKA code: An accurate simulation tool for particle therapy
title_short The FLUKA code: An accurate simulation tool for particle therapy
title_sort fluka code: an accurate simulation tool for particle therapy
topic Health Physics and Radiation Effects
url https://dx.doi.org/10.3389/fonc.2016.00116
http://cds.cern.ch/record/2150047
work_keys_str_mv AT battistonigiuseppe theflukacodeanaccuratesimulationtoolforparticletherapy
AT bauerjulia theflukacodeanaccuratesimulationtoolforparticletherapy
AT bohlentillt theflukacodeanaccuratesimulationtoolforparticletherapy
AT ceruttifrancesco theflukacodeanaccuratesimulationtoolforparticletherapy
AT chinmarypikwai theflukacodeanaccuratesimulationtoolforparticletherapy
AT dossantosaugustoricardom theflukacodeanaccuratesimulationtoolforparticletherapy
AT ferrarialfredo theflukacodeanaccuratesimulationtoolforparticletherapy
AT garciaortegapablo theflukacodeanaccuratesimulationtoolforparticletherapy
AT kozlowskawiolettas theflukacodeanaccuratesimulationtoolforparticletherapy
AT magrogiuseppe theflukacodeanaccuratesimulationtoolforparticletherapy
AT mairaniandrea theflukacodeanaccuratesimulationtoolforparticletherapy
AT parodikatia theflukacodeanaccuratesimulationtoolforparticletherapy
AT salapaolar theflukacodeanaccuratesimulationtoolforparticletherapy
AT schoofsphilippe theflukacodeanaccuratesimulationtoolforparticletherapy
AT tessonnierthomas theflukacodeanaccuratesimulationtoolforparticletherapy
AT vlachoudisvasilis theflukacodeanaccuratesimulationtoolforparticletherapy
AT battistonigiuseppe flukacodeanaccuratesimulationtoolforparticletherapy
AT bauerjulia flukacodeanaccuratesimulationtoolforparticletherapy
AT bohlentillt flukacodeanaccuratesimulationtoolforparticletherapy
AT ceruttifrancesco flukacodeanaccuratesimulationtoolforparticletherapy
AT chinmarypikwai flukacodeanaccuratesimulationtoolforparticletherapy
AT dossantosaugustoricardom flukacodeanaccuratesimulationtoolforparticletherapy
AT ferrarialfredo flukacodeanaccuratesimulationtoolforparticletherapy
AT garciaortegapablo flukacodeanaccuratesimulationtoolforparticletherapy
AT kozlowskawiolettas flukacodeanaccuratesimulationtoolforparticletherapy
AT magrogiuseppe flukacodeanaccuratesimulationtoolforparticletherapy
AT mairaniandrea flukacodeanaccuratesimulationtoolforparticletherapy
AT parodikatia flukacodeanaccuratesimulationtoolforparticletherapy
AT salapaolar flukacodeanaccuratesimulationtoolforparticletherapy
AT schoofsphilippe flukacodeanaccuratesimulationtoolforparticletherapy
AT tessonnierthomas flukacodeanaccuratesimulationtoolforparticletherapy
AT vlachoudisvasilis flukacodeanaccuratesimulationtoolforparticletherapy